Auteurs : BEN ABDALLAH CHABCHOUB R,TURKI H,MAHFOUDH A,

Titre : [Systemic lupus erythematosus in a boy with chronic granulomatous disease: Casereport and review of the literature].

Référence : Arch Pediatr. 2014 Dec;21(12):1364-6. doi: 10.1016/j.arcped.2014.09.011. Epub2014 Oct 27.

Résumé :

The association of chronic granulomatosis disease (CGD) with autoimmune diseasessuch as lupus has been described but remains rare. K... is a boy born of aconsanguineous marriage. In the family history, two brothers had died at a youngage. He had been followed up since the age of 6months for CGD. At 11years of age,he developed malar rash, cheilitis, oral ulceration, and photosensitivity.Systemic lupus erythematosus (SLE) was confirmed by the presence of high levelsof antinuclear antibodies. This ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : AJMI H,LAHMAR I,ZOUARI N,KADRI K,HASSAYOUN S,BELKADHI M,CHEMLI J,ABROUG S,TLILI K,HARBI A,

Titre : [A rare cause of recurrent meningitis in children: Cochleovestibular dysplasia.]LID - S0929-693X(14)00370-4 [pii]LID - 10.1016/j.arcped.2014.08.025 [doi]

Référence : Arch Pediatr. 2014 Oct 1. pii: S0929-693X(14)00370-4. doi:10.1016/j.arcped.2014.08.025.

Résumé :

Recurrent bacterial meningitis is an uncommon disease of childhood. It occursmost often in children who have an underlying predisposing disorder that canresult from anatomic fistula or immunodeficiency. Cochleovestibular dysplasia isa rare malformation of the inner ear that is often associated withtranslabyrinthine cerebrospinal fistula and then can cause recurrent bacterialmeningitis. We report an unusual case of recurrent meningitis revealingcochleovestibular dysplasia in a 9-year-old child. T ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BORGI A,MENIF K,BELHADJ S,GHALI N,SALMEN L,HAMDI A,KHALDI A,BOUAFFSOUN A,KECHAOU S,KECHRID A,BOUZIRI A,BENJABALLAH N,

Titre : Predictors of Mortality in Mechanically Ventilated Critical Pertussis in a lowIncome Country.

Référence : Mediterr J Hematol Infect Dis. 2014 Sep 1;6(1):e2014059. doi:10.4084/MJHID.2014.059. eCollection 2014.

Résumé :

BACKGROUND: Critical pertussis is characterized by severe respiratory failure,important leukocytosis, pulmonary hypertension, septic shock and encephalopathy.AIM: To describe the clinical course of critical pertussis, and identifypredictors of death at the time of presentation for medical care. METHODOLOGY:Retrospective study conducted in children's hospital Tunisian PICU between 01January and 31 October 2013. Patients with critical pertussis confirmed by RT-PCRand requiring mechanical ventilati ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TABBABI A,RHIM A,GHRAB J,MARTIN O,AOUN K,BOURATBINE A,READY PD,

Titre : Phlebotomus (Paraphlebotomus) riouxi: a synonym of Phlebotomus chabaudi withoutany proven vectorial role in Tunisia and Algeria.

Référence : Med Vet Entomol. 2014 Aug;28 Suppl 1:51-9. doi: 10.1111/mve.12067.

Résumé :

Phlebotomus (Paraphlebotomus) riouxi Depaquit, Leger & Killick-Kendrick (Diptera:Psychodidae) was described as a typological species based on a few morphologicalcharacters distinguishing it from Phlebotomus (Paraphlebotomus) chabaudi Croset,Abonnenc & Rioux. The naming of P. riouxi coincided with its incrimination as arural vector of Leishmania tropica Wright (junior synonym: Leishmania killickiRioux, Lanotte & Pratlong) in Tataouine governorate, an arid region of southernTunisia. The current re ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : GARGOURI L,BOUDABOUS M,SAFI F,MAALEJ B,MNIF H,CHTOUROU L,MEJDOUB I,MNIF L,AMOURI A,BOUDAWARA T,TAHRI N,MAHFOUDH A,

Titre : [Crohn's disease or intestinal tuberculosis: A diagnostic challenge.]LID - S0929-693X(14)00333-9 [pii]LID - 10.1016/j.arcped.2014.07.008 [doi]

Référence : Arch Pediatr. 2014 Aug 25. pii: S0929-693X(14)00333-9. doi:10.1016/j.arcped.2014.07.008.

Résumé :

Distinguishing intestinal tuberculosis from Crohn disease is difficult and canresult in misdiagnosis, especially when active pulmonary infection is absent. A13-year-old girl was admitted to our hospital with a 2-month history of waterydiarrhea, abdominal pain, and 12-kg weight loss. Based on clinical, radiological,endoscopic, and histological findings, she was initially misdiagnosed as havingCrohn disease and treated with glucocorticosteroids, with a poor response after 4weeks. Intestinal tuberc ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : AMEUR SB,ALOULOU H,NASRALLAH F,KAMOUN T,KAABACHI N,HACHICHA M,

Titre : Hemolytic Anemia and Metabolic Acidosis: Think about Glutathione SynthetaseDeficiency.

Référence : Fetal Pediatr Pathol. 2014 Aug 28.

Résumé :

Glutathione synthetase deficiency (GSSD) is a rare disorder of glutathionemetabolism with varying clinical severity. Patients may present with hemolyticanemia alone or together with acidosis and central nervous system impairment.Diagnosis is made by clinical presentation and detection of elevatedconcentrations of 5-oxoproline in urine and low glutathione synthetase activityin erythrocytes or cultured skin fibroblasts. The prognosis seems to depend onearly diagnosis and treatment. We report a 4 m ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUYAHIA O,JLIDI S,SAMMOUD A,

Titre : [Primitive lung abscess: An unusual situation in children.]LID - S0761-8417(14)00081-9 [pii]LID - 10.1016/j.pneumo.2014.04.004 [doi]

Référence : Rev Pneumol Clin. 2014 Aug 14. pii: S0761-8417(14)00081-9. doi:10.1016/j.pneumo.2014.04.004.

Résumé :

INTRODUCTION: Lung abscess is a localized area of non tuberculosis suppurativenecrosis of the parenchyma lung, resulting in formation of a cavity containingpurulent material. This pathology is uncommon in childhood. CASE REPORT: A3-year-6 month-old boy was admitted with prolonged fever and dyspnea. Chest X-rayshowed a non systemized, well limited, thick walled, hydric, and excavatedopacity containing an air-fluid level. Chest ultrasound examination showed acollection of 6. 8cm of diameter in the ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : SFAIHI L,KASSAR O,MEDHAFFAR M,KAMOUN T,HADIJI S,ALOULOU H,BELLAJ H,AJMI N,CHABCHOUB I,ELLOUMI M,HACHICHA M,

Titre : Primary immune thrombocytopenia in childhood: a regional study in the south ofTunisia.

Référence : Tunis Med. 2014 Mar;92(3):219-23.

Résumé :

Background: the primary immune thrombocytopenia (ITP) in children has a favorableevolution in most of cases. aim: describe the epidemiological and therapeuticdata and the outcome of primary immune thrombocytopenia in our patients andpropose a treatment plan to standardize the management of this disease in ourregion. methods: We conducted a retrospective study of 140 cases of primaryimmune thrombocytopenia collected in department of pediatrics and hematology ofHedi Chaker hospital during a period ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : TINSA F,HAMOUDA S,BELLALAH M,BOUSNINA D,KARBOUL L,BOUSSETTA K,BOUSNINA S,

Titre : Unusual feature of pycnodysostosis: pectus carinatum.

Référence : Tunis Med. 2014 Feb;92(2):180-1.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : SFAIHI L,AISSA K,FOURATI H,KAMOUN F,MNIF Z,KAMOUN T,HACHICHA M,

Titre : Klippel Trenaunay syndrome in association with Sturge Weber syndrome about onecase.

Référence : Tunis Med. 2014 Feb;92(2):173-4.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SFAIHI L,KAMOUN F,KAMOUN T,ALOULOU H,MEZGHANI S,HAMMEMI A,HACHICHA M,

Titre : [Bacterial meningitis in children: epidemiological data and outcome].

Référence : Tunis Med. 2014 Feb;92(2):141-6.

Résumé :

BACKGROUND: The bacterial meningitis in children remains a worrisome affectionboth by its frequency and by its gravity. AIM: describe the epidemiological,clinical and evolutionary data of bacterial meningitis in children aged between 3months and 15 years. METHODS: we conducted a retrospective study of all cases ofbacterial meningitis collected in the department of pediatrics of Hedi Chakerhospital, during a period of 6 years (2006-2011). We analyzed the filesretrospectively and we studied the ep ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : MAALOUL I,ALOULOU H,FOURATI H,SFAIHI L,CHABCHOUB I,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Hereditary hemorrhagic telangiectasia: Report of a pediatric case].

Référence : Arch Pediatr. 2014 Jul;21(7):768-71. doi: 10.1016/j.arcped.2014.04.021. Epub 2014Jun 13.

Résumé :

Hereditary hemorrhagic telangiectasia, or Rendu-Osler-Weber syndrome, is anautosomal dominant multiorgan disorder. This multisystemic vascular dysplasia isdetermined by a mutation of one of two main genes, endoglin (ENG) or HHT1, orACVRL1 or HHT2. These mutations induce vascular disorders that cause recurrentepistaxis and eventually multiple telangiectasia and arteriovenous visceralmalformations. We report the case of a 7-year-old girl who developed severehypoxemia due to multiple pulmonary arte ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN ABDALLAH CHABCHOUB R,MAALEJ B,GARGOURI L,TURKI F,MAJDOUB I,KESKES H,BARBOUCHE R,BEN HALIMA N,MAHFOUDH A,

Titre : [Serratia marcescens osteomyelitis as the first manifestation of chronicgranulomatous disease].

Référence : Arch Pediatr. 2014 Jul;21(7):754-6. doi: 10.1016/j.arcped.2014.04.023. Epub 2014Jun 13.

Résumé :

Chronic granulomatous disease is a rare, primary immunodeficiency disordercharacterized by a defect in oxidative metabolism in phagocytes and recurrentbacterial and fungal infections. We report a case in a 2-month-old infantadmitted with metacarpic osteomyelitis due to Serratia marcescens. Chronicgranulomatous disease is rare but must be considered in cases of uncommon oratypical infection. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUYAHIA O,BEN MESSOUD S,FRIHA F,FITOURI Z,BEN BECHER S,SAMMOUD A,

Titre : Management and outcome of bronchiectasis in children.

Référence : Tunis Med. 2014 Jan;92(1):76.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN AMEUR S,ALOULOU H,SFAIHI L,YAICH S,MNIF Z,KAMOUN T,HACHICHA M,

Titre : Cerebral imaging in epileptic children : study of 140 cases.

Référence : Tunis Med. 2014 Jan;92(1):24-8.

Résumé :

Background: Epilepsy is a chronic disease, often with an onset during childhoodand characterized by spontaneous and recurrent seizures. It concerns 0.5-1% ofchildren under 16 years of age. Being much more sensitive than computedtomography, magnetic resonance imaging is the technique of choice to identify anunderlying cause. CT scan is used in emergency situations. aim : To describecerebral lesions in epilepetic children and to identify predicative factors ofabnormal neuroimaging. methods : Autho ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : AISSA K,KAMOUN F,SFAIHI L,SLIM GHEDIRA E,ALOULOU H,KAMOUN T,PISSARD S,HACHICHA M,

Titre : Hemolytic Anemia and Progressive Neurologic Impairment: Think AboutTriosephosphate Isomerase Deficiency.

Référence : Fetal Pediatr Pathol. 2014 May 19.

Résumé :

We have reported the first Tunisian case of triosephosphate isomerase (TPI)deficiency in a 2-year-old girl. She was the first child of a nonconsanguineouscouple. The disease included a neonatal onset of chronic hemolytic anemia,recurrent low-respiratory infections then progressive neurological involvement.The diagnosis was made after her death from the TPI values of her parents whoexhibited intermediate enzyme deficiency. Molecular study of TPI genes showedthat the father and the mother are hete ...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Nabeul Mohamed Tlatli

____________________________________________________________________________________


Auteurs : HAMMAMI S,BESBES H,HADDED S,LAJMI K,MERIEM CB,GHEDIRA L,GUEDICHE MN,

Titre : Mumps Infection Associated with Intravascular Hemolysis, Acute Renal Failure andPancreatitis.

Référence : Indian J Pediatr. 2014 Apr 15.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : SIALA N,AZZABI O,KEBAIER H,MRAD R,REBAH O,BARBOUCHE R,BEJAOUI M,HALIOUI S,MAHERZI A,

Titre : Omenn syndrome: two case reports.

Référence : Acta Dermatovenerol Croat. 2013 Dec;21(4):259-62.

Résumé :

Omenn syndrome is a variant of combined severe immunodeficiency due to mutationsin RAG genes. It is characterized by polymorph symptoms and lethal outcome. Wereport on two cases of Omenn syndrome. Infants were aged 50 and 46 days. Theclinical and biological signs were typical and complete in the first case. In thesecond case, only the cutaneous signs were present. Diagnosis was confirmed bygenetic study. The Rag1 T631 mutation was found in these two patients.Hematopoietic stem cell transplantati ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : KSIA A,YENGUI H,SAAD MB,SAHNOUN L,MAAZOUN K,RACHIDA L,KRICHENE I,MEKKI M,BELGUITH M,NOURI A,

Titre : Soave transanal one-stage endorectal pull-through in the treatment ofHirschsprung's disease of the child above two-year-old: A report of 20 cases.

Référence : Afr J Paediatr Surg. 2013 Oct-Dec;10(4):362-6. doi: 10.4103/0189-6725.125449.

Résumé :

Background: The definitive treatment of Hirschsprung's disease is the removal ofthe aganglionic bowel by a pull-through surgery. In most cases, this surgery isperformed in infancy or in the neonatal period as presentation in older childrenand adulthood is uncommon. Materials and Methods: It is a retrospective study of20 patients above two-year-old who underwent a transanal Soave one-stageendorectal pull-through procedure for Hirschsprung's disease between January 2002and December 2010. Results: ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : GARGOURI L,SAFI F,FOURATI H,KMIHA S,TURKI F,ZIDI F,MNIF Z,MAHFOUDH A,

Titre : Early-onset of multiple sclerosis in a 5-year-old girl.LID - S0929-693X(13)00648-9 [pii]LID - 10.1016/j.arcped.2013.12.010 [doi]

Référence : Arch Pediatr. 2014 Mar;21(3):291-5. doi: 10.1016/j.arcped.2013.12.010. Epub 2014Jan 24.

Résumé :

Childhood multiple sclerosis is a rare demyelinating autoimmune disease withparticular features. Onset of multiple sclerosis is extremely uncommon in earlychildhood, particularly before 6 years of age. We report the case of a 5-year-oldgirl admitted to the hospital for altered consciousness and rapid onset of righthemiparaplegia. Magnetic resonance imaging (MRI) of the brain showed multifocalwhite matter disease with T2 hyperintense oval lesions in subcortical,periventricular, and cerebellar hem ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : KAMOUN F,SFAIHI L,WALI M,KAMOUN T,HACHICHA M,

Titre : [An uncommon cause of hematemesis in children: Factor XI deficiency.]LID - S0929-693X(13)00642-8 [pii]LID - 10.1016/j.arcped.2013.12.004 [doi]

Référence : Arch Pediatr. 2014 Mar;21(3):296-8. doi: 10.1016/j.arcped.2013.12.004. Epub 2014Jan 21.

Résumé :

Congenital factor XI deficiency, also called hemophilia C, is a rare coagulationdisorder that is particularly common in Ashkenazi Jews. Individuals with factorXI deficiency may or may not have a mild bleeding tendency, which is typicallyprovoked by surgery or trauma. We report the case of a 5.5-year-old girl whopresented with abdominal pain, vomiting, and hematemesis. Biological tests showeda prolonged activated partial thromboplastin time (aPTT) of 113 s (control=29 s)caused by a constitutional ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SIALA N,BENZARTI A,BOUKTHIR S,BRINI I,SAMMOUD A,BOUSNINA S,BEN BECHER S,LAKHOUA R,FETHI B,HARBI A,GUEDDICHE N,SFAR T,HACHICHA M,BEN HARIZ M,MAHERZI A,

Titre : Pediatric Crohn's disease in Tunisia.

Référence : Tunis Med. 2013 Dec;91(12):715-23.

Résumé :

Crohn's disease occur mainly in adults. However, pediatric onset forms are notrare and have many characteristics. Aim: to study clinical, diagnostic,therapeutic and evolutive characteristics of crohn's disease in tunisianchildren. Methods: Retrospective multicenter study conducted in 10 pediatricdepartments on a period of 10 years (2000-2008) Results : 43 children wereincluded. The sex-ratio was 1.68. The mean age at the onset of the symptoms was11+/-2.3 years (5-16 years). The age of onset was ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : NAIJA O,BOUZARAA J,GOUCHA-LOUZIR R,GARGAH T,

Titre : Henoch Schonlein nephrites in children : clinical features and outcome : about 34cases.

Référence : Tunis Med. 2013 Dec;91(12):700-4.

Résumé :

Aim : To describe epidemiological, clinical, histological aspects, treatment andoutcome of Henoch-Schonlein nephrits in children. Methods : A retrospective studywas conducted on medical data of 34 patients with Henoch-Schonlein nephritis FromJanuary 1, 1996 to December 31, 2010 in the Pediatric Department of CharlesNicolle Hospital. Results : Nephritis occured in 68,7%. The average patient agewas 7 years 2 months and sex ratio was 0,6. Microscopic hematuria was noted in23,5%, moderate proteinuri ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : BEN AMEUR S,HENTATI Y,BEN DHAOUI M,WELI M,KAMOUN T,MNIF Z,MHIRI R,HACHICHA M,

Titre : [Neonatal renal candidiasis: A case report.]LID - S0929-693X(13)00646-5 [pii]LID - 10.1016/j.arcped.2013.12.008 [doi]

Référence : Arch Pediatr. 2014 Mar;21(3):287-90. doi: 10.1016/j.arcped.2013.12.008. Epub 2014Jan 20.

Résumé :

Neonatal renal candidiasis is an increasingly common condition affectingpredominantly premature infants receiving neonatal intensive care or term infantswith urogenital tract anomalies. Case report: a female infant was born bycesarian section at 30weeks' gestation to a mother whose pregnancy had beencomplicated by rupture of membranes for 5days. The infant was admitted at birth,maternofetal bacterial infection was suspected, and intravenous antibiotics wereprescribed. The patient developed sepsi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUAZIZ ABED A,MAALOUL I,MUSTAPHA R,CHIHA M,AISSA K,

Titre : Primary Hypertriglyceridemia type IV : severe incidentaloma of earlypresentation.

Référence : Tunis Med. 2013 Nov;91(11):683.

Résumé :

...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Nabeul Mohamed Tlatli

____________________________________________________________________________________


Auteurs : NAIJA O,SELMI I,RAJHI H,LAKHOUA MR,

Titre : Renal abscess in a healthy child.

Référence : Tunis Med. 2013 Nov;91(11):671.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Faculté de Médecine de Tunis

____________________________________________________________________________________


Auteurs : MRAD SM,BOUKTHIR S,BRINI I,HACHICHA S,SAMOUD A,

Titre : Endoscopic diagnosis in a Tunisian paediatric population with uppergastrointestinal bleeding (uGIB).

Référence : Tunis Med. 2013 Nov;91(11):655-60.

Résumé :

Background: Esophagogastroduodenoscopy (EGD) is currently considered the firstline diagnostic procedure chosen for Upper Gastrointestinal Bleeding (UGIB) since1970. However, studies are still limited in our country. aim: Finding out themost common causes of UGIB in children and whether the causes differed accordingto age in developing and developed countries. methods: A retrospective review ofthe medical records of children referred to the Paediatric GastroenterologyDepartment of The Tunis Hospi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : ABED AB,SAAD H,MUSTPHA R,CHIHA M,BEN GAMRA S,

Titre : Early hearning screening by otoacoustic emissions and auditory brain stemresponse in nabeul.

Référence : Tunis Med. 2013 Nov;91(11):643-7.

Résumé :

Background: Hearing loss is the most common congenital abnormality with areported prevalence of 1 to 3 per thousand live births. Early detection andintervention is critical to prevent the adverse consequences of a delayeddiagnosis on speech language and cognitive development. aim: study the frequencyof deafness in the newborns and the infants under 6 months followed in TlatliHospital in Nabeul and to search for correlations with risk factors identified bythe Joint Committee on Infant Screening. ...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Nabeul Mohamed Tlatli

____________________________________________________________________________________


Auteurs : MALOUCHE S,BOUSSETTA K,BEN HASSINE L,MALOUCHE K,SIALA M,NESSIB F,MONGALGI MA,BEN HASSEN A,REJEB S,BOUSSNINA S,

Titre : Skin sensitization to aeroallergens in the child: cross-sectional study of 200cases.

Référence : Tunis Med. 2013 Nov;91(11):627-32.

Résumé :

Background: The prevalence of the allergic diseases increased considerably duringthe last decades. The clinical expression of allergy depends on the interactionof genetic and environmental factors. aim: The aim of our study was to evaluatethe prevalence of sensitizing to aeroallergens in the child and to determine therisk factors of sensitizing. methods: We carried out a cross-sectional studyrelating to 200 pediatric patients of the Mahmoud El Matri hospital, aged from 3to14 years. We performed ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire de Pneumo-Phtisiologie Mahmoud Matri

____________________________________________________________________________________


Auteurs : BORGI A,BOUZIRI A,BOUJELBENE N,SGHAIROUN N,BELHADJ S,BENJEBALLAH N,

Titre : Perforated Meckel's Diverticulum in a Very Preterm Baby Revealed at Birth.

Référence : Fetal Pediatr Pathol. 2014 Apr;33(2):119-22. doi: 10.3109/15513815.2013.850133.Epub 2013 Dec 13.

Résumé :

Perforated Meckel's diverticulum (MD) in a preterm baby is very rare. We report acase of a very preterm baby, born at 29-week gestation, with a birth weight of1400 g, admitted in the third hour of life to our intensive care unit (ICU) forrespiratory distress syndrome with abdominal distention. An abdominal radiographshowed a pneumoperitoneum. Laparotomy revealed Meckel's perforation. The baby wasdischarged healthy at the age of 16 days. MD should be kept in mind as one causeof an acute abdomen i ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN ABDALLAH CHABCHOUB R,KMIHA S,TURKI F,TRABELSI L,MAALEJ B,BEN SALAH M,ABDELHEDI GARGOURI L,BOUKEDI A,BEN HALIMA N,MAHFOUDH A,

Titre : [Septic cavernous sinus thrombosis following ethmoiditis: A case report.]LID - S0929-693X(13)00566-6 [pii]LID - 10.1016/j.arcped.2013.10.012 [doi]

Référence : Arch Pediatr. 2014 Jan;21(1):66-9. doi: 10.1016/j.arcped.2013.10.012. Epub 2013Nov 26.

Résumé :

Acute ethmoiditis is a rare infection of ethmoidal cells. The pathognomonic signis an edema of the internal corner of the eye. Imaging may be necessary to verifythe absence of orbital or endocranial complications. Thrombophlebitis of thecavernous sinus is a serious complication of this infectious process. We reportthe case of an 11-year-old boy who presented with ethmoiditis complicated withthrombophlebitis of the cavernous sinus, with right hemiplegia and left Bellpalsy sequelae. Early diagnosi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : GARGOURI L,MNIF L,SAFI F,TURKI F,MAJDOUB I,MAALEJ B,BAHRI I,MNIF H,BOUDAWARA T,TAHRI N,MAHFOUDH A,

Titre : Type 2 autoimmune hepatitis overlapping with primary sclerosing cholangitis in a10-year-old boy.

Référence : Arch Pediatr. 2013 Dec;20(12):1325-8. doi: 10.1016/j.arcped.2013.09.020. Epub2013 Oct 29.

Résumé :

BACKGROUND: Overlap syndrome of autoimmune hepatitis (AIH) and primary sclerosingcholangitis (PSC) is considered when the patient presents with the diagnosticcriteria of both diseases at some stage of the medical history, eithersimultaneously or consecutively. AIM: To report on a new case of overlap syndromeand describe the clinical presentation, progression, radiological studies,histological characteristics, and therapeutic options of this rare association.CASE REPORT: A 10-year-old boy present ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN GHARBIA H,GARTNER A,TRAISSAC P,DELPEUCH F,MAIRE B,EL ATI J,

Titre : A frequency questionnaire to estimate free-living physical activity amongTunisian preadolescent and adolescent children.

Référence : Public Health Nutr. 2013 Oct 14:1-10.

Résumé :

OBJECTIVE: To develop a child- and adolescent-appropriate physical activityfrequency questionnaire (PAFQ) in Tunisia, North Africa. DESIGN: A PAFQ wasdeveloped from a physical activity (PA) inventory that comprised major activitycomponents (at home, preparing meals, school time, transport, non-sport leisure,sports, prayer and sleeping time). Then, type and duration of each activityundertaken during the past week were estimated. Total energy expenditure (TEE)estimated by the PAFQ was compared wit ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Institut National de Nutrition et de Technologie Alimentaire

____________________________________________________________________________________


Auteurs : HAMMAMI S,BESBES H,HADDED S,LAJMI K,GHEDIRA L,MERIEM CHB,GUEDICHE MN,

Titre : Hypoxemic Bronchiolitis Related to Major Histocompatibility Class II Deficiency.

Référence : Case Rep Med. 2013;2013:315073. doi: 10.1155/2013/315073. Epub 2013 Aug 24.

Résumé :

Major histocompatibility complex class II expression deficiency is an autosomalrecessive primary combined immunodeficiency. The prevalence of this deficiency isthe highest in Mediterranean areas, especially North Africa. Early diagnosis isessential due to high mortality in the first 2 years of life. Prognosis is verypoor when bone marrow transplantation cannot be performed. We report the case ofan infant with major histocompatibility complex class II expression deficiencyrevealed by hypoxemic br ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : GHRIBI A,KRICHENE I,FEKIH HASSEN A,MEKKI M,BELGHITH M,NOURI A,

Titre : Gastric perforation in the newborn.

Référence : Tunis Med. 2013 Jul;91(7):464-7.

Résumé :

Background: Gastric perforation in neonates is an uncommon condition. It could bespontaneous but a contributing cause should be sought. aim: To review ourexperience of treating 8 neonates with gastric perforation over the past 20years. methods: We reviewed the records of all newborns admitted to our hospitalbetween 1990 and 2010 with regard to gender, age at admission, contributingfactors, associated anomalies, site of perforation, type of operation, andoutcome. results: Of the eight neonates, f ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : HARIZ MB,LAADHAR L,KALLEL-SELLAMI M,SIALA N,BOURAOUI S,BOUZIRI S,BORGI A,KAROUIA F,MAHERZI A,MAKNI S,

Titre : Celiac disease in Tunisian children: A second screening study using a "newgeneration" rapid test.

Référence : Immunol Invest. 2013;42(4):356-68. doi: 10.3109/08820139.2013.770012.

Résumé :

This work aims to estimate celiac disease prevalence in school-children in theisland of Djerba and assess rapid method feasibility for screening. We screened2064 schoolchildren by a rapid method to detect IgA anti-tissue transglutaminaseand IgA deficiency. Children with positive results were tested for IgAanti-transglutaminase and anti-endomysium by conventional tests. In positivechildren, intestinal biopsy was performed. IgA deficiency suspected by rapidmethod was confirmed by nephelometry. In ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : SFAIHI L,MAALOUL I,HENTATI Y,KAMOUN F,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Dystonia, megalencephaly, and seizure: Think about type I glutaric aciduria].

Référence : Arch Pediatr. 2013 Aug;20(8):900-2. doi: 10.1016/j.arcped.2013.05.004. Epub 2013Jul 5.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SFAIHI L,MAALOUL I,HENTATI Y,KAMOUN F,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Dystonia, megalencephaly, and seizure].

Référence : Arch Pediatr. 2013 Aug;20(8):876, 900-2. doi: 10.1016/j.arcped.2013.05.007. Epub2013 Jul 5.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN ABDALLAH CHABCHOUB R,BOUKEDI A,BENSALAH M,MAALEJ B,GARGOUR L,TURK F,BEN HALIMA N,WOLF M,VEYRADIER A,MAHFOUDH A,

Titre : [Atypical hemolytic and uremic syndrome associated with von Willebrandfactor-cleaving protease (ADAMTS 13) deficiency in children].

Référence : Arch Pediatr. 2013 Aug;20(8):853-7. doi: 10.1016/j.arcped.2013.05.001. Epub 2013Jul 1.

Résumé :

Hemolytic and uremic syndrome (HUS) is a classical form of thromboticmicroangiopathies characterized by the association of hemolytic anemia withschizocytes, thrombocytopenia, and acute renal failure. Two forms of HUS havebeen described: the typical form that occurs after ingestion of a strain ofbacteria, usually Escherichia coli types, which expresses verotoxin (also calledshiga-like toxin), typically followed by bloody diarrhea, and atypical HUS, whichis rare during childhood and can also be re ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BORGI A,KHEMIRI M,VEYRADIER A,KAZDAGHLI K,BARSAOUI S,

Titre : Congenital Thrombotic Thrombocytopenic Purpura: Atypical Presentation and NewADAMTS 13 Mutation in a Tunisian Child.

Référence : Mediterr J Hematol Infect Dis. 2013 Jun 3;5(1):e2013041. doi:10.4084/MJHID.2013.041. Print 2013.

Résumé :

BACKGROUND: Congenital deficiency of ADAMTS13 is characterized by systemicplatelet clumping, hemolytic anemia and multiorgan failure. Although, more than100 mutations have been reported, atypical clinical presentation may be involvedin diagnostic difficulties. CASE REPORT: A 2 year old Tunisian child presentedwith chronic thrombopenic purpura which failed to respond to corticosteroids.Hemolytic anemia with schistocytes, occurred ten months later, with no previoushistory of diarrhea or any neurol ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MAALOUL I,FOURATI H,WALI M,CHABCHOUB I,KAMOUN T,MNIF Z,KAABACHI N,HACHICHA M,

Titre : [Megalencephaly with dystonia revealing Canavan disease].

Référence : Arch Pediatr. 2013 Jul;20(7):783-6. doi: 10.1016/j.arcped.2013.04.023. Epub 2013May 30.

Résumé :

Canavan disease, or N-acetyl aspartic aciduria, is an autosomal recessiveleukodystrophy characterized by spongy degeneration of the brain. The diseaseresults from the accumulation of N-acetyl aspartic acid in the brain, due toaspartoacylase deficiency. We report the case of a 6-month-old girl who presentedwith megalencephaly, peripheral hypertonia, and a developmental delay noticeableafter 4 months of age. Magnetic resonance imaging of the brain with spectroscopywas suggestive of Canavan disease ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUGUILA J,KHALEF I,BENALI M,SRIHA B,SOYAH N,BOUGHAMMOURA L,

Titre : [Tongue base schwannoma in a child].

Référence : Rev Stomatol Chir Maxillofac Chir Orale. 2013 Feb;114(1):46-8. doi:10.1016/j.stomax.2012.07.010. Epub 2012 Nov 22.

Résumé :

INTRODUCTION: A schwannoma is a benign slow growing tumor originating from theperipheral nerve sheath. Its tongue base location is extremely rare, especiallyin very young patients. CASE REPORT: A 15-year-old female patient was admitted inemergency for moderate hematemesis. The clinical examination revealed swelling ofthe tongue base, causing the bleeding. This lesion had appeared when she was3years of age and no treatment was done. A complete surgical excision wasperformed and the histopathologi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : HAMMAMI S,HARRATHI K,LAJMI K,HADDED S,BEN MERIEM C,GUEDICHE MN,

Titre : Congenital pulmonary alveolar proteinosis.

Référence : Case Rep Pediatr. 2013;2013:764216. doi: 10.1155/2013/764216. Epub 2013 Apr 27.

Résumé :

Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterized bypulmonary surfactant accumulation within the alveolar spaces. It occurs with areported prevalence of 0.1 per 100,000 individuals. Two clinically differentpediatric types have been defined as congenital PAP which is fatal and alate-onset PAP which is similar to the adult form and less severe. The clinicalcourse of PAP is variable, ranging from spontaneous remission to respiratoryfailure. Whole-lung lavage is the current stand ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : KAMOUN T,SFAIHI L,KAMOUN F,CHABCHOUB I,ALOULOU H,HACHICHA M,

Titre : Primary distal renal tubular acidosis in children in the South of Tunisia: Studyof 15 cases.

Référence : Tunis Med. 2013 Apr;91(4):258-62.

Résumé :

Background: primary distal renal tubular acidosis in children (RTA) ischaracterized by metabolic acidosis due to defect in urinary excretion ofhydrogen (H+) in the distal tubular. aim: To report the epidemiological,clinical, therapeutic and evolutionary of distal RTA in our patients. Patientsand methods: We conducted a retrospective study of all cases of distal RTAcollected in the department of pediatrics of Hedi Chaker University hospital inthe south of Tunisia, during a period of 23 years (198 ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUGUILA J,MABROUK S,TILOUCHE S,BAKIR D,TRABELSI A,HMILA A,BOUGHAMMOURA L,

Titre : Giant cell hepatitis with autoimmune hemolytic anemia in a nine month old infant.

Référence : World J Hepatol. 2013 Apr 27;5(4):226-9. doi: 10.4254/wjh.v5.i4.226.

Résumé :

Giant cell hepatitis (GCH) with autoimmune hemolytic anemia is a rare entity,limited to young children, with an unknown pathogenesis. We report the case of9-mo old who presented with fever, diarrhea and jaundice four days beforehospitalization. Physical examination found pallor, jaundice andhepatosplenomegaly. The laboratory workup showed serum total bilirubin at 101mumol/L, conjugated bilirubin at 84 mumol/L, hemolytic anemia, thrombocytopeniaand immunoglobulin G (IgG) and anti-C3d positive dir ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : SFAIHI L,KAMOUN F,HENTATI Y,TISS O,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Prolonged fever in a 2-year-old child.]LID - S0929-693X(13)00234-0 [pii]LID - 10.1016/j.arcped.2013.03.018 [doi]

Référence : Arch Pediatr. 2013 Jun;20(6):665-6, 685-7. doi: 10.1016/j.arcped.2013.03.018.Epub 2013 Apr 22.

Résumé :

null ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SFAIHI L,KAMOUN F,HENTATI Y,TISS O,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Disseminated hydatidosis treated with albendazole.]LID - S0929-693X(13)00232-7 [pii]LID - 10.1016/j.arcped.2013.03.016 [doi]

Référence : Arch Pediatr. 2013 Apr 22. pii: S0929-693X(13)00232-7. doi:10.1016/j.arcped.2013.03.016.

Résumé :

null ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SFAIHI L,KAMOUN F,HENTATI Y,TISS O,MAALOUL I,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Posterior reversible encephalopathy syndrome induced by acute postinfectiousglomerulonephritis.]LID - S0929-693X(13)00230-3 [pii]LID - 10.1016/j.arcped.2013.03.014 [doi]

Référence : Arch Pediatr. 2013 Jun;20(6):633-6. doi: 10.1016/j.arcped.2013.03.014. Epub 2013Apr 22.

Résumé :

INTRODUCTION: Posterior reversible encephalopathy syndrome (PRES) is a clinicaland radiological entity characterized by neurologic symptoms in association withusually reversible bilateral posterior hemispheric edema on neuroimaging. It hasbeen described in adults more than in children. Many pathological conditions andtreatments have been associated with this syndrome. CASE REPORT: We report thecase of an 11-year-old boy who presented with acute postinfectiousglomerulonephritis, renal failure, an ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN ABDALLAH CHABCHOUB R,SAFI F,TRABELSI L,MAALEJ B,GARGOURI L,TURKI F,AMOURI M,BEN HALIMA N,TURKI H,MAHFOUD A,

Titre : [Hematidrosis in a child.]LID - S0929-693X(13)00187-5 [pii]LID - 10.1016/j.arcped.2013.02.068 [doi]

Référence : Arch Pediatr. 2013 May;20(5):563-4. doi: 10.1016/j.arcped.2013.02.068. Epub 2013Apr 3.

Résumé :

null ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUGUILA J,KHALEF I,CHARFEDDINE B,BEN REJEB M,CHATTI K,LIMAM K,ESSABBEH H,ESSOUSSI AS,BOUGHAMMOURA L,

Titre : [Comparative study of C-reactive protein and procalcitonin in the severitydiagnosis of pyelonephritis in children.]LID - S0369-8114(13)00042-4 [pii]LID - 10.1016/j.patbio.2013.01.010 [doi]

Référence : Pathol Biol (Paris). 2013 Jun;61(3):93-8. doi: 10.1016/j.patbio.2013.01.010. Epub2013 Mar 6.

Résumé :

OBJECTIVE: The aim of this study is to compare two biologic parameters;C-reactive protein (CRP) and procalcitonin (PCT) in the detection of acute renallesions assessed by DMSA scintigraphy in the urinary tract infection in child.DESIGN: In a prospective study, serum PCT, CRP and leukocyte counts were measuredfor children admitted, between January and December 2010, with a first episode offebrile urinary tract infection. RESULTS: Seventy-five children were enrolled inthe study. Thirty-three patie ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : BOUGUILA J,LAHMER I,ABDELKEFI M,AFFISSATH A,TRIMECHE M,BOUGHAMMOURA L,

Titre : Cervical unicentric Castleman's disease in children.LID - S1879-7296(13)00010-0 [pii]LID - 10.1016/j.anorl.2012.09.008 [doi]

Référence : Eur Ann Otorhinolaryngol Head Neck Dis. 2013 Mar 5. pii: S1879-7296(13)00010-0.doi: 10.1016/j.anorl.2012.09.008.

Résumé :

INTRODUCTION: Unicentric Castleman's disease (CD) is a rare benignlymphoproliferative disorder. A cervical location has rarely been reported in thepediatric literature. CASE REPORT: A 13-year-old boy presented with a mass in theright neck region of 3months' evolution. Clinical examination revealed a smoothmobile 5cm node deep in the sternocleidomastoid muscle. The diagnosis of hyalinevascular type CD was confirmed by complete surgical excision and histopathologicexamination. Postoperative course ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : LAMIA S,ALOULOU H,KAMOUN T,CHABCHOUB I,BEN MOUSTAPHA I,BARBOUCH R,MONGIA H,

Titre : Primary immunodeficiency disorders in 51 cases.

Référence : Tunis Med. 2013 Jan;91(1):38-43.

Résumé :

Background: Primary immunodeficiency disorders (PID) are a heterogeneous group ofdiseases, characterized by an increased susceptibility to infections. Aim: Todetermine the frequency of PID in south of Tunisia to collect information onclinical experience with these disorders. Methods: Over a period of 16 years(1995 - 2010), primary immunodeficiency was confirmed in 51 patients (31 boys and20 girls). The immunological investigation included a study of specific and/ornon specific humoral and cellul ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : TURKIA HB,GONZALEZ DE,BARTON NW,ZIMRAN A,KABRA M,LUKINA EA,GIRALDO P,KISINOVSKY I,BAVDEKAR A,DRIDI MF,GUPTA N,KISHNANI PS,SURESHKUMAR EK,WANG N,CROMBEZ E,BHIRANGI K,MEHTA A,

Titre : Velaglucerase alfa enzyme replacement therapy compared with imiglucerase inpatients with Gaucher disease.

Référence : Am J Hematol. 2013 Mar;88(3):179-84. doi: 10.1002/ajh.23382. Epub 2013 Feb 9.

Résumé :

Enzyme replacement therapy for Gaucher disease (GD) has been available since1991. This study compared the efficacy and safety of velaglucerase alfa withimiglucerase, the previous standard of care. A 9-month, global, randomized,double-blind, non-inferiority study compared velaglucerase alfa with imiglucerase(60 U/kg every other week) in treatment-naive patients aged 3-73 years withanemia and either thrombocytopenia or organomegaly. The primary endpoint was thedifference between groups in mean cha ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BEJAOUI M,GUIRAT N,

Titre : Beta thalassemia major in a developing country: epidemiological, clinical andevolutionary aspects.

Référence : Mediterr J Hematol Infect Dis. 2013;5(1):e2013002. doi: 10.4084/MJHID.2013.002.Epub 2013 Jan 2.

Résumé :

Beta-thalassemia major (TM) remains to be one of the major health problemsparticularly in developing countries. Tunisia is a part of the Mediterraneancountries mostly affected by this disease which is highly concentrated in smalltowns in families with low-income earners. The main objectives of this study areto provide a description of the demographic, clinical features andtransfusion-related complications in patients with TM living in Tunisia. Astandardized questionnaire was sent to clinicians t ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : SFAIHI L,ELLOUMI S,FOURATI H,KAMOUN T,MNIF Z,HACHICHA M,

Titre : Arterial ischemic stroke in children: 22 cases from southern Tunisia.

Référence : Fetal Pediatr Pathol. 2013 Jul;32(4):271-5. doi: 10.3109/15513815.2012.754523.Epub 2013 Jan 10.

Résumé :

The aim of this study is to review the cases of arterial ischemic stroke (AIS) inchildren in our department to evaluate the clinical and neuroimaging features,the etiologies and the treatment. This study retrospectively reviewed the recordsof all children aged between 1 month and 16 years who were admitted from 2000 to2010 for AIS in the pediatrics department of Hedi Chaker University hospital inSfax, Tunisia. Twenty-two children were enrolled. The average age at stroke was 3years and 2 months. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : MAZIGH MRAD S,ABIDI K,BRINI I,BOUKTHIR S,SAMMOUD A,

Titre : Nodular gastritis: An endoscopic indicator of Helicobacter pylori infection inchildren.

Référence : Tunis Med. 2012 Nov;90(11):789-92.

Résumé :

Background: Helicobacter pylori (Hp) infection is a common and universallydistributed bacterial infection. It is predominantly acquired in childhood. Aim:To assess the relationship between endoscopic nodular gastritis and Hp infection.Methods: A retrospective study was conducted in children who underwent uppergastrointestinal endoscopy for chronic abdominal pain. All children who had fivegastric biopsies for histologic analysis, urease test and Hp culture wereincluded in the study. The Sensitivi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUGUILA J,KHALEF I,BENALI M,SRIHA B,SOYAH N,BOUGHAMMOURA L,

Titre : [Tongue base schwannoma in a child.]LID - S0035-1768(12)00172-6 [pii]LID - 10.1016/j.stomax.2012.07.010 [doi]

Référence : Rev Stomatol Chir Maxillofac. 2012 Nov 22. pii: S0035-1768(12)00172-6. doi:10.1016/j.stomax.2012.07.010.

Résumé :

INTRODUCTION: A schwannoma is a benign slow growing tumor originating from theperipheral nerve sheath. Its tongue base location is extremely rare, especiallyin very young patients. CASE REPORT: A 15-year-old female patient was admitted inemergency for moderate hematemesis. The clinical examination revealed swelling ofthe tongue base, causing the bleeding. This lesion had appeared when she was3years of age and no treatment was done. A complete surgical excision wasperformed and the histopathologi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : EL ATI J,TRAISSAC P,DELPEUCH F,AOUNALLAH-SKHIRI H,BEJI C,EYMARD-DUVERNAY S,BOUGATEF S,KOLSTEREN P,MAIRE B,BEN ROMDHANE H,

Titre : Gender obesity inequities are huge but differ greatly according to environmentand socio-economics in a north african setting: a national cross-sectional studyin Tunisia.

Référence : PLoS One. 2012;7(10):e48153. doi: 10.1371/journal.pone.0048153. Epub 2012 Oct 31.

Résumé :

INTRODUCTION: Southern Mediterranean countries have experienced a marked increasein the prevalence of obesity whose consequences for gender related healthinequities have been little studied. We assessed gender obesity inequalities andtheir environmental and socio-economic modifiers among Tunisian adults. METHODS:Cross-sectional survey in 2005; national, 3 level random cluster sample of 35-70years Tunisians (women: n = 2964, men: n = 2379). Overall adiposity was assessedby BMI = weight(kg)/height ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Institut National de Nutrition et de Technologie Alimentaire

____________________________________________________________________________________


Auteurs : SFAIHI L,FOURATI H,KAMOUN F,HAKIM A,BEN MAHFOUDH F,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Edema of the lower limb.]LID - S0929-693X(12)00364-8 [pii]LID - 10.1016/j.arcped.2012.08.010 [doi]

Référence : Arch Pediatr. 2012 Nov;19(11):1217-8. doi: 10.1016/j.arcped.2012.08.010. Epub2012 Oct 16.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SFAIHI L,FOURATI H,KAMOUN F,HAKIM A,BEN MAHFOUDH F,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Sickle cell disease revealed by venous thrombosis.]LID - S0929-693X(12)00382-X [pii]LID - 10.1016/j.arcped.2012.08.027 [doi]

Référence : Arch Pediatr. 2012 Nov;19(11):1243-6. doi: 10.1016/j.arcped.2012.08.027. Epub2012 Oct 6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : SFAIHI L,MAALOUL I,FOURATI H,STASIA MJ,MNIF Z,HACHICHA M,

Titre : Resistant Invasive Aspergillosis in an Autosomal Recessive Chronic GranulomatousDisease.

Référence : Fetal Pediatr Pathol. 2013 Jul;32(4):241-5. doi: 10.3109/15513815.2012.721479.Epub 2012 Sep 24.

Résumé :

Chronic granulomatous disease (CGD) is an inherited immunodeficiencycharacterized by severe bacterial and fungal infections. Invasive aspergillosisand other rare mold diseases are the leading causes of mortality. We report onecase of CGD revealed by retropharyngeal abscess. On evolution, the patientdeveloped an invasive aspergillosis resistant to treatment. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : HAMZAOUI M,GASMI M,BEN AOUN J,FITOURI F,SGHAIROUN N,SAHLI S,

Titre : Urinary bladder gossypiboma in a child.

Référence : Tunis Med. 2012 Aug-Sep;90(8-9):665-6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : GARGAH T,CHERIF M,GOUCHA-LOUZIR R,LAKHOUA MR,

Titre : Severe pneumococcal hemolytic uremic syndrome in an 8-month-old girl.

Référence : Saudi J Kidney Dis Transpl. 2012 Sep;23(5):1024-7. doi: 10.4103/1319-2442.100885.

Résumé :

The hemolytic uremic syndrome (HUS), characterized by microangiopathic hemolyticanemia, thrombocytopenia and acute renal failure, represents one of the majorcauses of acute renal failure in infancy and childhood. The typical formoccurring after an episode of diarrhea caused by Escherichia coli is the mostfrequent in children. Other microorganisms also may be responsible for HUS, suchas Streptococcus pneumoniae, which causes more severe forms of the disease. Wereport an 8-month-old girl who prese ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : GHEDIRA BESBES L,HADDAD S,ABID A,BEN MERIEM CH,GUEDDICHE MN,

Titre : Pyogenic Sacroiliitis in Children: Two Case Reports.

Référence : Case Report Med. 2012;2012:415323. Epub 2012 Jul 5.

Résumé :

Pyogenic sacroiliitis is rare and accounts for approximately 1-2% ofosteoarticular infections in children. Considerable delay between presentationand diagnosis is recognized. Two cases of pyogenic sacroiliitis are described.The first case is a 28-month-old girl presented with acute onset of fever, painin the left hip, and limpness. Computed tomography (CT), bone scans, and magneticresonance imaging (MRI) of the pelvis showed characteristic findings ofinfectious sacroiliitis, and blood cultures w ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : ICHRAF K,NEZIHA GK,

Titre : Reply to Dr. Suresh Kumar.

Référence : Brain Dev. 2012 Jun 27.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Institut National de Neurologie Mongi Ben Hmida

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Auteurs : BOUAZIZ ABED A,BEN GAMRA S,MUSTAPHA R,CHIHA M,MAHERZI A,BOUSNINA S,

Titre : Cyclic vomiting syndrome in children.

Référence : Tunis Med. 2012 Jun;90(6):501-2.

Résumé :

...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Nabeul Mohamed Tlatli

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Auteurs : KHEMIRI M,EL FEKIH N,BORGI A,KHARFI M,BOUBAKER S,BARSAOUI S,

Titre : Pseudotumoral Cutaneous Aspergillosis in Chronic Granulomatous Disease, Report ofa Pediatric Case.AB - ABSTRACT:: Invasive aspergillosis is a life-threatening condition in patientswith chronic granulomatous disease (CGD). Skin invasion by Aspergillus occ

Référence : Am J Dermatopathol. 2012 Oct;34(7):749-52.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

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Auteurs : HAMZAOUI M,BEN AOUN J,JEMAI R,BEN SLAMA A,SGHAIROUN N,GASMI M,

Titre : Masse cervicale revelant une duplication kystique de l'oesophage.

Référence : Tunis Med. 2012 May;90(5):415-6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

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Auteurs : SFAIHI L,MAALOUL I,KMIHA S,ALOULOU H,CHABCHOUB I,KAMOUN T,HACHICHA M,

Titre : Febrile seizures: an epidemiological and outcome study of 482 cases.

Référence : Childs Nerv Syst. 2012 Oct;28(10):1779-84. Epub 2012 May 9.

Résumé :

INTRODUCTION: Febrile seizures (FSs) are the most common type of seizures seen inchildren. After the first FS, 3 to 12 % of children develop epilepsy, and 30 % ofthese patients present with recurrent FS. The purpose of this study was todescribe the epidemiological aspects of FS in order to better define thelong-term outcomes in children with first FS and to identify the risk factorsassociated with the recurrence of FS as well as the development of epilepsy.METHODS: A retrospective study of 482 c ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

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Auteurs : BOUZIRI A,DOUIRA W,KHALDI A,MRAD S,BOUYAHIA O,SMAOUI H,SAMMOUD A,MENIF K,JABALLAH NB,

Titre : Neurological Variant of Lemierre's Syndrome with Purulent Meningitis: A CaseReport and Literature Review.

Référence : Fetal Pediatr Pathol. 2013 Feb;31(1):1-6. doi: 10.3109/15513815.2011.618868. Epub2012 Apr 17.

Résumé :

We report an unusual variant of Lemierre's Syndrome (LS) in a 10-year-old-girladmitted to the intensive care unit for septic shock with meningitis. The primaryinfection was otitis media. A gram negative bacillus was identified in the directexam of the purulent ear discharge and the cerebrospinal fluid but cultures werenegative. Computerized tomography of the neck revealed a thrombus in the internaljugular vein. Septic shock improved rapidly under supportive treatment. Thepatient recovered withou ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

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Auteurs : SFAIHI L,ALOULOU H,BEN AMOR S,KAMOUN T,HACHICHA M,

Titre : Nephropathic Infantile Form of Cystinosis About One Case.

Référence : Fetal Pediatr Pathol. 2013 Feb;31(1):66-70. doi: 10.3109/15513815.2012.671445.Epub 2012 Apr 12.

Résumé :

Cystinosis is the major cause of inherited Fanconi syndrome, and should besuspected in young children with a failure to thrive and with signs of renalproximal tubular damage. This is a study of a case report of cystinosis revealedby a growth failure and chronic dehydration. A 9-month-old boy was referred toour department for evaluation of polyuria and polydipsia. Clinical examinationshowed dehydration and enlarged wrists and rachitic rosaries. The presence ofmetabolic acidosis, hypokalemia, hypo ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : GARGAH T,ABIDI K,NOURCHENE K,ZARROUK C,R LAKHOUA M,

Titre : Thromboembolic complications of childhood nephrotic syndrome.

Référence : Tunis Med. 2012 Feb;90(2):161-5.

Résumé :

Background: Vascular thrombosis in the childhood nephrotic syndrome is a rareevent. It poses major diagnostic and therapeutic problems. The prognosis dependson early diagnosis and on precocious anticoagulation. The risk of extension ofthrombosis and pulmonary embolism is real. Aims: To consider the major thromboticevents associated with childhood nephrotic syndrome and to establish anappropriate preventive approach based on objective clinical and laboratoryparameters. Methods: This is a retrospe ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

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Auteurs : GARGAH T,KHELIL N,YOUSSEF G,KAROUI W,LAKHOUA MR,ABDELMOULA J,

Titre : Primary hyperoxaluria type 1 in Tunisian children.

Référence : Saudi J Kidney Dis Transpl. 2012 Mar;23(2):385-90.

Résumé :

To determine the clinical, biological, and radiological futures of primaryhyper-oxaluria type 1 in Tunisian children, we retrospectively studied 44children with primary hyper-oxaluria type 1 who were treated in our center from1995 to 2009. The diagnosis was established by quantitative urinary oxalateexcretion. In patients with renal impairment, the diagnosis was made by infraredspectroscopy of stones or kidney biopsies. The male-to-female ratio was 1:2. Themedian age at diagnosis was 5.75 years. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

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Auteurs : WANNES S,SOUA H,GHANMI S,BRAHAM H,HASSINE M,HAMZA HA,BEN HAMOUDA H,SFAR MT,

Titre : [Neonatal renal vein thrombosis in a heterozygous carrier of both factor V Leidenand the MTHFR gene mutation.]

Référence : Arch Pediatr. 2012 Apr;19(4):419-21. Epub 2012 Feb 21.

Résumé :

Renal vein thrombosis (RVT) is a rare but potentially serious neonatal disease.Its epidemiology and its clinical and biological expression are currently wellknown, but its etiological exploration, like that of venous thromboembolism, isincreasingly complex. Perinatal risk factors such as prematurity, dehydration,and birth asphyxia have lost their direct accountability at the expense of theirinteraction with constitutional disorders of hemostasis. We report a case of RVTin a newborn who was a het ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Tahar Sfar

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Auteurs : MELLOULI F,KSOURI H,LAKHAL A,TORJMEN L,LADEB S,BEN OTHMAN T,HMIDA S,BEJAOUI M,

Titre : Autoimmune Polyglandular Syndrome Type II After Bone Marrow Transplant: RealTransfer or Acceleration of a Programmed Disease?

Référence : Exp Clin Transplant. 2012 Feb;10(1):76-80.

Résumé :

We report a case of autoimmune polyglandular syndrome type II that developed inan 11-year-old boy with homozygous sickle cell disease after allogeneic bonemarrow transplant; the donor was his father, who was human leukocyte antigenidentical and had vitiligo. On day 24 after transplant, the patient developedgrade 1 acute graft-versus-host disease, which was controlled over a period of 3months with corticosteroid-induced immunosuppression. Full donor engraftment wasdocumented on day 31 after trans ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

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Auteurs : BOUGUILA J,ROUATBI H,TEJ A,CHABCHOUB I,TRIMECH B,EL AJMI S,ESSOUSSI AS,BOUGHAMMOURA L,

Titre : [Hepatopulmonary syndrome: A complication of type 1 Gaucher disease].

Référence : Rev Pneumol Clin. 2012 Feb;68(1):58-62. doi: 10.1016/j.pneumo.2011.07.002. Epub2011 Oct 13.

Résumé :

Gaucher's disease is a not exceptional lysosomial disease in Tunisia. Type 1 isby far the most common one. Pulmonary involvement is considered to be rare intype 1 Gaucher's disease. Pulmonary hypertension, infiltration of the lungs withGaucher cells, and severe hypoxemia due to intrapulmonary arterial-venous shunts,have been described in case reports and small case series. We reported the caseof hepatopulmonary syndrome in a 14-year-old boy with type 1 Gaucher disease. Thediagnosis of Gaucher di ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

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Auteurs : BOUGUILA J,TEJ A,HASNI I,ESSOUSSI AS,BOUGHAMOURA L,

Titre : [Epstein-Barr virus infection and acute transverse myelitis.]

Référence : Med Mal Infect. 2012 Feb;42(2):83-4. Epub 2012 Jan 21.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : HAMZAOUI A,MAALMI H,BERRAIES A,ABID H,AMMAR J,HAMZAOUI K,

Titre : Transcriptional characteristics of CD4 T cells in young asthmatic children: RORCand FOXP3 axis.

Référence : J Inflamm Res. 2011;4:139-46. Epub 2011 Nov 11.

Résumé :

BACKGROUND: Asthma is a chronic inflammatory disorder, hypothetically caused byautoreactive Th2 cells, whereas Th1 and regulatory T cells may confer protection.The development of Th subpopulations is dependent on the expression oflineage-specific transcription factors. PURPOSE: This study aimed to assess thebalance of CD4(+) T cell populations in asthmatic children. METHODS: Peripheralblood mononuclear cells (PBMC) mRNA expression was assessed in 30 asthmaticchildren (18 patients with mild asthm ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Abderahmane Mami

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Auteurs : KHEMIRI M,BAGAIS A,BEN BECHER S,BOUSNINA S,BAYOUDH F,MEHREZI A,LAKHOUA R,BARSAOUI S,

Titre : Tuberculous Meningitis in Bacille Calmette-Guerin-Vaccinated Children : ClinicalSpectrum and Outcome.

Référence : J Child Neurol. 2012 Jun;27(6):741-6. Epub 2011 Dec 21.

Résumé :

The Bacille Calmette-Guerin vaccination (BCG) contributed widely to reducetuberculosis incidence in developing countries. The aim of this report was toassess the clinical 'spectrum' and outcome of tuberculous meningitis in 16Bacille Calmette-Guerin-vaccinated Tunisian children. They were 9 boys and 7girls aged 2 to 168 months (median 72 months +/- 65.88). Patients presentedmainly with nonspecific symptoms. Neurologic severity was classified as grade I(n = 6) and grade II or III (n = 10). At shor ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KAMEL M,BARKIA A,NASRI M,REBAI T,SAHNOUN Z,KASSIS M,AOUIDET A,

Titre : [Effects of food restriction imposed to adult rats on the bone growth and thehistological structure of the thyroid in their youth.]

Référence : Pathol Biol (Paris). 2012 Oct;60(5):296-300. doi: 10.1016/j.patbio.2011.08.001.Epub 2011 Oct 29.

Résumé :

STUDY PURPOSE: Our objective was the study of the development and the maturationof pups whose mothers were subjected to intermittent fasting. MATERIALS ANDMETHODS: Eight pregnant female Wistar rats were distributed into two groups offour adult females. The rats of the first group were subjected to intermittentfasting beginning on the 14th day of gestation and continued 21 days afterparturition. The rats of the second group were normally fed. The young of bothgroups of rats were sacrificed at the ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Ecole Supérieure des Sciences et Techniques de la Santé de Sfax

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Auteurs : BEN TURKIA H,BEN ROMDHANE M,AZZOUZ H,BEN CHEHIDA A,SLIM ABDELMOULA M,BENABDELAZIZ R,TEBIB N,BEN MESSAOUD M,SAHTOUT S,CHELLY I,ZITOUNA M,MNIF E,BEN DRIDI MF,

Titre : [Rosai-Dorfman disease: Therapeutic issues in 2 cases.]

Référence : Arch Pediatr. 2011 Nov;18(11):1205-9. Epub 2011 Oct 12.

Résumé :

Rosai-Dorfman disease (RDD) is a benign lymphoproliferative disordercharacterized by cervical lymph node enlargement with a consistent risk of airwaycompression and esthetic damage. Extranodal localizations are also described.There is no therapeutic consensus for pediatric forms of RDD. Through 2 pediatriccases with nodal involvement in 1 patient and a sinonasal and soft tissuelocalization in the other, we focus on the management problems of both nodal andextranodal RDD. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

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Auteurs : BOUGUILA J,BRAHIM K,MOKNI M,SKANDRANI K,HARBI A,ESSOUSSI AS,BOUGHAMMOURA L,

Titre : Digestive malacoplakia in children: case report.

Référence : ISRN Gastroenterol. 2011;2011:597350. Epub 2010 Dec 28.

Résumé :

Malacoplakia is a form of chronic granulomatous inflammatory reaction that rarelyaffects the pediatric age group. The gastrointestinal system is the second mostcommon site for the occurrence of malacoplakia. We report the case of a9-year-old girl who was hospitalized for abdominal pain, chronic diarrhea, andrectal hemorrhage. The endoscopic examinations and histopathology confirmed thediagnosis of intestinal malacoplakia. We successfully treated her with orallevofloxacin. This disease does not h ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : CHABCHOUB I,MEJDOUB I,MAALEJ B,ABID D,ALOULOU H,KAMOUN T,KAMOUN S,KARRAY H,HACHICHA M,

Titre : [Congenital rubella still exists in Tunisia!].

Référence : Arch Pediatr. 2011 Nov;18(11):1191-5. Epub 2011 Oct 1.

Résumé :

Congenital rubella syndrome resulting from maternal rubella infection can causeserious multisystemic malformations resulting in severe morbidity and mortality.After immunization, its incidence has been reduced in the developed world, thoughit remains a real problem in developing countries since it causes many handicaps.In Tunisia, despite including rubella immunization in the routine nationalprogram on immunization for girls once they reach the age of 12, the congenitalrubella syndrome still exi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

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Auteurs : AMRI F,HABBOUL Z,TROUDI M,GHRIBI M,GUEDHAMI H,KHATTAT N,

Titre : Primitive Acute polyradiculo-nevritis in child: The Kairouan pediatric departmentexperience. About 22 cases.

Référence : Tunis Med. 2011 Aug-Sep;89(8-9):672-5.

Résumé :

Background: Guillain-Barre Syndrome (GBS) is an acute polyradidulonevritis whichis primitive inflammatory and demyelinisant. It represents the most frequentcause of acute peripheric paralysis of the child. Aim: To study theepidemiologic, clinic, electromyographic, outcome and therapeutic features ofthis disease. Methods: 22 cases of GBS were reported in the pediatric departmentof Ibn El Jazzar's hospital of Kairouan from January 1990 to September 2009.Results: The GBS represents a hospital frequ ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Régional de Kairouan Ibn El Jazzar

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Auteurs : BOUAZIZ ABED A,MUSTAPHA R,CHIHA M,

Titre : [Fortuitous discovery of intracerebral foreign body leads to the diagnosis ofMunchausen syndrome by proxy.]

Référence : Arch Pediatr. 2011 Nov;18(11):1181-4. Epub 2011 Sep 14.

Résumé :

An intracerebral foreign body is a rare situation in childhood. It often occursaccidentally with transorbital or more rarely transnasal penetration. We reportthe case of a child who had been followed since the age of 2.5 months for chronicvomiting without failure to thrive. The fortuitous discovery at 22 months of ageof a 4.5-cm-long sewing needle in his brain probably introduced via the fontanelled us to the diagnosis of Munchausen syndrome by proxy. ...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Nabeul Mohamed Tlatli

____________________________________________________________________________________


Auteurs : BEN ABDALLAH CHABCHOUB R,CHABCHOUB K,MAALOUL I,GARGOURI L,BEN MAHFOUDH K,NABIL MHIRI M,MHIRI R,MAHFOUDH A,

Titre : [Nutcracker syndrome: A rare cause of hematuria.]

Référence : Arch Pediatr. 2011 Nov;18(11):1188-90. Epub 2011 Sep 14.

Résumé :

Nutcracker syndrome is a rare cause of hematuria in children. Clinical signsrelate to compression of the left renal vein between the aorta and the superiormesenteric artery. The diagnosis is suggested on cystoscopy, which revealsunilateral hematuria, and confirmed by imaging. We report the case of a4-year-old child who presented nutcracker syndrome confirmed by CT angiography ofthe abdomen after excluding the other causes of hematuria. Through thisobservation, we emphasize the reality of this sy ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : CHABCHOUB I,KAMOUN F,DAOUED E,BEN MANSOUR L,KMIHA S,KAMOUN T,MNIF Z,HACHICHA M,

Titre : [Aicardi syndrome associated with severe congenital ptosis].

Référence : Arch Pediatr. 2011 Sep;18(9):970-3. Epub 2011 Aug 4.

Résumé :

Aicardi syndrome is a rare neurodevelopmental disorder characterized by corpuscallosum agenesis, chorioretinal lacunae and early-onset infantile spasms. Wereport a particular case of Aicardi syndrome characterized by the association ofthe classical triad of severe bilateral ptosis, pontocerebellar hypoplasia, andperisylvian polymicrogyria in a girl born to non-consanguineous parents, butwhose mother suffered from idiopathic generalized epilepsy. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : KAMOUN T,CHABCHOUB I,AISSA K,BEN MANSOUR L,HACHICHA M,

Titre : [Acute erythroblastopenia due to Parvovirus B19 revealing hereditaryspherocytosis].

Référence : Arch Pediatr. 2011 Sep;18(9):990-2. Epub 2011 Aug 4.

Résumé :

Acute Parvovirus B19 infection is responsible for blocking the erythroblasticline, usually with no consequences on hematopoiesis except in patients withchronic hemolytic anemia in whom it can evolve to potentially serious acuteanemia. We report 2 observations of acute erythroblastopenia revealing hereditaryspherocytosis in 2 children (1 boy and 1 girl) of non-consanguineous parents. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : DHOUIB N,GUEDHAMI H,MELLOULI F,BEN KHALED M,KAABI H,BELHASSEN E,HMIDA S,BEJAOUI M,

Titre : Mycoplasma pneumoniae Associated with Severe Autoimmune Hemolytic Anemia in achild with homozygous beta-thalassemia.

Référence : Tunis Med. 2011 Jul;89(7):652-3.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : BOUZIRI A,HAMDI A,KHALDI A,BEL HADJ S,MENIF K,BEN JABALLAH N,

Titre : Management of meconium aspiration syndrome with Highfrequency oscillatoryventilation.

Référence : Tunis Med. 2011 Jul;89(7):632-7.

Résumé :

Background: High-frequency oscillatory ventilation (HFOV) has been advocated foruse to improve lung inflation while potentially decreasing lung injury. Therewere few data on the early use of HFOV in hypoxemic term neonates. Aim: Toevaluate the effectiveness of HFOV, used as the initial mode of ventilation, inneonates with severe meconium aspiration syndrome (MAS). Methods: In a tertiarycare paediatric intensive care unit, 17 term neonates with severe MAS weremanaged with HFOV, used as the initia ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TAHAR G,RACHID LM,

Titre : Cyclosporine A and steroid therapy in childhood steroid-resistant nephroticsyndrome.

Référence : Int J Nephrol Renovasc Dis. 2010;3:117-21. Epub 2010 Aug 24.

Résumé :

BACKGROUND: In children, idiopathic nephrotic syndrome (INS) is primarily treatedusing corticosteroids. When remission is not achieved, the coadministration ofpotent immunosuppressant therapy becomes imperative. Cyclosporine A (CsA) isreportedly associated with a higher incidence of remission in comparison withother immunosuppressive agents. METHODS: The present study investigated theresponse of combination therapy using CsA and prednisolone in 30 Tunisianchildren with idiopathic steroid-resista ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : CHEMLI J,BOUSSETTA S,KRID S,KAHLOUL N,HASSAYOUN S,ZAKHAMA A,ABROUG S,HACHICHA M,AMRI F,GUEDICHE MN,SFAR MT,ESSOUSSI AS,HARBI A,

Titre : Idiopathic steroid-resistant nephrotic syndrome in child : Study of 20 cases.

Référence : Tunis Med. 2011 Jun;89(6):522-8.

Résumé :

Background: Idiopathic steroid-resistant nephrotic syndrome (ISRNS) is rare andrepresents a significant therapeutic dilemma for paediatricians and paediatricnephrologists. Aim: To analyze characteristics of the ISRNS in the child.Methods: Retrospective study of 20 cases of ISRNS enrolled in paediatricdepartment of nephrology in Sahloul hospital (Tunisia) between June 1993 andDecember 2007 (14 years period). Results: There were eight girls and 12 boys(mean age: 5.8+/- 3.7 years) originating from ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUZIRI A,HAMDI A,BORGI A,BEL HADJ S,FITOURI Z,MENIF K,BEN JABALLAH N,

Titre : Datura stramonium L. poisoning in a geophagous child: a case report.

Référence : Int J Emerg Med. 2011 Jun 15;4(1):31.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHABCHOUB BEN ABDALLAH R,MAALEJ B,ABDELMOULLA S,BOURAOUI A,GARGOURI L,BEN HLIMA N,MAHFOUDH A,

Titre : [Thymoma in children: A report of one case.]

Référence : Arch Pediatr. 2011 Jul;18(7):745-9. Epub 2011 May 18.

Résumé :

BACKGROUND: Thymoma is an uncommon tumor of childhood. It is an anteriormediastinal tumor with few symptoms. The pleura is the most frequent metastaticsite. Surgery is the treatment of choice and the most important prognosticfactors are the stage at initial presentation and whether complete resection canbe performed. CASE REPORT: A 6-year-old girl with no pathological antecedentpresented with a history of prolonged fever. Frontal chest radiography showed alarge mediastinal soft tissue mass with ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN TURKIA H,BEN ROMDHANE M,AZZOUZ H,BEN CHEHIDA A,ABDELMOULA MS,BEN ABDELAZIZ R,TEBIB N,BEN MESSOUD M,SAHTOUT S,CHELLY I,ZITOUNI M,MNIF E,FRANCOISE BEN DRIDI M,

Titre : Rosai -Dorfman disease: A two cases report.

Référence : Tunis Med. 2011 May;89(5):497-501.

Résumé :

Background: Rosai-Dorfman disease (RDD) is a benign lymphoproliferatif disordercharacterized by cervical lymphadenopathies with a consistent risk of airways'compression and esthetical prejudice. Extra nodal localizations are alsodescribed. Aim: To report two pediatric cases of RDD. Cases: the first caseconcerned a patient with a prolonged nodal involvement of RDD. Remission seems tobe natural although it coincided with a sulfamethoxazole- trimethoprime therapy.The second case illustrated an extr ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : GARGAH T,ABIDI K,RAJHI H,BEN ABDALLAH T,CHEBIL M,LAKHOUA MR,

Titre : Vascular complications after pediatric kidney transplantation.

Référence : Tunis Med. 2011 May;89(5):458-61.

Résumé :

Background: Vascular complications, especially those including the renal vein,remain a major cause of lost graft. Aims: To evaluate retrospectively theincidence and management of vascular complications after pediatric renaltransplantation and to assess possible risk factors and their effects on patientand graft. Methods:Atotal of 82 consecutive renal transplants were performed in79 patients at a single institution. The diagnosis of vascular complications wassuspected in the presence of suggestiv ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,SMAOUI H,MENIF K,JABALLAH NB,

Titre : Fatal subdural empyema caused by Streptococcus constellatus and Actinomycesviscosus in a child-case report.

Référence : J Microbiol Immunol Infect. 2011 Oct,44(5):394-6. Epub 2011 Jan 20.

Résumé :

Group milleri streptococci that colonize the mouth and the upper airways aregenerally considered to be commensal. In combination with anaerobics, they arerarely responsible for brain abscesses in patients with certain predisposingfactors. Mortality in such cases is high and complications are frequent. Wepresent a case of fatal subdural empyema caused by Streptococcus constellatus andActinomyces viscosus in a previously healthy 7-year-old girl. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HAMMAMI S,HADDED S,LAJMI K,BESBES LG,MERIEM CB,CHOUCHANE S,GUEDICHE MN,

Titre : Immune thrombocytopenic purpure and coeliac disease.

Référence : J Paediatr Child Health. 2011 Apr;47(4):240. doi:10.1111/j.1440-1754.2011.02052.x.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : BEN TURKIA H,BRAHIM K,AZZOUZ H,TEBIB N,ABDELMOULA MS,BEN CHEHIDA A,FEKIH M,SAYED S,KAABAR N,FRANCOISE BEN DRIDI M,

Titre : Congenital Hyperinsulinism: Review of 12 Tunisian cases.

Référence : Tunis Med. 2011 Apr;89(4):369-73.

Résumé :

Background: Congenital hyperinsulinism in infancy (CHI) is a heterogeneousdisorder with respect to genetics and response to therapy. Data on CHI aresporadic in North African population. Aim: To characterize the clinical featuresand outcome of 12 Tunisian patients with CHI. Methods: data of patients diagnosedwith CHI during the period 1989-2007 were retrospectively analyzed. Diagnosis wasconsidered whenever hyperinsulinemia (3)10mu UI/ml was concomitant tohypoglycemia < 3mmol/l and/or high insuli ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,SIALA N,HAMMI Y,BEN HRIZ M,MAHERZI A,MENIF K,BEN JABALLAH N,

Titre : Chylothorax: a complication of internal jugular vein catheterization in apremature newborn.

Référence : Tunis Med. 2011 Mar;89(3):312-4.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : DHOUIB N,TURKI Z,MELLOULI F,OUEDERNI M,YAHIAOUI S,NAGI S,KOUKI R,BEN SLAMA C,BEJAOUI M,

Titre : Hypocalcaemia due to hypoparathyroidism in B-thalassemia major . A study of a newcase.

Référence : Tunis Med. 2011 Mar;89(3):302-4.

Résumé :

Aim: To report a new case of hypoparathyroidism in a child with ssthalassemiamajor Case: We report a case of a 17-year-old Tunisian girl withtransfusion-dependent thalassemia major presented with paresthesia and pubertaldelay. Laboratory investigations showed hypocalcaemia and hyperphosphatemia.Parathyroid hormone level was low (2 ng/l, normal range: 12-72 ng/l) thanexpected for the degree of hypocalcaemia. Serum ferritin concentration was1770ng/ml. The patient was started on oral daily calcium ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : BEN TURKIA H,YANGUI M,AZZOUZ H,BEN CHEHIDA A,BEN ABELAZIZ R,ABDELMOULA MS,NASRALLAH F,KAABACHI N,WANDERS R,TEBIB N,BEN DRIDI MF,

Titre : Anovel mutation in PEX 26 gene in Zellweger syndrome: a case report.

Référence : Tunis Med. 2011 Mar;89(3):288-91.

Résumé :

Background : Zellweger syndrome is the most severe phenotype of the peroxisomebiogenesis disorders caused by mutations in PEX genes. PEX 1, 6 and 26 genes aremost frequently implicated. Clinical phenotype can't predict the mutated gene.Aim: To report a novel mutation in the PEX 26 gene in infant with typicalZellweger syndrome. Case report: the infant was the second child toconsanguineous parents; the 1st child was dead with neonatal hypotonia. At twomonth of age, we noted a severe hypotonia and ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : GARGAH T,LABESSI A,GOUCHA-LOUZIR R,BEN MOUSSA F,LAKHOUA MR,

Titre : Histopathological spectrum of childhood idiopathic steroid-resistant nephroticsyndrome in Tunisia.

Référence : Tunis Med. 2011 Mar;89(3):258-61.

Résumé :

Background: In children, renal biopsy is routinely required in the management ofidiopathic steroid-resistant nephrotic syndrome particularly prior to startingnephrotoxic immunosuppressive agents. Aim: To investigate the correlationsbetween the results of initial renal biopsy in Tunisian children with idiopathicsteroid-resistant nephrotic syndrome and the subsequent response tocyclosporineprednisolone combination. Methods: We conducted a retrospective studyof children with idiopathic steroid-resi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : GARGAH TT,LAKHOUA MR,

Titre : Mycophenolate mofetil in treatment of childhood steroid-resistant nephroticsyndrome.LID - D66740FE-F05A-407A-A786-F607101E1D6F [pii]

Référence : J Nephrol. 2011 Mar-Apr;24(2):203-7.

Résumé :

Introduction: The literature on the clinical effectiveness of treatments forsteroid-resistant nephrotic syndrome (SRNS) is very limited. The availableevidence suggests a beneficial effect of cyclosporine on remission rates.Mycophenolate mofetil (MMF) represents a promising therapeutic alternativewithout nephrotoxicity. The purpose of the present study was to evaluate theefficacy and tolerance of MMF therapy in children with SRNS. Methods: Sixpatients with SRNS were treated with MMF combined with ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,HAMDI A,BEL HADJ S,BORGI A,MENIF K,BEN JABALLAH N,

Titre : Etat de choc, syndrome de detresse respiratoire aigue et syndrome des loges,causes par une morsure de vipere.

Référence : Tunis Med. 2011 Feb;89(2):217-8.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUZIRI A,BEL HADJ S,KHALDI A,BORGI A,MENIF K,BEN JABALLAH N,

Titre : Early neonatal infection caused by Streptococcus pneumonias: report of 3 cases.

Référence : Tunis Med. 2011 Feb;89(2):206-9.

Résumé :

Background: S pneumoniae is a rare cause (1-8 %) of maternofetal infectioncausing an important morbi-mortality in the newborn and the mother. Aim: Toreport 3 cases of early neonatal infection due to S pneumonia. Cases report :Three cases of early neonatal infection due to S pneumoniae are reported. Thethree newborns were at term or near term babies with a vaginal delivery in twocases and a caesarean section in one case. They presented severe symptoms, with aprogressive onset after birth, leading ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : GARGAH T,KHELIL N,GHARBI Y,KAROUI W,TRABELSI M,RAJHI H,ABDELMOULA J,LAKHOUA MR,

Titre : Primary hyperoxaluria type 1 in Tunisian children.

Référence : Tunis Med. 2011 Feb;89(2):163-7.

Résumé :

Background: Primary hyperoxaliuria type 1 is an autosomalrecessive disordercharacterized by increasing urinary excretion of calcium oxalate, recurrenturolithiasis, nephrocalcinosis, and accumulation of insoluble oxalate throughoutthe body. This inborn error of metabolism appears to be a common cause of endstage renal disease in Tunisia. Aims: To review the clinical, biological andradiological futures of primary hyperoxaluria type 1 and to correlate theseaspects with the development of end-stage ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,HAMDI A,BORGI A,GHORBEL S,KHARFI M,HADJ SB,MENIF K,BEN JABALLAH N,

Titre : Toxic epidermal necrolysis complicated by small bowel intussusception: a casereport.

Référence : J Pediatr Surg. 2011 Feb;46(2):e9-11.

Résumé :

Intestinal involvement in toxic epidermal necrolysis (TEN) has been identifiedonly rarely. We report a case of TEN complicated by small bowel intussusception.The patient was a previously healthy 8-year-old boy who presented with TEN andextensive lesions, including up to 40% of the body surface area as well asconjunctival, oropharyngeal, respiratory, and genital mucosa. Rapidly after theonset of a constant rate of enteral feeding, he developed bilious vomiting,diarrhea, and significant abdominal ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN AYED FF,BEN JEMAA S,GHALI N,KAZDAGHLI K,BEN HASSINE L,KHEMIRI M,BARSAOUI S,

Titre : Hemangioendotheliome hepatique infantile a propos d'une observation.

Référence : Tunis Med. 2011 Jan;89(1):121.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : FEDHILA F,BEN OTHMAN A,REHAIM S,KAZDAGHLI K,KHEMIRI M,OUBICH F,BELLAGHA I,BARSAOUI S,

Titre : Apport de la chimiotherapie dans les gliomes de bas grade de malignite : a proposde 5 cas pediatriques.

Référence : Tunis Med. 2011 Jan;89(1):120.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : FEDHILA F,BEN ROMDHANE M,BEN ROMDHANE K,BELLAGHA I,BARSAOUI S,

Titre : Les tumeurs cervico-faciales de l'enfant. A propos de 8 cas.

Référence : Tunis Med. 2011 Jan;89(1):119.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN AYED F,GHALI N,BEN JEMAA S,CHAOUACHI B,ROMDHANE MB,OUBICH F,BARSAOUI S,

Titre : Le sarcome renal a cellules claires : a propos de deux cas pediatriques.

Référence : Tunis Med. 2011 Jan;89(1):118.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KOUKI R,MELLOULI F,BEJAOUI N,

Titre : Les echanges transfusionnels partiels dans la prise en charge des syndromesdrepanocytaires majeurs compliquees d'accidents vasculaires cerebraux. A proposde 20 cas pediatriques.

Référence : Tunis Med. 2011 Jan;89(1):111.

Résumé :

...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : pas d'institution définie

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,HAMDI A,BEN MASSOUD I,BORGI A,MENIF K,BEN JABALLAH N,

Titre : Multifocal atrial tachycardia: an unusual cause of cardiogenic shock In anewborn.

Référence : Tunis Med. 2011 Jan;89(1):59-61.

Résumé :

Background: Chaotic or multifocal atrial tachycardia (MAT) is a raretachyarrhythmia in children, accounting for less than 1% of supraventriculartachycardia seen in childhood. The majority of children with MAT are healthy; afew may exhibit mild to lifethreatening cardiorespiratory disease. Aim: To reporta new case of MAT revealed by a severe respiratory distress and cardiogenicshock. Case report: We report a rare case of MAT revealed by a severe respiratorydistress and cardiogenic shock in a 12-d ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUKTHIR S,ESSADDAM L,MAZIGH MRAD S,BEN HASSINE L,GANNOUNI S,NESSIB F,BOUAZIZ A,BRINI I,SAMMOUD A,BOUYAHIA O,ZOUARI B,

Titre : Prevalence and risk factors of overweight and obesity in elementaryschoolchildren in the metropolitan region of Tunis, Tunisia.

Référence : Tunis Med. 2011 Jan;89(1):50-4.

Résumé :

Background: Local data about prevalence of obesity in emerging countries arerather scarce. Risk factors for obesity, well known in most industrializedcountries, are poorly understood in Tunisia. Aims: To assess prevalence ofoverweight and obesity and to investigate associations with possible risk factorsin a group of 6-12 year- old schoolchildren in Tunis, Tunisia. Methods:Adescriptive transversal study including a sample of 1335 schoolchildren (6-12years; mean: 9.7 +/- 1.5 years) was conducted ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : ALOULOU H,CHEIKHROUHOU H,BELGUITH N,BEN AMEUR S,BEN MANSOUR L,CHABCHOUB I,KAMMOUN T,HACHICHA M,

Titre : Bardet ' biedl syndrome in the child. A study about 11 cases.

Référence : Tunis Med. 2011 Jan;89(1):31-6.

Résumé :

Background: The syndrome of Bardet-Biedl is definite clinically by theassociation of obesity, polydactyly, pigmentary retinopathy, hypogonadism andbackwardness. Aim: To study the epidemiologic, clinical, biological, genetic,therapeutic and evolutionary characteristic of our patients. Methods: We carriedout a retrospective study concerning 11 hospitalized children and/or follow-upswith the service of pediatry of the CHU Hedi Chaker of Sfax for syndrome ofBardet-Biedl during a period of 21 years ( ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : GARGAH T,LABESSI A,OUNISSI M,DEROUICHE A,CHOKRI Z,TRABELSI M,BEN ABDALLAH T,CHEBIL M,LAKHOUA MR,

Titre : Early infections in children following renal transplantation.

Référence : Tunis Med. 2011 Jan;89(1):26-30.

Résumé :

Background: Infections following renal transplantation in children are a majorcause of severe morbidity and mortality. Surgery is complex and performed in asubject whose immunological mechanisms are impaired by end stage renal failureand immunosuppressive drugs. Aim: To evaluate the incidence and the risk factorsof early infectious following renal transplantation in children. Methods:Infectious complications were retrospectively monitored in 37 children receivingrenal transplantation at our cent ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MAZIGH MRAD S,BEN NASR S,BRINI I,BAHRI A,HAMZAOUI M,BEN KHELIFA S,CHAOUACHI B,SAMOUD GHARBI A,

Titre : Interventional endoscopy in the gastrointestinal tract in children.

Référence : Tunis Med. 2010 Dec;88(12):920-3.

Résumé :

Background : Interventional endoscopic procedures involving the gastrointestinal(GI) tract in children are very common. Over the last several years the number ofprocedures in this area has steadily increased. Aim: To study indications andresults of GI interventional endoscopies performed in a Pediatric GI unit.Methods: Retrospective study over a period of 10 years (1999- 2008). Data werecollected from endoscopic files. All procedures were performed endoscopicallyunder general anesthesia. Results ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUSNINA S,KHARFI M,BEN HASSINE D,BOUSSETTA K,TINSA F,

Titre : Congenital cutaneous candidiasis associated with respiratory distress in afull-term newborn.

Référence : Tunis Med. 2010 Nov;88(11):844-6.

Résumé :

Background: Congenital candidiasis is rare occurring in most cases in prematureand low birth weight new born. It can produce a spectrum of disease ranging froma diffuse skin eruption to a severe systemic disease with or without skininvolvement. Amphotericin B is the first-line agent for the treatment of systemicdisease. Aim: To describe a congenital candidiasis in a full-term new born. Casereport: At birth, the newborn had a generalized, erythematous, papulovesiculareruption. He was treated by t ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HACHICHA M,MNIF Z,KAMMOUN T,ALOULOU H,BOUKEDI A,SFAIHI L,

Titre : [Hypoplasia of the internal carotid artery: A rare cause of cerebral ischemicstroke in children.]

Référence : Arch Pediatr. 2010 Dec;17(12):1657-60. Epub 2010 Oct 30.

Résumé :

Hypoplasia of the carotid arteries is a rare congenital anomaly which, whensymptomatic, presents as cerebral ischemia or hemorrhage. We report a case ofhypoplasia of the carotid arteries revealed by cerebral ischemic stroke in aninfant with hereditary spherocytosis. The diagnosis was confirmed by MRangiography. We describe this rare cause of stroke in children and thecharacteristics of its association with hereditary spherocytosis. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : HACHICHA M,BOUDAWARA T,KAMOUN T,MAALEJ B,MEJDOUB I,AYADI L,CHABCHOUB I,

Titre : [Alopecia, congenital ichthyosis, and growth delay, what is the diagnosis?]

Référence : Arch Pediatr. 2010 Dec;17(12):1685-6, 1725-7. Epub 2010 Oct 30.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : GHEDIRA BESBES L,HADDAD S,BEN MERIEM C,GOLLI M,NAJJAR MF,GUEDICHE MN,

Titre : Infantile scurvy: two case reports.

Référence : Int J Pediatr. 2010;2010:717518. Epub 2010 Sep 29.

Résumé :

Background. Ascorbic acid (vitamin C) is necessary for the formation of collagen,reducing free radicals, and aiding in iron absorption. SCURVY, a disease ofdietary ascorbic acid deficiency, is uncommon today. It still exists in high riskgroups including economically disadvantaged populations with poor nutrition. Theincidence of SCURVY in the pediatric population is very low. Cases Report. Herewe report two cases of SCURVY revealed by subperiosteal hematoma in children withcerebral palsy and deve ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : BEJAOUI M,HASSEN AB,HMIDA S,HAMED LB,MAAMER M,BARBOUCHE R,KSOURI H,MELLOULI F,

Titre : Successful treatment of fusarium solani ecthyma gangrenosum in a patient affectedby leukocyte adhesion deficiency type 1 with granulocytes transfusions.

Référence : BMC Dermatol. 2010 Oct 7;10:10.

Résumé :

BACKGROUND: Ecthyma gangrenosum (EG) manifests as a skin lesion affectingpatients suffering extreme neutropenia and is commonly associated withPseudomonas aeruginosa in immunocompromised patients. Leukocyte adhesiondeficiency I (LAD I) which count among primary immunodeficiency syndromes of theinnate immunity, is an autosomal recessive disorder characterized in its severephenotype by a complete defect in CD18 expression on neutrophils, delayed cordseparation, chronic skin ulcers mainly due to re ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : GARGAH T,GHARBI Y,BEN MOUSSA M,LAKHOUA MR,

Titre : [Uropathies and nephropathies of Bardet-Biedl syndrome in children].

Référence : Tunis Med. 2010 Oct;88(10):737-41.

Résumé :

BACKGROUND: The Bardet-Biedl syndrome is an autosomal recessive disease,characterised by obesity, retinal degeneration, hypogenitalism in men,polydactylism and an often moderate mental retardation. With these cardinalfeatures, others clinical findings (secondary features) including diabetes,congenital heart defects, hypertension or syndactyly can be seen. Renalinvolvement is almost constant, but varies from a moderate impairment of thetubular functions to chronic renal failure caused by malforma ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : ALOULOU H,BEN THABET A,KHANFIR S,BEN MANSOUR L,CHABCHOUB I,LABRUNE P,KAMMOUN T,HACHICHA M,

Titre : [Type I Crigler Najjar syndrome in Tunisia: a study of 30 cases].

Référence : Tunis Med. 2010 Oct;88(10):707-9.

Résumé :

BACKGROUND: Crigler-Najjar syndrome is a rare metabolic disorder characterized bysevere unconjugated hyperbilirubinemia resulting in deficiency of bilirubinuridine diphosphate (UDP) glucuronosyltransferase activity in the liver. AIM: Tostudy the clinical, genetic therapeutic aspects and the outcome of Crigler Najjartype 1 in Tunisia. METHODS: This is a retrospective report of Crigler Najjarcases who were hospitalised in pediatric department of Hedi Chaker hospitalduring 21 years (from 1st Januar ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUGUILA J,CHABCHOUB I,MONCEF Y,MLIKA A,SAGHROUNI F,BOUGHAMOURA L,ESSOUSSI AS,

Titre : [Treatment of severe hemophagocytic syndrome associated with visceralleishmaniasis].

Référence : Arch Pediatr. 2010 Nov;17(11):1566-70. Epub 2010 Sep 28.

Résumé :

The association of hemophagocytic syndrome (HS) and visceral leishmaniasis is afrequent disorder during infancy in endemic areas such as Tunisia. The range ofseverity of HS secondary to visceral leishmaniasis includes both pure biologicalforms that resolve with antimicrobial therapy and life-threatening emergenciesthat require specific treatment. We describe 2 cases of severe HS secondary tovisceral leishmaniasis. The diagnosis of HS was based on the HLH-2004 diagnosticcriteria. Therapy involved ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : LAKHOUA MR,GOUCHA-LOUZIR R,GARGAH T,

Titre : [Interest of mycophenolate mofetil in children with membranous lupus nephritis.]

Référence : Nephrol Ther. 2010 Dec;6(7):564-8. Epub 2010 Sep 15.

Résumé :

The management of lupus nephritis remains a clinical problem in children as inadults. Corticosteroids, cyclophosphamide and azathioprine have been used withsatisfactory response, but the most important problems are their potentialtoxicities. Therefore, we evaluate the use of mycophenolate mofetil (MMF) as anew agent for treatment of lupus nephritis in children. Five children withbiopsy-proven proliferative glomerulonephritis with active lesions received MMF,combined with corticosteroids during t ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : LAKHOUA RM,GHARBI Y,GOUCHA-LOUZIR R,GARGAH T,

Titre : Reversible nephrotic syndrome secondary to pulmonary hydatid disease.

Référence : S Afr Med J. 2010 Jul 2;100(7):424-5.

Résumé :

Most patients with pulmonary hydatidosis are children. The disease may beasymptomatic or revealed by unusual events such as a glomerulopathy. An8-year-old boy from a rural part of Tunisia presented with generalised oedema andmacroscopic haematuria. There was no familial history of renal disease. He had anormal blood pressure (100/60 mmHg), and a pleural effusion was detected.Urinalysis showed nephrotic range proteinuria (375 mg/kg/d) and microscopichaematuria. His serum total protein concentrati ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MATOUSSI N,BELHADJ A,MAMMOU S,DLALA SB,HELAYEM M,ROCCHICCIOLI F,BOUZAIDI S,ABDENNEBI M,

Titre : [Abnormal intestinal permeability in children with autism].

Référence : Tunis Med. 2010 Sep;88(9):685-6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : LAKHOUA MR,GHARBI Y,LABESSI A,GARGAH T,

Titre : [Urinary tract infections in children following renal transplantation: asingle-center experience].

Référence : Tunis Med. 2010 Sep;88(9):638-41.

Résumé :

BACKGROUND: Urinary tract infection (UTI) is the most common complication afterkidney transplantation and represents a potential life-threatening risk for theimmunocompromised child. AIM: The aim of this report is to determinate incidence,risk factors, microbiologic features and evaluate the impact of this complicationon graft outcome and patient mortality. METHODS: We performed a retrospectivecohort study reviewing the medical records of 17 children from 38 who received arenal transplant in our ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : GUEDICHE MN,BEN MERIEM C,CHOUCHENE S,HAMMAMI S,BOUAFSOUN C,GHEDIRA-BESBES L,HADDAD S,

Titre : Nail-patella syndrome associated with short stature: a case series.LID - 869470 [pii]

Référence : Case Report Med. 2010;2010. pii: 869470. Epub 2010 Aug 8.

Résumé :

Introduction. Nail-patella syndrome (NPS) is a rare genetic disorder that ischaracterized by a pleiotropic malformation affecting the nail, the skeleton, andoccasionally the central nervous system and the kidneys. Case Presentation. Wereport two paediatric cases, which are of two sisters, who aged, respectively,two and five years. They are admitted to explore short stature. The initialclinical examination and radiologic findings confirmed the diagnosis ofNail-patella syndrome. Conclusion. Skelet ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : BOUZIRI A,HAMDI A,KHALDI A,SMAOUI H,KECHRID A,MENIF K,BEN JABALLAH N,

Titre : [Malignant pertussis: an underdiagnosed illness]

Référence : Med Trop (Mars). 2010 Jun;70(3):245-8.

Résumé :

PURPOSE: Malignant pertussis is a rare life-threatening illness characterized bysevere respiratory failure, severe leukocytosis, and pulmonary hypertension. Thepurpose of this study was to determine the prevalence of malignant pertussis ininfants admitted to a pediatric intensive care unit (PICU) for severe acuterespiratory failure associated with severe leukocytosis. METHODS: Thisretrospective study was based on review of the medical charts of infants agedless than 3 months admitted to the PICU ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MELLOULI F,KSOURI H,LAKHAL A,TORJMEN L,ABDELKEFI A,LADEB S,HMIDA S,OTHMAN TB,BEJAOUI M,

Titre : Switch from beta-thalassemia major to beta-thalassemia intermedia after secondarygraft failure.

Référence : Exp Clin Transplant. 2010 Sep;8(3):269-71.

Résumé :

In this article, we report a switch of beta-thalassemia major to intermediabeta-thalassemia after allogeneic bone marrow transplant of a 6-year-old girlfrom her HLA-matched brother. After stable mixed chimerism, the patient had asecondary graft rejection and returned to total recipient chimerism as assessedby real-time polymerase chain reaction assay. Nonetheless, with a mediumhemoglobin rate of 89 g/L, she did not need further transfusions for 60 monthsafter rejection. We conclude that complete ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : BOUSSETTA K,TINSA F,GHAFFARI H,BRINI I,ALOUI N,JAUBERT F,BOUSNINA S,

Titre : Mediastina Tuberculosisl mass in a three-month-old boy.

Référence : Tunis Med. 2010 Aug;88(8):602-4.

Résumé :

Background: Mediastinal mass of tuberculous origin is exceedingly rare in infant.Aim: to report an exceedingly rare case of mediastinal mass of tuberculousorigin. Case report: We report a three-month-old boy who presented a one monthhistory of wheezing and persistent pneumopathy. Radiological investigationsshowed a large posterior mediastinal mass which infiltrates lungs. Thoracoscopicbiopsy showed caseous necrosis with granuloma suggestive of tuberculosis. Theoutcome was favourable with antitub ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : LAKHOUA MR,KAABAR N,BEN MOUSSA M,GHARBI Y,GARGAH T,

Titre : [Posterior uretral valves. About a series of 44 cases].

Référence : Tunis Med. 2010 Aug;88(8):557-62.

Résumé :

OBJECTIF: To explore the physical symptoms and radiological findings for thediagnosis of posterior urethral valves (PUV), to point of the therapeutic snagsdepending on gravity and delay of lesions. METHODS: We reviewed the records of 44patients with PUV. Mean age: 2 years 1/2 (range 1 day-13 years). More than 75% ofpatients were less than 2 years old. RESULTS: In utero diagnosis was made in 8patients (14%). After birth, the diagnosis was based on urological signs (asfrequent as diagnosis is made ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : TINSA F,BOUSSETTA K,BOUSNINA S,MENIF K,NOUIRA F,HAOUET S,SAHTOUT S,

Titre : Congenital salivary gland anlage tumor of the nasopharynx.

Référence : Fetal Pediatr Pathol. 2010;29(5):323-9.

Résumé :

Nasal and upper respiratory tract obstruction in the neonatal period can resultfrom a variety of conditions, and may be present with variable symptoms. Salivarygland anlage tumor, also referred as congenital pleomorphic adenoma, is a veryrare benign congenital tumor of the nasopharynx, which may produce nasalobstruction and other associated, nonspecific symptoms. We report a case ofcongenital salivary gland anlage tumor causing a severe neonatal respiratorydistress with pulmonary hypertension. T ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TRABELSI A,FODHA I,CHOUIKHA A,BEN HADJ FREDJ M,MASTOURI M,ABDELAZIZ AB,SFAR T,ESSOUSSI AS,JAOUA S,STEELE AD,

Titre : Rotavirus strain diversity in the Centre Coast of Tunisia from 2000 through 2003.

Référence : J Infect Dis. 2010 Sep 1;202 Suppl:S252-7.

Résumé :

An epidemiological survey investigating rotavirus infection in children wasundertaken in the coastal region of Tunisia from January 2000 through September2003. A total of 309 fecal specimens were screened by enzyme-linked immunosorbentassay and latex agglutination assay for the presence of group A rotavirusantigen. The detection rate was 26.2%. Rotavirus outbreaks showed atemperature-dependant pattern (P = .026) but no significant association withrainfall. Rotavirus strains isolated were analyze ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

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Auteurs : GARGAH T,HARRATH MB,BACHROUCHE H,RAJHI H,ABDALLAH TB,LAKHOUA MR,

Titre : First case of childhood Takayasu arteritis with renal artery aneurysms.

Référence : Pediatr Rheumatol Online J. 2010 Jul 24;8:21.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : CHEMLI J,HASSAYOUN S,KETATA S,AJMI H,AYECHE H,ZOUARI N,ABROUG S,BOUJAAFAR N,HARBI A,

Titre : [Kawasaki disease and Mycoplasma pneumoniae infection.]

Référence : Med Mal Infect. 2010 Dec;40(12):717-9. Epub 2010 Jul 21.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : HADDAD S,GHEDIRA-BESBES L,LAJMI K,HAMMAMI S,CHOUCHENE S,BEN MERIEM C,GUEDICHE MN,

Titre : [Lower-limb arterial thrombosis in a relapse of nephrotic syndrome.]

Référence : Arch Pediatr. 2010 Sep;17(9):1317-9. Epub 2010 Jul 17.

Résumé :

INTRODUCTION: Venous thromboembolic complications are well-known in patients withnephrotic syndrome. Arterial thrombosis has rarely been reported and is mainlyobserved in adults. CASE REPORT: A 9-year-old patient with a history ofsteroid-dependent nephrotic syndrome was admitted after foot trauma. He presentedwith severe pain in his right foot, which was cold and mottled, with reducedsensation and motor activity. No pulse was palpable in his right foot. Doppler'sultrasonography confirmed the thr ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : BOUZIRI A,HAMDI A,MENIF K,BEN JABALLAH N,

Titre : Hepatorenal injury induced by cutaneous application of Atractylis gummifera L.

Référence : Clin Toxicol (Phila). 2010 Aug;48(7):752-4.

Résumé :

Introduction. In Mediterranean countries, intoxication by Atractylis gummifera L.is frequent and characterized principally by hepatorenal injury, often fatal. Itstoxicity after a cutaneous application is unknown. We report a case of poisoningby A. gummifera L. induced by repeated cutaneous application. Case report. A30-month-old boy was admitted in our pediatric intensive care unit in coma(Glasgow Coma Scale 8). Investigations showed hepatic cellular injury,cholestasis, decreased prothrombin lev ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,LOUATI H,MENIF K,KHAYATI A,BEN JABALLAH N,

Titre : Respiratory failure revealing a multilocular thymic cyst in an infant.

Référence : Ann Thorac Surg. 2010 Jul;90(1):305-8.

Résumé :

Multilocular thymic cysts are rare benign acquired lesions of the neck andmediastinum. In children, multilocular thymic cysts are usually symptomatic afterthe age of 2 years and produce few symptoms. We report an unusual case of amultilocular thymic cyst diagnosed in a 3-month-old girl, causing severerespiratory failure. We believe that this unusual presentation has not beenpreviously reported in the literature. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHABCHOUB BEN ABDALLAH R,TRABELSI L,BEN AMEUR S,KAMMOUN F,BOUKEDI A,BEN SALAH M,BEN HLIMA N,MAHFOUDH A,

Titre : [Use of recombinant factor VII in Glanzmann thrombasthenia: A case report.]

Référence : Arch Pediatr. 2010 Jul;17(7):1062-4. Epub 2010 Jun 8.

Résumé :

Glanzmann thrombasthenia (TG) is a congenital platelet function disordercharacterized by frequent and occasionally severe bleeding events. Treatment isbased on platelet transfusion at the time of bleeding. We report a case of GTrevealed in the neonatal period, a severe hemorrhagic syndrome refractory totransfusions, treated at the age of 6 years. Activated recombinant factor VII(Novoseven((R))) injections were necessary. The advantages of recombinantactivated factor VII in GT patients with plate ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : CHABBCHOUB BEN ABDALLAH R,KAMMOUN F,AYEDI M,TRABELSI L,BEN SALAH M,BEN HLIMA N,MAHFOUDH A,

Titre : [Multiple cerebral cavernomatosis in a 1-year-old child.]

Référence : Arch Pediatr. 2010 Aug;17(8):1156-8. Epub 2010 Jun 9.

Résumé :

Cavernous malformations are vascular lesions of the central nervous system. Theyare very rare in childhood. We report the case of sporadic cavernous cerebralangioma in a 1-year-old girl without pathologic antecedents revealed by a partialseizure. With this case and a review of the literature, we show the clinical andtherapeutic characteristics of cerebral cavernomatosis in childhood. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : DHOUIB N,MELLOULI F,OUEDERNI M,YAHIAOUI S,GUERMAZI S,NAGI S,BEJAOUI M,

Titre : Early onset of cerebrovascular accident in a thalassemia major child.

Référence : Tunis Med. 2010 May;88(5):372.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : TINSA F,YAHYAOUI S,JALLOULI M,BOUSNINA D,SLIM I,ZOUARI B,BOUSSETTA K,BOUSNINA S,

Titre : Laryngotracheobronchial foreign body in children: predictive factors ofrespiratory sequelae.

Référence : Tunis Med. 2010 May;88(5):330-4.

Résumé :

Background : Inhalation of laryngotracheobronchial foreign body in children is aserious accident that may compromise the prognosis of the child and therespiratory function in the long term. Aim: identify the predictive factors ofrespiratory sequelae of laryngotracheobronchial foreign body inhalation. Methods:This retrospective study was conducted in the children hospital of Tunis during aperiod of nine years (2000 - 2008). In all statistical tests, the significancelevel was set at 0.05. Results ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : JMAL A,BOUYAHYA O,AYADI I,OCCHI H,FEKI M,KAABACHI N,SAMMOUD A,ABDENNEBI M,BOUKTHIR S,

Titre : Variation des concentrations seriques de leptine chez l'enfant tunisien nonobese.

Référence : Ann Biol Clin (Paris). 2010 May-Jun;68(3):311-5.

Résumé :

Leptin, an adipocyte-derived peptide hormone, is thought to play a key role inthe regulation of body fat mass. Beyond this function, it appears to be anintegral component of various hypothalamo-pituitary-endocrine feedback loops.Because childhood and puberty are periods of major metabolic and endocrinechanges, we investigated leptin levels in 348 non overweight, non obese children(147 boys, 201 girls, age: 6-12 years) and then correlated these levels with age,anthropometric data, pubertal stage ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Faculté de Médecine de Tunis

____________________________________________________________________________________


Auteurs : TINSA F,YAHYAOUI S,BRINI I,MICHEL-CALEMARD L,BOUSSETTA K,BOUSNINA S,

Titre : [Recessive autosomic polycystic kidney in a Tunisian family: correlation betweengenotype and phenotype?]

Référence : Tunis Med. 2010 Jan;88(1):68-9.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,KARBOUL L,CHEKIB J,HAMOUDA S,BEN JEMAA L,BOUSSETTA K,BOUSNINA S,

Titre : Marfan syndrome in a Triple-X girl: a new association?

Référence : Tunis Med. 2010 Mar;88(3):203-6.

Résumé :

BACKGROUND: Triple X is a sex chromosomal abnormality that involves the presenceof three sex chromosomes resulting in 47, XXX karyotype. Most patients sufferingfrom this syndrome are usually mentally normal or subnormal with no grossmalformation. AIM: to ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,EL GHARBI A,NCIBI N,BOUGUERRA C,BEN AISSIA W,ZOUARI B,BOUSSETTA K,BOUSNINA S,

Titre : [Utility of lumbar puncture for febrile seizure among infant under one year old]

Référence : Tunis Med. 2010 Mar;88(3):178-83.

Résumé :

BACKGROUND: Febrile seizure is a frequent cause of hospitalization. Itsmanagement remains problematic. According to the American Academy of Pediatrics,lumbar puncture, which is not devoid of risk, is strongly recommended in infantsunder 1 year. AIM: to de ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN TURKIA H,RIAHI I,AZZOUZ H,LADAB S,CHERIF W,BEN CHEHIDA A,ABDELMOULA MS,CAILLAUD C,CHEMLI J,ABDELHAK S,TEBIB N,BEN DRIDI MF,

Titre : [Phenotype and mutational spectrum in Tunisian pediatric gaucher disease]

Référence : Tunis Med. 2010 Mar;88(3):158-62.

Résumé :

BACKGROUND: Gaucher disease (GD) is a sphingolipidosis with heterogeneousphenotypic expression. The vital and / or functional prognosis may be threatenedby an early visceral severe involvement in type 1 or a neurological degenerationin the more rarest neu ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : DHOUIB N,TURKI Z,MELLOULI F,OUEDERNI M,YAHIAOUI S,NAGI S,BEN SLAMA C,BEJAOUI M,

Titre : Efficacy of metformin in the treatment of diabetes mellitus complicatingthalassemia major.

Référence : Tunis Med. 2010 Feb;88(2):136.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,MENIF K,BEN JABALLAH N,

Titre : [Acute disseminated encephalomyelitis associated with Mycoplasma pneumoniaeinfection in children 2 case reports]

Référence : Tunis Med. 2010 Feb;88(2):125-8.

Résumé :

BACKGROUND: Extrapulmonary complications of Mycoplasma pneumoniae infection arerare and dominated by nervous system disorders. Two patients suffering from acutedisseminated encephalomyelitis associated with M. Pneumoniae infection arereported. AIM: Report ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUZIRI A,KHALDI A,MENIF K,BEN JABALLAH N,

Titre : Unusual cause of severe toxic methemoglobinemia in an infant: a case report.

Référence : Int J Emerg Med. 2010 Feb 27;3(1):57-9.

Résumé :

Toxic methemoglobinemia is an uncommon blood disorder induced by exposure tocertain oxidizing agents and drugs. In severe cases, this condition may rapidlylead to major cardiopulmonary compromise and constitutes an emergency requiringprompt recognition an ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,ESSADDAM L,FITOURI Z,BRINI I,DOUIRA W,BECHER SB,BOUSSETTA K,BOUSNINA S,

Titre : Abdominal Tuberculosis in Children.

Référence : J Pediatr Gastroenterol Nutr. 2010 Jun;50(6):634-8.

Résumé :

BACKGROUND:: Abdominal tuberculosis (TB) includes infection of thegastrointestinal tract, peritoneum, mesentery, abdominal lymph nodes, liver,spleen, and pancreas. The most common forms of abdominal TB in children areadhesive peritonitis and nodal disease ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHABCHOUB I,MAALEJ B,TURKI H,ALOULOU H,AISSA K,BEN MANSOUR L,KAMOUN T,HACHICHA M,

Titre : [Cholelithiasis associated with portal cavernoma in children: 2 case reports]

Référence : Arch Pediatr. 2010 May;17(5):507-10. Epub 2010 Mar 19.

Résumé :

The association of cholelithiasis and portal cavernoma is rarely described inadult or pediatric patients. We report 2 cases of gallstone associated withportal cavernoma in 2 girls. The first one suffered from Evans syndromeassociated with congenital immun ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : GARGAH T,ESSID A,LABASSI A,HAMZAOUI M,LAKHOUA MR,

Titre : Xanthine urolithiasis.

Référence : Saudi J Kidney Dis Transpl. 2010 Mar;21(2):328-31.

Résumé :

Hereditary xanthinuria type I, a defect of purine metabolism, results from agenetic deficiency of xanthine oxidase. It is an uncommon cause of stoneformation in children. We report here two children with xanthine urolithiasis.The first patient was an 8-ye ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : TINSA F,BELLALAH M,BRINI I,BOUSNINA D,LEHMANN A,BOUSSETTA K,BOUSNINA S,

Titre : Infantile onset of Cockayne syndrome without photosensitivity in a Tunisian girl.

Référence : Tunis Med. 2009 Dec;87(12):877-9.

Résumé :

BACKGROUND: Cockayne syndrome is a rare autosomal recessive disorder with dwarfism, mental retardation, and otherwise clinically heterogeneous features. Classically, the onset of Cockayne syndrome starts in the second year of life. The failure of RNA synthesis to recover to normal rates after UV-C irradiation provides a useful diagnostic test and the clinical feature that correlates most strongly with defective RNA synthesis is photosensitivity. AIM: To report an unusual case of Cockayne Syndrom ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,BOUSSETTA K,GHARBI A,BOUSNINA D,ABDELAZIZ R,BRINI I,BOUSNINA S,

Titre : [Community acquired pneumonia in children]

Référence : Tunis Med. 2009 Dec;87(12):851-6.

Résumé :

BACKGROUND: Community acquired pneumonia is responsible for a high morbidity in children. The etiological diagnosis is not always easy and treatment remains probabilistic. AIM: To analysis clinical patterns and the outcome of community acquired pneumonia and to find arguments in favour of its origin. METHODS: A prospective analysis of the files of 39 children (20 boys, 19 girls) hospitalized between (1 december 2004 - 30 june 2005) for community acquired pneumonia was performed. Included dchildr ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,SIALA N,NCIBI N,FETNI I,KASDALLI K,BEN JBALLAH N,MEHREZI A,

Titre : Pneumococcal infection and haemolytic uremic syndrome.

Référence : Tunis Med. 2009 Nov;87(11):790-2.

Résumé :

BACKGROUND: Hemolytic uremic syndrome, one of the common causes of acute renal failure in children, is characterized by the triad of microangiopathy, haemolytic anemia, thrombocytopenia and acute renal failure. The diarrhoea-associated Hemolytic uremic syndrome is usually termed as a typical Hemolytic uremic syndrome. Streptococcus pneumoniae is an uncommon etiological pathogen for inducing Hemolytic uremic syndrome, and Streptococcus pneumoniae associated Hemolytic uremic syndrome is also terme ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN TURKIA H,TEBIB N,AZZOUZ H,ABDELMOULA MS,BEN CHEHIDA A,CHEMLI J,MONASTIRI K,CHAABOUNI M,SANHAGI H,ZOUARI B,KAABACHI N,BEN DRIDI MF,

Titre : Incidence of the mucopolysaccharidoses in Tunisia.

Référence : Tunis Med. 2009 Nov;87(11):782-5.

Résumé :

BACKGROUND: The mucopolysaccharidoses (MPS) are a devastating heterogenous group of lysosomal storage disorders. AIM: To evaluate the epidemiological profile of MPS in Tunisia. METHODS: we conducted a retrospective epidemiological survey covering the period 1970-2005. Multiple sources were used to identify affected patients. RESULTS: Ninety six confirmed MPS cases were collected from 132 suspected cases found in the surveyed data. Of the ninety six confirmed cases, 20% were from multiplex famili ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : CHABCHOUB I,BOUKEDI A,TURKI H,ALOULOU H,KAMOUN T,HACHICHA M,

Titre : [Jarcho-Levin syndrome: Report on one case.]

Référence : Arch Pediatr. 2010 Apr;17(4):426-8. Epub 2010 Feb 26.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : TINSA F,ESSADDAM L,FITOURI Z,NOUIRA F,DOUIRA W,BEN BECHER S,BOUSSETTA K,BOUSNINA S,

Titre : Extra-pulmonary tuberculosis in children: a study of 41 cases.

Référence : Tunis Med. 2009 Oct;87(10):693-8.

Résumé :

BACKGROUND: Extrapulmonary tuberculosis accounts for up to one third of all casesof tuberculosis and children show a higher predisposition to the development ofextra-pulmonary tuberculosis. AIM: To review the clinical features of theextrapulmonary tuberculosis in children. METHODS: forty one children withextrapulmonary tuberculosis followed in the Children Hospital of Tunis betweenJanuary 1995 and December 2007 were reviewed. RESULTS: Extrapulmonarytuberculosis constitutes 57.9% of all cases of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,BRINI I,YAHYAOUI S,BOUSENNA O,BOUSETTA K,TRABELSI A,BOUSNINA S,

Titre : [Infectious diarrhoea in children under five years]

Référence : Tunis Med. 2009 Sep;87(9):599-602.

Résumé :

AIM: to determine the prevalence of rotavirus in acute diarrhea among childrenunder 5 years and to describe the epidemiology, clinical trials of rotavirusdiarrhea and compare them with those of other gastroenteritis. METHODS: AProspective study during 1 year (1 January 2007-31 December 2007) was conductedin the department of Pediatrics B of the Children's Hospital of Tunis. 117children aged under than 5 years and admitted for acute community gastroenteritiswere included in the study. A search of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KAHLOUL N,ADOUANI M,KHATTAT N,ALLANI H,KRICHEN I,ZAKHAMA A,AMRI F,

Titre : [Fetus in fetu: A case report.]

Référence : Arch Pediatr. 2010 Mar;17(3):249-52. Epub 2010 Jan 29.

Résumé :

Fetus in fetu is an abnormality secondary to abnormal embryogenesis in adiamniotic, monochorionic pregnancy. It is a rare pathological condition andfewer than 100 cases have been reported in the literature. We report a neonatalcase which occurred in a girl who had been hospitalized since birth because of anabdominal mass. A conventional radiograph of the abdomen revealed a right masscontaining calcifications, which displaced intestinal structures to the left.Abdominal ultrasonography and CT scan ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Régional de Kairouan Ibn El Jazzar

____________________________________________________________________________________


Auteurs : ASMA B,AMMAR K,KHALED M,NAJOUA G,NEJLA BJ,

Titre : Acute respiratory failure revealing a multilocular thymic cyst in an infant: acase report.

Référence : Cases J. 2009 Nov 30;2:9109.

Résumé :

INTRODUCTION: Multilocular thymic cysts are rare benign lesions of the neck andmediastinum that can occur at any age. In children, multilocular thymic cysts areusually symptomatic after the age of 2 years and produce few symptoms. We presentan unusual case of a multilocular thymic cyst diagnosed in a 3-month-old girl andcausing severe respiratory failure. CASE PRESENTATION: A 3 month-old-girl, with amedical history of dyspnea and wheezing since the age of 20 days, presented inour pediatric inten ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUYAHIA O,KHELIFI I,GHARSALLAH L,HARZALLAH K,MRAD SM,GHARGAH T,BOUKTHIR S,AZZA SEL G,

Titre : Nephrotic syndrome and Guillan-Barre Syndrome: a rare association in child.

Référence : Saudi J Kidney Dis Transpl. 2010 Jan;21(1):135-7.

Résumé :

Only few cases of nephrotic syndrome associated with Guillain-Barre Syndrome(GBS) have been reported in the adult and pediatric literature. A 3-year-old boywas initially admitted to our hospital following five days of progressiveweakness of his extremitie ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,ESSADDAM L,FITOURI Z,BOUSSETTA K,BEN BECHER S,BOUSNINA S,

Titre : Central system nervous tuberculosis in infants.

Référence : J Child Neurol. 2010 Jan;25(1):102-6.

Résumé :

The lack of specific symptoms and signs in patients with tuberculous meningitismakes early diagnosis difficult. In this report, we reviewed the clinicalfeatures and laboratory findings of 6 infants with central system nervoustuberculosis during a 10-year ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,KHALDI F,HAMZAOUI A,CHAOUACHI B,HAMZAOUI M,BEN BECHER S,BELLAGHA I,BARSAOUI S,

Titre : [Cystic pulmonary malformations: Clinical and radiological polymorphism. A reporton 30 cases.]

Référence : Rev Pneumol Clin. 2009 Dec;65(6):333-40. Epub 2009 Oct 30.

Résumé :

OBJECTIVES: This report describes different clinical pictures of cystic pulmonarymalformation (CPM) and problems in diagnosis. PATIENTS AND METHODS: Cases of CPMbetween 01 January 1994 and 31 December 2004 diagnosed in our institution werereviewed. RESULTS: Thirty-three cases of CPM were diagnosed in 30 children. Theyconsisted of 17 boys and 13 girls ranging from 20 days to 16 years of age at thetime of the diagnosis. The CPM included: 17 cases of congenital lobar emphysema(CLE), seven bronchoge ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN TURKIA H,AZZOUZ H,TEBIB N,ABDELMOULA MS,BEN CHEHIDA A,HLEL Y,CAILLAUD C,SAHLI H,BEN DRIDI MF,

Titre : [Enzyme replacement therapy for Gaucher paediatric disease: the only Tunisianexperience]

Référence : Tunis Med. 2009 May;87(5):344-8.

Résumé :

AIM: We report through the first Tunisian experience with enzyme replacementtherapy, the goals and consensus recommendations for treatment and monitoring ofpaediatric non neuronopathic Gaucher disease. METHODS: Three children withGaucher disease undergone enzyme replacement therapy with Cerezyme for severevisceral and/or bone involvement. Visceral, hematologic, bone, and growthparameters were assessed initially and under treatment. RESULTS: Two childrenpresented with severe visceral or hematolog ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BOUYAHIA O,OUDERNI M,BEN MANSOUR F,MATOUSSI N,KHALDI F,

Titre : Diabetic acido-ketosis revealing thiamine-responsive megaloblastic anemia.

Référence : Ann Endocrinol (Paris). 2009 Dec;70(6):477-9. Epub 2009 Nov 18.

Résumé :

Thiamine-responsive megaloblastic anemia (TRMA) is a rare autosomal recessivedisorder characterized by megaloblastic anemia, diabetes mellitus and progressivesensorineural deafness. We report the cases of two infants, aged 4 and 5 months,hospitalized for diabetic ketoacidosis requiring insulin therapy. Laboratorytests revealed megaloblasic anemia, thrombocytopenia and normal thiamine level.Neurosensorial investigations showed bilateral deafness and ophthalmicinvolvement. Treatment with oral thia ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,BRINI I,KHARFI M,MRAD K,BOUSSETTA K,BOUSNINA S,

Titre : Perianal presentation of Langerhans cell histiocytosis in children.

Référence : Gastroenterol Clin Biol. 2010 Jan;34(1):95-7. Epub 2009 Oct 27.

Résumé :

Langerhans cell histiocytosis, previously known as histiocytosis X, is a diseasewhose clinical presentation varies. Although it is uncommon, Langerhans cellhistiocytosis may involve the perianal region. We report the case of a 2-year-oldboy who presented with perianal ulcerated vegetative lesions and seborrheicdermatitis of the scalp. Biopsy of the lesions showed Langerhans cellhistiocytosis. This patient did not have any other organ involvement, which israre. The outcome was favourable with vin ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MRAD SM,GAZDALLI N,GHARSALLAH L,BOUYAHIA O,BARSAOUI S,BOUKTHIR S,SAMMOUD A,

Titre : [Study of 116 mothers of the knowledge, behavior, and practices of vitamin Dsupplementation]

Référence : Tunis Med. 2009 Apr;87(4):273-8.

Résumé :

BACKGROUND: In our country, the prevention of rickets is based on daily vitamin Dintake from birth to eighteen months. This vitamin D intake has decreasedaccording to our hospital practice. AIM: To assess vitamin D supplementationprevalence and to study mother knowledge, attitude and practices about vitamin Dand factors that influenced them and to define target population who needsfurther education. METHODS: A predefined questionnaire was submitted to 116mother's child who was aged from two mont ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MAZIGH SM,KAACH N,BOUYAHYA O,SAMMOUD A,

Titre : The effect of non-steroidal anti-inflammatory drugs and Helicobacter pyloriinfection on the gastric mucosa in children with upper gastrointestinal bleeding.

Référence : Pediatr Surg Int. 2010 Feb;26(2):227-30. Epub 2009 Oct 13.

Résumé :

OBJECTIVE: To study the effect of non-steroidal anti-inflammatory drugs (NSAID)and of Helicobacter pylori infection on the gastric mucosa in children with upperGI bleeding (UGIB). METHODS: Eighty-four children, 41 males (mean age 92.6months, 4-168 months) underwent an upper GI endoscopy with gastric biopsies forUGIB. Biopsies were analysed for histological assessment according to the updatedSydney classification and bacterial culture. The presence of H. pylori infectionwas retained when histolog ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : SABEUR H,CHEBIL BM,KARIM BA,SAMIR H,LEILA G,CHIRAZ H,SLAHEDDINE C,NEJI GM,

Titre : Langerhans cell histiocytosis revealed by painful hip: A case report.

Référence : Joint Bone Spine. 2009 Oct;76(5):565-6. Epub 2009 Sep 19.

Résumé :

Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to amultisystemic disease involving vital organs. Prognosis has been improved by useof chemotherapy. We report a 2-year-old girl with multifocal Langerhans cellhistiocytosis of bone and skin, revealed by a pain of the left hip and a limptrailing from 2 months. The diagnosis has been established by histological exam.The patient received chemotherapy and ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : TINSA F,BRINI I,EL MAY A,BOUSNINA D,BOUSSETTA K,BOUSNINA S,

Titre : Nodular regenerative hyperplasia of the liver,coeliac disease and Sjogren's syndrome in a child.

Référence : Gastroenterol Clin Biol. 2010 Jan;34(1):40-2. Epub 2009 Sep 17.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MRAD SM,KALACH N,SAMMOUD A,

Titre : Gastric atrophy and Helicobacter pyloriinfection in children.

Référence : Trop Gastroenterol. 2009 Apr-Jun;30(2):107-9.42: Banni M et al. Mixture toxicity assessment o...[PMID: 19758679] Related Articles, LinkOut

Résumé :

AIM: To assess the prevalence of gastric atrophy (GA) in Tunisia (a high prevalence region for Helicobacter pylori), and describe its histological,clinical and endoscopic features in children. METHODS: 345 children, 151 male and194 female, mean age 8.6 +/ - 3.7 years, underwent upper gastrointestinal (UGI)endoscopy with gastric biopsies for recurrent abdominal pain (n=232, 67.2%),vomiting (n=72, 20%) associated with or without upper gastrointestinal bleeding(n=59, 17.1%) and miscellaneous causes ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,GHARBI A,ESSID A,DRISS M,BOUSNINA S,

Titre : Giant condyloma acuminatum in an infant.

Référence : Pediatr Dermatol. 2009 Jul-Aug;26(4):488-9.

Résumé :

We report a 10-month-old boy who presented with a giant perianal condyloma acuminatum, and a similar lesion on the neck. These lesions were treated by surgical excision with satisfactory results. This size, extent, and early age of appearance make this case highly unusual. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,CHEBBI Y,MEDDEB M,BOUSNINA D,BOUSSETTA K,BOUSNINA S,

Titre : Monosomy 10q26-qter and trisomy 11q13-qter as a result of de novo unbalanced translocation.

Référence : J Appl Genet. 2009;50(3):289-91.

Résumé :

A male infant with partial monosomy 10 q and partial trisomy 11q as a result of de novo unbalanced translocation between the long arms of chromosomes 10 and 11: der(10)t(10;11)(q26;q13) is described. He had craniofacial dysmorphy, congenital heart defects, urogenital and cerebral anomalies, and severe developmental delay. To the best of our knowledge, this is the first report of this combination of chromosomal abnormalities. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIR S,TEBIB N,NASRALLAH F,BEN NOUR F,MIZOUNI H,ELASMI M,SANHAJI H,JEMAA R,FEKI M,BEN DRIDI MF,MEBAZAA A,KAABACHI N,

Titre : Phenylketonuria in Tunisian institutions for the mentally handicapped.

Référence : Arch Dis Child. 2009 Aug;94(8):647-8.

Résumé :

...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : pas d'institution définie

____________________________________________________________________________________


Auteurs : KHEMIRI M,LABASSI A JR,TLILI Y JR,BARSAOUI S,

Titre : Severe toxic methemoglobinemia mimicking septic shock in an infant.

Référence : Int Emerg Nurs. 2009 Jul;17(3):181-3. Epub 2009 Mar 18.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,CAILLAUD C,VANIER MT,BOUSNINA D,BOUSSETTA K,BOUSNINA S,

Titre : An Unusual Homozygous Arylsulfatase A Pseudodeficiency in a Metachromatic Leukodystrophy Tunisian Patient.

Référence : J Child Neurol. 2010 Jan;25(1):82-6. Epub 2009 Jul 2.

Résumé :

Metachromatic leukodystrophy is an autosomal recessive neurodegenerative lysosomal disease characterized by a deficiency of the lysosomal enzyme arylsulfatase A and the subsequent accumulation of sulfatide in neuronal and visceral tissues. Clinical diagnosis is usually confirmed by in vitro analysis of arylsulfatase A activity but may be complicated in cases of arylsulfatase A pseudodeficiency and sphingolipid activators protein deficiency. We report the case of a 3-year-old boy who presented a ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN BECHER S,CHEOUR M,ESSADDAM L,MATOUSSI N,FITOURI Z,

Titre : [Management of type 1 diabetes in childhood in Tunis: current report and perspectives]

Référence : Arch Pediatr. 2009 Jun;16(6):866-7.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN HARIZ M,

Titre : [Peptic ulcer in North Africa and Middle East]

Référence : Arch Pediatr. 2009 Jun;16(6):863-5.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : BEN TURKIA H,AZZOUZ H,TEBIB N,ABDELMOULA MS,BEN CHEHIDA A,MBAREK M,BEN HAMMOUDA M,BEN DRIDI MF,

Titre : [Tuberculosis and Brucellar spondylodiscitis co-infection]

Référence : Tunis Med. 2009 Mar;87(3):226-8.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : TINSA F,BEN RHOUMA A,GHAFFARI H,BOUSSETTA K,ZOUARI B,BRINI I,KARBOUL L,SOUID M,BOUSNINA S,

Titre : A randomized, controlled trial of nebulized terbutaline for the first acute bronchiolitis in infants less than 12-months-old.

Référence : Tunis Med. 2009 Mar;87(3):200-3.

Résumé :

BACKGROUND: Despite the common clinical practice, the available evidence on the efficacy of bronchodilators therapy for bronchiolitis is conflicting. The aim of this study is to evaluate the efficacy of nebulized terbutaline in bronchiolitis as measured by improvement in clinical score, oxygen saturation or reduction in duration of hospitalization. METHODS: This prospective, double blind, placebo controlled, randomized clinical trial was performed at Children's Hospital of Tunis from December 20 ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUYAHIA O,NCIBI N,FEDHILA F,AMDOUNI N,BEN AISSA J,MESSOUD T,BOUKTHIR S,SAMMOUD EL GHARBI A,

Titre : [Value of procalcitonin measurement in maternal fetal infection]

Référence : Tunis Med. 2009 Mar;87(3):191-5.

Résumé :

BACKGROUND: Materno foetal infection (MFI) remains one of the major causes of neonatal morbidity and mortality. Early detection of neonatal sepsis can be difficult, because the first signs of the disease may be unspecific and similar to symptoms of other non-infectious processes. AIM: We aimed to investigate the role of procalcitonin (PCT) in the diagnosis of fetal infection (MFI), and to compare it with those of the C-reactive protein (CRP). METHODS: We have conducted a prospective study during ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,BEN AMOR S,KAABACHI N,BEN LASOUAD M,BOUSSETTA K,BOUSNINA S,

Titre : Unusual case of thiamine responsive megaloblastic anemia.

Référence : Tunis Med. 2009 Feb;87(2):159-63.

Résumé :

BACKGROUND: Thiamine-responsive megaloblastic anemia syndrome is a rare autosomal recessive disorder defined by the occurrence of megaloblastic anemia, diabetes mellitus, and neurosensoriel deafness, responding in varying degrees to thiamine treatment. AIM: Report an unusual case of this rare disorder CASE REPORT: We report the case of a four-year-old boy who presented unusual features of thiamine-responsive megaloblastic anemia. In addition to the typical triad of the syndrome, he presented leu ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MAZIGH MRAD S,OUEDEMI M,BOUYAHIA O,GHARSALLAH L,BOUKTHIR S,GHARBI AS,

Titre : [Thrombocytopenic idiopathic purpura: predictive factors for chronic disease]

Référence : Tunis Med. 2009 Jan;87(1):72-5.

Résumé :

THE AIM of this study is to determine factors predicting development of chronic thrombocytopenic idiopathic purpura. METHODS: It was a retrospective study, regarding the cases of PTI diagnosed in 'service de medicine infantile C Hopital d'Enfants de Tunis' during 11 years. A comparison was done between two groups: the first including acute PTI and the second including chronic and recurrent PTI. Factors predicting development of chronic disease were searched by the Fisher test which was significa ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,LABESSI A,ZOUARI S,BORGI A,BEN MANSOUR F,OUBICH F,KHALDI F,BARSAOUI S,

Titre : [Tuberculosis in childhood: clinical features and problems in diagnosis. Report of 30 cases]

Référence : Tunis Med. 2009 Jan;87(1):61-7.

Résumé :

BACKGROUND: The clinical polymorphism and the low yield bacteriological tests make the diagnosis of tuberculosis (TBC) in children often difficult. THE AIM of this report is to specify hospital incidence of childhood TBC and to discuss problems in diagnosis. METHODS: We reviewed retrospectively cases of TBC enrolled at Medicine A Department in Children's Hospital of Tunis during the last ten years (1998-2007). Diagnosis of TB was supported according to bacteriological or histological confirmatio ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KAMEL M,BARKIA A,CHAABOUNI M,AOUADI R,SRAIRI R,ZOUARI B,AOUIDET A,

Titre : [Biologic profile in Tunisian infants (0-2 years), malnourished]

Référence : Tunis Med. 2009 Jan;87(1):22-7.

Résumé :

BACKGROUND: The malnutrition of the infants could be explained by a delay of the growth and the perturbation of biological parameters. AIM: To establish the nutritional profile of the Tunisian infant of less than two years. To specify the principal deficiencies and the possible origins of these deficiencies. METHODS: In our transverse exploratory study, carried out in period of 9 month. This study was conducted in two groups of Tunisian young children less than two years old: a control group and ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Ecole Supérieure des Sciences et Techniques de la Santé de Sfax

____________________________________________________________________________________


Auteurs : KAHLOUL N,MABROUK S,BOUGHAMOURA L,BOUGUEZZI R,AMRI F,

Titre : [Esophageal cervical duplication revealed by stridor: A case report.]

Référence : Arch Pediatr. 2009 Aug;16(8):1129-32.

Résumé :

Esophageal duplications are rare malformations. They account for 15 to 20% of esophageal malformations. Duplications are cystic or, rarely, tubular. The location is thoracic in 95% of the cases. The clinical manifestations are mostly related to compression of the neighboring organs. Treatment is surgical. We report a case of esophageal duplication in a 22-month-old child; the major symptom was congenital stridor. The diagnosis of esophageal duplication was suspected at the chest computed tomogra ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Régional de Kairouan Ibn El Jazzar

____________________________________________________________________________________


Auteurs : MRAD SM,BOUYAHIA O,FDHILA F,GHARSALLAH L,BOUKTHIR S,SAMMOUD A,

Titre : [Pulmonary haemosiderosis and celiac disease]

Référence : Tunis Med. 2008 Apr;86(4):403-4.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,KHALDI F,BEN BECHER S,CHAOUACHI B,HOUISSA T,BARSAOUI S,

Titre : Congenital lobar emphysema. Report of 17 cases.

Référence : Tunis Med. 2008 Apr;86(4):373-7.

Résumé :

The aim of this report is to determine frequency and clinical characteristics of Congenital lobar emphysema (CLE) at Children's Hospital of Tunis. METHODS: Cases of CLE managed between January the 1st 1994 until December the 31st 2004 were reviewed. RESULTS: Amongst 31 cases of cystic pulmonary malformations we report 17 CLE. They were 12 males and 5 females. The mean age at diagnosis was 41/2 months (20 days, 22 months). Symptoms were: progressive respiratory distress (n=11) recurrent attacks o ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MATOUSSI N,AMDOUNI N,FITOURI Z,MAKNI S,CHEOUR M,BEN BECHER S,

Titre : [Clinical and etiological features of primary adrenal insufficiencies in children]

Référence : Tunis Med. 2008 Oct;86(10):890-4.

Résumé :

BACKGROUND: The chronic primary adrenal insufficiency or Addison's disease is uncommon in children and belongs generally to a complex syndrome. AIM: Study of the clinical and aetiological features of primary adrenal insufficiencies in children. METHODS: In a retrospective study, we reviewed clinical and diagnostic data of all cases of Addison's disease admitted within a period of 15 years (from january 1991 to December 2006), in a department of paediatrics. Cases due to congenital adrenal hyperp ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,BRAHAM N,SELMI H,BOUGHATTAS S,ZBIDI A,ESSOUSSI AS,HARBI A,

Titre : [Graves's disease in children and adolescent: study of seven cases]

Référence : Tunis Med. 2008 Aug;86(8):728-34.

Résumé :

BACKGROUND: In spite of its rarity in the paediatric age, Graves' disease constitutes the principal aetiology of hyperthyroidism in child. AIM: Our goal is to analyze the clinical and evolutive particularities of Graves's disease in children. METHODS: We studied retrospectively seven cases of Graves' disease in children enrolled in the pediatrics department of Sousse during ten years period (1993-2002). RESULTS: There were six girls and one boy (sex - ratio = 0.16) aged 4.5 to 16 years (mean age ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUYAHIA O,BOUKTHIR S,MRAD SM,EL GHRABI AS,

Titre : [Diagnosis of hyper transaminasemia in childhood]

Référence : Tunis Med. 2008 Aug;86(8):722-7.

Résumé :

Elevated serum levels of transaminases must always be considered as an abnormal finding in children. Drugs and toxins must be eliminated first as possible hepatotoxic agents or co-factors. Antiviral hepatitis A immunoglobulin M serology is the first test to perform. However, others viruses with spontaneous benign courses are the most frequent cause. Only if initial presentation is severe or if liver tests remain abnormal after several weeks, other rare diseases can be sought. Aetiologies of pers ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN MANSOUR L,MAHFOUDH A,DJEMEL N,ALOULOU H,KAMMOUN T,KESKES H,GHORBEL M,HACHICHA M,

Titre : [Pulmonary invasive aspergillosis with thyroid and bony locations]

Référence : Tunis Med. 2008 Jul;86(7):720-2.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : KAMOUN T,DJEMAL N,ELLOUZ M,ALOULOU H,CHAABOUNI M,MAHFOUDH A,HACHICHA M,

Titre : [Hemolytic and uremic syndrome in children]

Référence : Tunis Med. 2008 Jul;86(7):715-7.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : CHEMLI J,ABID I,YACOUB M,GUEDIRA I,KORBI S,SAHLOUL ESSOUSSI A,HARBI A,

Titre : [Paediatric celiac disease in the region of Sousse: epidemiological and evolutive study of 80 cases]

Référence : Tunis Med. 2008 Jul;86(7):636-42.

Résumé :

AIM: Analyze epidemiological and evolutive profile of paediatric celiac disease in the region of Sousse. METHODS: We studied retrospectively 80 cases enrolled in the paediatrics' department of Sousse between 1993 and 2003. RESULTS: There were 44 girls and 36 boys (sex-ratio=0.81). The middle age of gluten introduction was 9 months, with extremes going from 1 to 24 months. Free interval between the introduction of gluten and the beginning of the symptoms was meaningfully more elevated in patients ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : CHEMLI J,MISSAOUI N,SELMI H,MILED H,DOGGI M,ESSOUSSI AS,HARBI A,

Titre : [Complete primary distal renal tubular acidosis in child about 11 cases]

Référence : Tunis Med. 2008 Jul;86(7):629-35.

Résumé :

AIM: Analyze the clinical and evolutive particularities of complete primary distal renal tubular acidosis in children, METHODS: We studied retrospectively 11 cases enrolled in the pediatrics department of Sousse during 10 years period (1993-2002). RESULTS: It is about 9 boys and 2 girls (sex-ratio = 45) aged 3 month to 5 years (mean age: 18 months). Diagnosis was suspected on clinical and biological data of presumption and confirmed by acidification test. Radiological investigation objectified a ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUYAHIA O,NAIJA O,MATOUSSI N,KHEMIRI M,BEN MANSOUR F,KHALDI F,

Titre : [Autoimmune hepatitis following acute hepatitis A: a care report]

Référence : Tunis Med. 2008 Jan;86(1):87-8.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,OUEDERNI M,BARSAOUI S,

Titre : Neonatal heart failure revealing a cardiac rhabdomyoma with tuberous sclerosis.

Référence : Tunis Med. 2008 Jan;86(1):75-7.

Résumé :

BACKGROUND: Cardiac rhabdomyoma is the most common cardiac tumour in childhood and is often associated to tuberous sclerosis (TS). However, a neonatal cardiac failure was uncommonly reported as the first manifestation of tuberous sclerosis. AIM: We report a case of a cardiac tumour revealed by a heart failure in a newborn who developed later clinical manifestations of TS. CASES REPORT: We report a case of a seven-day-old girl, admitted for cardiac failure. Echocardiography discovered a voluminou ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MELLOULI F,FEKIH J,BEN HAMED L,SFAR R,REZIGUA H,CHILLI H,BEJAOUI M,MOJAAT N,BOUKEF K,

Titre : [A cord blood bank in Tunisia: usefulness and feasibility]

Référence : Tunis Med. 2008 Jan;86(1):15-9.

Résumé :

BACKGROUND: The cord blood is a souce of hematopoietic stem cells. This haveencouraged the creation of many cord blood banks around the world. THE AIM: Bythis prospective study during 2 years, we tried to show the advantages of suchsources of progenitors ,and to evaluate our techniques of collection, freezing,biological and microbiological survey. METHODS: For this aim, we tested 100specimens of cord blood before and after defrosting. Our selection criteria werea volume > or = 60 ml, a CD 34+ ce ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : CHEMLI J,ABROUG M,KRIFA H,TLILI K,HARBI A,

Titre : [A rare cause of medullar compression in child: extensive spinal cord teratoma]

Référence : Tunis Med. 2008 May;86(5):524-5.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : MATOUSSI N,AISSA K,FITOURI Z,MAKNI S,BEN BECHER S,

Titre : [Autoimmune polyglandular syndrome type I]

Référence : Tunis Med. 2008 May;86(5):519-20.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BAHLOUL S,KAMOUN T,ELLOUZE MOHAMED ALOULOU H,ALOULOU H,MAHFOUDH A,HACHICHA M,

Titre : [Neonatal diabetes]

Référence : Tunis Med. 2008 May;86(5):515-7.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : CHEMLI J,HASSAYOUN S,KRID S,GHALI N,ABROUG S,ZAKHAMA A,HARBI A,

Titre : [Uremic and haemolytic syndrome in children: study of 17 cases]

Référence : Tunis Med. 2008 May;86(5):479-85.

Résumé :

BACKGROUND: In spite of its rarity, the haemolytic and uremic syndrome (HUS) constitutes the first aetiology of acute renal insufficiency (ARI) in child. AIM: The aim of this work is to analyze clinical and evolutive aspects of the HUS in child. METHOD: We studied retrospectively 17 cases of HUS in child enrolled in the paediatrics' department of Sahloul Hospital during eight years period (1996 to 2003). RESULTS: It is about four boys and 13 girls (sex-ratio = 0.3) aged three months to nine year ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : SFAIHI BEN MANSOUR L,THABET A,ALOULOU H,TURKI H,CHABCHOUB I,MHIRI F,MNIF Z,BEN ALI H,KAMMOUN T,HACHICHA M,

Titre : [Factor VII deficiency revealed by intracranial hemorrhage.]

Référence : Arch Pediatr. 2009 Jul;16(7):1024-7. Epub 2009 May 5.

Résumé :

Constitutional factor VII deficiency is a hereditary disease with recessive autosomic transmission. Its incidence is estimated to be 1/1,000,000 in the general population. We report a case of severe factor VII deficiency in infancy revealed by an intracranial hemorrhage in a 2-month-old infant. We describe the clinical, biological and therapeutic characteristics of this disease. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUYAHIA O,GHARSALLAH L,OUEDERNI M,BOUKTHIR S,MRAD SM,EL GHARBI AS,

Titre : Feminizing adrenocortical adenoma in a 5 year-old girl.

Référence : J Pediatr Endocrinol Metab. 2009 Jan;22(1):79-84.

Résumé :

Adrenocortical adenoma is a rare etiology of isosexual precocious puberty in girls. We report the case of a 5 year-old girl with isosexual precocious puberty. Abdominal ultrasound and magnetic resonance imaging revealed a well-defined mass of 32 x 28 mm situated in the left suprarenal region, but no signs of calcification or metastasis. Estradiol and testosterone levels were elevated, cortisol plasma level was normal, and bolus intravenous injection of GnRH showed unresponsiveness of LH and FSH. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUYAHIA O,BOUAFIF E,GHARSALLAH L,HAMZAOUI M,MEFTAH N,MRAD SM,BOUKTHIR S,EL GHARBI AS,

Titre : Foetus-in-fetu: an unusual cause of abdominal mass in the newborn.

Référence : Acta Chir Belg. 2009 Jan-Feb;109(1):130-2.

Résumé :

Foetus-in-fetu (FIF) is a rare congenital condition in which a vertebrate foetus is incorporated within its twin. The authors report the case of a newborn girl with prenatal ultrasonographic diagnosis of an intra-abdominal mass. Abdominal ultrasonography and computed tomography of the abdomen showed a heterogeneous cystic mass containing multiple calcifications. The patient had a laparotomy at 18 days of age with excision of a well-encapsulated 6 x 5 cm retroperitoneal mass, containing many orga ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KAHLOUL N,CHAARI W,BOUGHAMOURA L,CHARFEDDINE L,KHAMMERI S,AMRI F,

Titre : [Pseudohypoparathyroidism revealed by Fahr syndrome.]

Référence : Arch Pediatr. 2009 May;16(5):444-8. Epub 2009 Apr 1.

Résumé :

Fahr syndrome is defined by the presence of striopallidal notched bilateral and symmetric calcifications at the base of the skull. We report an observation of a 12-year-old girl who presented gait impairment, seizures, somnolence and aphasia. Brain computed tomodensitometry identified intracranial calcifications. The tests demonstrated pseudohypoparathyroidism. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Régional de Kairouan Ibn El Jazzar

____________________________________________________________________________________


Auteurs : GHRIBI A,JOUINI R,HELLAL Y,MAAZOUN K,NJIM L,KRICHENE I,MEKKI M,NOURI A,

Titre : Congenital Ureteral Valve Associated with Contralateral Renal Agenesis.

Référence : Eur J Pediatr Surg. 2009 Oct;19(5):339-40.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : MAZIGH MRAD S,BOUYAHIA O,TRABELSI M,GHARSALLAH L,BOUKTHIR S,SAMMOUD EL GHARBI A,

Titre : [Feminizing adrenocortical adenoma: a rare cause of isosexual precocious pubertyin girl]

Référence : Tunis Med. 2008 Jun;86(6):614-6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,ZAYANI M,BOU YAHYA O,ZOUARI S,BEN MANSOUR F,CAILLAUD C,KHALDI F,BARSAOUI S,

Titre : [Respiratory distress in infants with Pompe's disease]

Référence : Tunis Med. 2008 Jun;86(6):612-4.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,BEN RHOUMA A,BOUZID S,MESSAOUD T,GUESMI M,HAMZAOUI M,FATTOUM S,KHALDI F,BARSAOUI S,

Titre : [Clinical characteristics and outcome of cystic fibrosis: report of 16 cases]

Référence : Tunis Med. 2008 Jun;86(6):567-72.

Résumé :

AIM: The aim of this report is to determine clinical characteristics and outcome of Cystic Fibrosis (CF). METHODS: Cases of CF managed at Infantile Medicine A Department in Children's Hospital of Tunis during 13 years (1994-2006) were reviewed. RESULTS: 16 children had CF. They were 8 males and 8 females. 13 patients were consanguineous and four had similar familial cases. The mean age at diagnosis was 19 months (10 days, 13 years). 3/4 of patients were symptomatic within the first trimester of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,BEN RHOUMA A,KHARFI M,BORGI A,BEN MANSOUR F,ZOUARI S,BARSAOUI S,

Titre : [Anhydrotic ectodermal dysplasia: un uncommon cause of unexplained fever ininfants]

Référence : Tunis Med. 2008 Dec;86(12):1089-90.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,JALLOULI M,BEN LASSOUAD M,SMAOUI H,BRINI I,BOUSSETA K,BOUSNINA S,

Titre : Neonatal meningitis by Neisseria meningitidis B.

Référence : Tunis Med. 2008 Nov;86(11):1014-5.

Résumé :

BACKGROUND: Neisseria meningitidis is one of the major causes of meningitis in children and adolescents, but it is uncommonly found in neonatal meningitis. AIM: to report a rare case of meningitis by Neisseria meningitides B. CASE REPORT: We report the case of neonatal meningitis in a 20-day-old girl without shock or purpura. The symptoms were fever and seizures. The culture of cerebrospinal fluid showed to be positive for Neisseria meningitidis B. culture blood was negative. Antibiotic therapy ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,NECIB N,GUESMI M,BOUSNINA O,DOUIRA W,BOUSETTA K,BOUSNINA S,

Titre : Fanconi anemia complicated by neutropenic enterocolitis.

Référence : Tunis Med. 2008 Nov;86(11):1011-3.

Résumé :

BACKGROUND: Neutropenic enterocolitis (NEC) also known as typhlitis is an acute, life-threatening inflammation of the small and large bowel often seen in patients with leukaemia undergoing cytotoxic chemotherapy: occasionally this syndrome could present in other immunocompromised patients. AIM: To report an unusual case of Fanconi anemia complicated by neutropenic enterocolitis. CASE REPORT: We report a case of a 13-year-old boy affected by Fanconi anemia with severe neutropenia and who presente ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUYAHIA O,ESSADEM L,MATOUSSI N,GHARSALLAH L,FITOURI Z,MRAD MAZIGH S,BOUKTHIR S,BELLAGAH I,BEN BECHER S,SAMMOUD EL GHARBI A,

Titre : Etiology and outcome of bronchiectasis in children: a study of 41 patients.

Référence : Tunis Med. 2008 Nov;86(11):996-9.

Résumé :

BACKGROUND: Bronchiectasis remains an important cause of chronic suppurative lung disease in the developing world. The aim of this study is to describe the epidemiological characteristics, clinical features, underlying aetiologies and outcome of bronchiectasis in the paediatric hospital of Tunis. METHODS: A retrospective study of 41 children with bronchiectasis was conducted between January 1994 and December 2006. Diagnosis was made in patients with clinical suspicion of bronchiectasis associate ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,HARBI A,

Titre : [Treatment of steroid-resistant idiopathic nephrotic syndrome]

Référence : Arch Pediatr. 2009 Mar;16(3):260-8. Epub 2009 Feb 4.

Résumé :

Idiopathic nephrotic syndrome (INS) is the most frequent glomerular nephropathy in children. The response to corticoids distinguishes steroid-sensitive nephrotic syndrome (SSINS), by far the most frequent (90% of cases), from steroid-resistant nephrotic syndrome (SRINS). The steroid resistance of nephrotic syndrome is defined by the absence of remission after a full dose of oral corticosteroid therapy for 1 month followed by 3 pulses of intravenous methylprednisolone. Actually, INS constitutes a ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : TINSA F,AISSA K,MEDDEB M,BOUSNINA D,BOUSSETTA K,BOUSNINA S,

Titre : Multiple congenital anomalies/mental retardation syndrome with multiple circumferential skin creases: a new syndrome?

Référence : J Child Neurol. 2009 Feb;24(2):224-7.

Résumé :

We describe a combination of multiple congenital anomalies, a severe psychomotor retardation and seizures in a 9-year-old Tunisian boy with circumferential ringed skin creases. He had symmetrical circumferential skin creases on arms, legs, and penis. Craniofacial anomalies included: an elongated face, tight forehead, hypertelorism, bilateral epicanthic folds, upslanting palpebral fissures, microphthalmia, convergent strabismus, wide nasal bridge, aberrant teeth, dental caries, and low-set poster ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN TURKIA H,TEBIB N,KASDALLAH N,ABDELMOULA MS,AZZOUZ H,BEN CHEHIDA A,CAILLAUD C,BEN DRIDI MF,

Titre : [Neonatal cholestasis in an intermediate phenotype of type 2 Gaucher disease]

Référence : Arch Pediatr. 2009 Mar;16(3):255-7. Epub 2009 Jan 31.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BEN TURKIA H,TEBIB N,AZZOUZ H,ABDELMOULA MS,BEN CHEHIDA A,CAILLAUD C,BEN DRIDI MF,

Titre : Phenotypic continuum of type 2 Gaucher's disease: an intermediate phenotype between perinatal-lethal and classic type 2 Gaucher's disease.

Référence : J Perinatol. 2009 Feb;29(2):170-2.

Résumé :

The natural history and clinical presentation of the perinatal-lethal Gaucher's disease, a severe variant of acute type 2 Gaucher's disease, is quite different from classic type 2 Gaucher's disease. Rare reported patients had an overlapping phenotype between these two forms confirming that phenotyping may be difficult. Here we report three patients with an intermediate phenotype. The first two patients showed at birth cholestatic jaundice, hepatosplenomegaly and hematological involvement consist ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : MELLOULI F,OUEDERNI M,DHOUIB N,HAJKACEM MA,SLIM A,BEJAOUI M,

Titre : Successful treatment of influenza A virus by oseltamivir in bone marrow transplant recipients.

Référence : Pediatr Transplant. 2010 Mar;14(2):178-81. Epub 2008 Dec 19.

Résumé :

Mellouli F, Ouederni M, Dhouib N, Hajkacem MA, Slim A, Bejaoui M. Successful treatment of influenza A virus by oseltamivir in bone marrow transplant recipients. Pediatr Transplantation 2008. (c) 2008 Wiley Periodicals, Inc.Abstract: INFVA is an important cause of pulmonary infections in patients receiving BMT, and is associated with considerable morbidity and mortality for a readily preventable and treatable infection. Few studies have addressed the impact of the new neuraminidase inhibitors in ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : TINSA F,FARID O,DOUIRA W,RODRIGUEZ D,BURGLEN L,BOUSSETTA K,BOUSNINA S,

Titre : Megalencephalic leukoencephalopathy with subcortical cysts in a Tunisian boy.

Référence : J Child Neurol. 2009 Jan;24(1):87-9.

Résumé :

Megalencephalic leukoencephalopathy with subcortical cysts is an autosomal recessive cerebral white-matter disorder in children. Megalencephalic leukoencephalopathy with subcortical cysts is caused by mutation in the megalencephalic leukoencephalopathy with subcortical cysts gene 1. The authors report a case of a 2-year-old Tunisian boy who had presented seizure following minor head trauma. He had megalencephaly, cerebellar ataxia, and mild pyramidal signs at physical examination. Magnetic reson ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,LABASSI A JR,BAGAIS A JR,BARSAOUI S,

Titre : Toxic methemoglobinemia due to ibuprofen: Report of a pediatric case.

Référence : J Emerg Med. 2010 Aug;39(2):216-7. Epub 2009 Jan 25.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KRAOUA I,BENRHOUMA H,ROUISSI A,YOUSSEF-TURKI IB,ZOUARI B,KAABACHI N,GOUIDER-KHOUJA N,

Titre : [An overview of neurometabolic diseases in Tunisia. A 3-year prospective study.]

Référence : Rev Neurol (Paris). 2009 Jun-Jul;165(6-7):568-74. Epub 2009 Jan 24.

Résumé :

INTRODUCTION: Neurometabolic diseases are a large group of genetic diseases. In our country, the diagnostic and therapeutic approach to theses diseases is rather difficult. The aim of our study was to determine the frequency of neurometabolic diseases in the hospital population, to describe the problems in diagnosing these conditions and difficulties encountered during patient care. Our goal was to propose guidelines for a practical diagnostic and therapeutic approach to neurometabolic disorders ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Institut National de Neurologie Mongi Ben Hmida

____________________________________________________________________________________


Auteurs : MRAD SM,BOUKTHIR S,GHARSALLAH L,BOUYAHIA O,FATEN F,FETNI I,BARSAOUI S,ZOUARI B,SAMOUD A,

Titre : [Helicobacter pylori infection in childhood revealed by hematemesis: endoscopic and pathologic patterns]

Référence : Tunis Med. 2007 Nov;85(11):930-4.

Résumé :

BACKGROUND: Helicobacter pylori infection frequency in hematemesis was scarcely studied. AIM: to asses the frequency of this infection in children with upper gastrointestinal bleeding and to study the endoscopic and histological features. METHODS: It is a retrospective study including 180 children who underwent an endoscopy for upper gastrointestinal bleeding. Our population was divided in two groups. The group 1 (n=95) has performed gastric biopsy. The group 2 (n=95) has'nt performed gastric bi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MENIF K,KHALDI A,BOUZIRI A,KECHAOU W,BELHADJ S,HAMDI A,KAZDAGHLI K,BENJABALLAH N,

Titre : [Mortality rates in pediatric septic shock subordinate to community infection: About 70cases.]

Référence : Med Mal Infect. 2009 Dec;39(12):896-900. Epub 2008 Dec 24. Epub 2008 Dec 24.

Résumé :

GOAL: This study had for aim to determine the mortality rate and the factors affecting mortality among 70children admitted for septic shock secondary to a community acquired infection. PATIENTS AND METHODS: A retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU for septic shock secondary to a community-acquired infection. Neonates under 7days of age were excluded from the study. RESULTS: Seventy cases were included and 32 (45.7 %) of them ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TINSA F,JALLOULI M,DOUIRA W,BOUBAKER A,KCHIR N,HASSINE DB,BOUSSETTA K,BOUSNINA S,

Titre : Atypical teratoid/rhabdoid tumor of the spine in a 4-year-old girl.

Référence : J Child Neurol. 2008 Dec;23(12):1439-42.

Résumé :

Primary spinal atypical teratoid/rhabdoid tumor is extremely rare. The authors present a case of atypical teratoid/rhabdoid tumor occurring in a 4-year-old girl. Magnetic resonance imaging The authors showed an intramedullary mass extending from the bulbomedullary junction to T1 with leptomeningeal dissemination. The patient died 2 weeks after diagnosis. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : ZOUARI N,ABROUG S,BOUHLEL R,HASSAYOUN S,HMIDA RB,NABLI N,BOUSLAMA A,HARBI A,

Titre : [Cutaneous manifestations of primary hyperoxaluria]

Référence : Ann Dermatol Venereol. 2008 Nov;135(11):796-7. Epub 2008 May 23.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : CHABCHOUB I,BEN THABET A,MAALOUL I,ALOULOU H,KAMOUN T,DAOUED H,MNIF Z,HACHICHA M,

Titre : [A childhood case of antiphospholipid syndrome]

Référence : J Mal Vasc. 2009 Feb;34(1):61-4. Epub 2008 Dec 6.

Résumé :

Many conditions can lead to cerebral strokes in children. The antiphospholipid syndrome widely described in adults in association with systemic lupus erythematosus, is rare in childhood. CASE REPORT: Two months after recovering from varicella and a few days after an episode of bronchitis, a 17-month-old girl developed left facial paralysis associated with right hemiplegia. Brain MRI and angio-scan showed thrombosis in the internal left carotid associated with ischemia in the superficial posterio ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Habib Bourguiba

____________________________________________________________________________________


Auteurs : MELLOULI F,KSOURI H,DHOUIB N,TORJMEN L,ABDELKEFI A,LADEB S,OTHMAN TB,HMIDA S,HASSEN AB,BEJAOUI M,

Titre : Possible transfer of vitiligo by allogeneic bone marrow transplantation: A case report.

Référence : Pediatr Transplant. 2009 Dec;13(8):1058-61. Epub 2009 Nov 18.

Résumé :

Among the cases yet published of development of vitiligo after BMT, only two can claim as possible adoptive transfer of such disease. We report a case of a patient with sickle cell disease in whom vitiligo developed after allogeneic BMT from his HLA identical father affected by vitiligo. We reviewed and searched for some particularities in the reported cases of post-BMT vitiligo. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : BEN TURKIA H,TEBIB N,AZZOUZ H,ABDELMOULA MS,BEN CHEHIDA A,HUBERT P,DOUIRA W,BEN DRIDI MF,

Titre : [Congenital generalized lipodystrophy: a case report with neurological involvement]

Référence : Arch Pediatr. 2009 Jan;16(1):27-31. Epub 2008 Nov 20.

Résumé :

Congenital generalized lipodystrophy (CGL) is a rare disorder characterized by near complete absence of adipose tissue from birth. At least 2 genes located in 9q34 (AGPAT2) and 11q13 (Seipin) are implicated in type 1 and 2, respectively, and result in insulin resistance. We report here a novel case of CGL type 1 resulting from a novel homozygote mutation in the AGPAT2 gene. The clinical picture included pseudoathletic muscular hypertrophy, hypertrophic cardiomyopathy, enlarged liver, hypermetabo ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BEN TURKIA H,AMDOUNI N,AZZOUZ H,TEBIB N,ABDELMOULA MS,EL MAZNI F,HAMZAOUI A,BEN DRIDI MF,

Titre : [Atypical presentation of Wegener disease in childhood]

Référence : J Mal Vasc. 2008 Dec;33(4-5):242-6. Epub 2008 Nov 20.

Résumé :

The pediatric forms of Wegener granulomatosis (WG) are rare. The clinical picture and the profile have specificities compared to those of adults. We report a case of a girl aged of four years and a half who presented initially with a clinical picture of Henoch Schonlein purpura. Physical examination revealed additionally to purpura, scabby lesions on the buttocks. The histopathological examination of a skin biopsy disclosed histiocyte infiltration. There were no Ig A deposits on direct immunoflu ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : KHEMIRI M,HAMMAMI O,ZOUARI S,KHALDI F,BARSAOUI S,

Titre : [Plastic bronchitis: report of a pediatric case]

Référence : Rev Pneumol Clin. 2008 Oct;64(5):234-7. Epub 2008 Oct 26.

Résumé :

Plastic bronchitis (PB) is a rare disease, characterized by the formation of obstructive branching airways tracheobronchial casts. Commonly, PB often complicates the course of cardiac or respiratory disorders. The occurrence of PB before manifestation of the underlying respiratory disease is unusual. We report on the case of a boy, aged three years and eight months, free from underlying pulmonary disease, who presented with extensive atelectasis of the left lung during an acute respiratory tract ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : WAFA BR,AMEL B,SAMIR A,MOUNIR BS,NABIL BH,ZEINEB M,MOUNIR F,CHOKRI C,MAHFOUDH A,

Titre : [Adenocarcinoma of the rectum in a 14-year-old]

Référence : Arch Pediatr. 2008 Nov;15(11):1656-9. Epub 2008 Oct 9.

Résumé :

Colorectal cancer is rare in children and adolescents. It is usually associated with predisposing genetic factors, aggressive histology, and poor prognosis. Two familial syndromes are best characterized, hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis. They are autosomal dominant inherited disorders. We report the case of a 14-year-old girl having a Dukes D adenocarcinoma of the rectum with peritoneal extension and bone metastases. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : KHEMIRI M,LABBESSI A,TLILI Y,BEN MANSOUR F,BOUKTHIR S,BARSAOUI S,

Titre : [Digestive hemorrhage revealing a chronic esophageal foreign body. Report of apediatric case]

Référence : Arch Pediatr. 2008 Nov;15(11):1707-10. Epub 2008 Oct 1.

Résumé :

...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : pas d'institution définie

____________________________________________________________________________________


Auteurs : KHEMIRI M,OUEDERNI M,BEN MANSOUR F,BARSAOUI S,

Titre : Bronchogenic cyst: an uncommon cause of congenital lobar emphysema.

Référence : Respir Med. 2008 Nov;102(11):1663-6. Epub 2008 Aug 28.

Résumé :

We report a case of a 1-month-old boy who has developed respiratory distress. Chest X-ray and CT scan showed over distension of the left upper lobe and a mediastinal shift in favour of congenital lobar emphysema (CLE) of the left upper lobe. One month after uneventful lobectomy, he was readmitted at hospital for another episode of respiratory distress. Chest radiography revealed relapse of compressive emphysema in the remaining left lobe. Gastro oesophageal transit and MRI were performed, which ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEHIDA AB,TEBIB N,CHERIF W,TURKIA HB,ABDELMOULA S,AZZOUZ H,BEN DRIDI MF,

Titre : Glycogen storage disease type I in Tunisia: An epidemiological analysis.

Référence : J Inherit Metab Dis. 2008 Dec;31 Suppl 2:S199-204. Epub 2008 Aug 5.

Résumé :

Objective: Analysis of epidemiological data concerning GSD I in Tunisia. Subjects and methods: All the cases diagnosed as GSD I between 1992 and 2005 in a paediatric department recruiting all the metabolic diseases referred from the North of Tunisia were reviewed. Individual data (sex, socioeconomic and educational background, geographic origins, insurance coverage) were collected and pedigrees were reconstituted. Results: Twenty-two cases (9 boys and 13 girls from 20 homes) were identified. Fou ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BOUYAHIA O,NESSERINE N,GHARSALLAH L,MAZIGH SM,DAGHFOUS R,BOUKTHIR S,EL GHARBI AS,

Titre : A case of anaphylactic reaction to ibuprofen in a child with Still's disease.

Référence : Therapie. 2008 Mar-Apr;63(2):155-6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : GHRIBI A,MEKKI M,KRICHENE I,JOUINI R,MAAZOUN K,SAHNOUN L,BRAHIM MB,BELGHITH M,HAFSA C,ZAKHAMA A,NOURI A,

Titre : Congenital bilobar emphysema.

Référence : J Pediatr Surg. 2008 Aug;43(8):e5-7.

Résumé :

Congenital bilobar emphysema is reported to be extremely rare. We describe 3 cases, and we review the diagnosis problems and treatment methods of this childhood respiratory tract pathologic condition. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : TURKIA HB,TEBIB N,AZZOUZ H,ABDELMOULA MS,BOUGUILA J,SANHAJI H,MILADI N,MAIRE I,CAILLAUD C,KAABACHI N,BEN DRIDI MF,

Titre : Phenotypic spectrum of fucosidosis in Tunisia.

Référence : J Inherit Metab Dis. 2008 Dec;31 Suppl 2:S313-6. Epub 2008 Jul 27.

Résumé :

Fucosidosis (OMIM 230000) is a rare autosomal recessive lysosomal disorder due to deficient alpha-L: -fucosidase activity(EC 3.2.1.51), leading to the accumulation of fucose-containing glycolipids and glycoproteins in various tissues. This study contained the largest ever Tunisian survey of fucosidosis patients, diagnosed during the period 1987-2007. The clinical pictures and outcomes of these patients are compared with literature data. Ten patients (8 boys and 2 girls) from six unrelated famili ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : KHEMIRI M,OUEDERNI M,KHALDI F,BARSAOUI S,

Titre : Screening for celiac disease in idiopathic pulmonary hemosiderosis.

Référence : Gastroenterol Clin Biol. 2008 Aug-Sep;32(8-9):745-8. Epub 2008 Jul 7.

Résumé :

AIM: The aim of this report was to screen for celiac disease (CD) in patients with idiopathic pulmonary hemosiderosis (IPH). PATIENTS AND METHODS: Patients with IPH treated at the Children's Hospital of Tunis between 1976 and 2006 were reviewed and investigated for CD, using serological and histological tests. RESULTS: A total of 10 children (two boys and eight girls) had IPH. The mean age at diagnosis was 3.1 years. Three had digestive symptoms and positive CD serology, which was confirmed by h ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,OUEDERNI M,BEN MANSOUR F,BEN JABALLAH N,BARSAOUI S,

Titre : [Acute respiratory failure revealing an idiopathic acute eosinophilic pneumonia: report of a pediatric case]

Référence : Ann Fr Anesth Reanim. 2008 Jun;27(6):502-4. Epub 2008 Jun 18.

Résumé :

Eosinophilic pneumonias are a group of heterogeneous disorders, rarely reported in children. We describe a case of a 12-year-old boy hospitalized for an acute febrile respiratory failure. Chest radiograph showed bilateral diffuse infiltrates. A pulmonary eosinophilic infiltration was confirmed by a major blood eosinophilia at 33,800/mm(3) associated with increased eosinophilic rate (90%) on bronchoalveolar lavage fluid. Outcome improved markedly with mechanical ventilation and corticosteroid the ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : SFAIHI BEN MANSOUR L,AYEDI A,CHAARI W,ALOULOU H,KAMMOUN T,MNIF Z,MAHFOUDH A,TRIKI C,HACHICHA M,

Titre : [Moyamoya and Down syndrome: about 2 cases]

Référence : Arch Pediatr. 2008 Jul;15(7):1197-200. Epub 2008 May 27.

Résumé :

Moyamoya syndrome has rarely been reported in association with Down syndrome. We report on 2 cases in 3-year-old and 6-year-old female children with Down syndrome, who presented with neurological deficit. Imaging (magnetic-resonance angiography and digital-subtraction angiography) revealed the classical Moyamoya pattern. The neurological deficits persisted in both cases. One patient has developed epilepsy. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : MATOUSSI N,AISSA K,FITOURI Z,HAJJI M,MAKNI S,BELLAGHA I,BEN BECHER S,

Titre : [Central diabetes insipidus: diagnostic difficulties]

Référence : Ann Endocrinol (Paris). 2008 Jun;69(3):231-9. Epub 2008 May 19.

Résumé :

Central diabetes insipidus is rare in children. Characteristic features include polyuria and polydipsia due to arginine vasopressin deficiency. The differential diagnosis of polyuric states may be difficult. Etiologic diagnosis of central diabetes insipidus may be an equally difficult task. OBJECTIVE: To specify the difficulties encountered in the diagnosis of central diabetes insipidus and to point out features of the etiologic work-up and of long-term follow-up of children with idiopathic cent ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TAHAR GT,NEJIB KN,SADOK SS,RACHID LM,

Titre : Adrenocortical oncocytoma: a case report and review of literature.

Référence : J Pediatr Surg. 2008 May;43(5):E1-3.

Résumé :

Oncocytic tumors of the adrenal gland are uncommon. Most of these oncocytomas are benign and nonfunctioning. We report the case of functioning adrenocortical located in the right adrenal gland in a 6-year-old girl who presented with pseudoprecocious puberty and elevation of the estradiol level. She had an adrenalectomy. The tumor was small and composed predominantly of oncocytes. No criteria of malignancy were found. A discussion of this case and a review of the literature on this entity are pre ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Charles Nicolle

____________________________________________________________________________________


Auteurs : JALEL C,ABDELAZIZ H,KALTHOUM T,ZOUHEIR T,

Titre : [Central precocious puberty and hypothalamic hamartoma].

Référence : Tunis Med. 2008 Feb;86(2):187-8.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BEN HARIZ M,BEN MRAD S,HALIOUI S,RZGUI L,MILADI N,TEBIB N,SETA N,MAHERZI A,

Titre : [Hepatomegaly and early cytolysis as presenting symptoms in CDG syndrome type Ia]

Référence : Tunis Med. 2008 Feb;86(2):204-7.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : BOUYAHIA O,KHELIFI I,MAZIGH SM,GHARSALLAH L,CHAOUACHI B,HAMZAOUI M,BARSAOUI S,BEN BECHER S,BOUSNINA S,BOUKTHIR S,EL GHARBI AS,

Titre : [Cholestasis in infants: a study of the Children's Hospital of Tunisia]

Référence : Tunis Med. 2008 Feb;86(2):128-35.

Résumé :

BACKGROUND: Cholestasis in infant constitutes an heterogeneous group of disease; diagnosis and management are often difficult. THE AIM of the study is to describe clinical, paraclinical characteristics and outcome of infants hospitalized for cholestasis in children's Hospital of Tunis. METHODS: A retrospective study of 94 infants with cholestasis was conducted. Patients were hospitalized in four departments of paediatrics of our hospital between January 1995 and December 2005. Cholestasis compli ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : ALOULOU H,CHAARI W,KHANFIR S,ZROUD N,KAMMOUN TH,ABDELMOULA M,HACHICHA M,

Titre : [Aplasia cutis congenita of the scalp (5 observations)]

Référence : Arch Pediatr. 2008 Apr;15(4):382-7. Epub 2008 Mar 10.

Résumé :

Aplasia cutis congenita (ACC) is an uncommon congenital malformation. It is characterized by defects of the skin that occur most frequently on the scalp along the midline, but can also be localized on the trunk, face and limbs, usually with a symmetrical distribution. When it is localized in the skull, it can extend to the dura mater, with only the thin pia mater to protect the brain. PATIENTS AND METHODS: We report a retrospective study during a period of 10 years and we report 5 cases of ACCV ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUKTHIR S,AOUIDIDI F,MAZIGH MRAD S,FETNI I,BOUYAHYA O,GHARSALLAH L,SAMMOUD A,

Titre : [Chronic gastritis in children]

Référence : Tunis Med. 2007 Sep;85(9):756-60.

Résumé :

BACKGROUND: Active gastritis, atrophic gastritis (AG) and intestinal metaplasia are lesions associated with Helicobacter pylori (H. pylori) infection in adults. AIM: To assess the prevalence of chronic gastritis, its histological characteristics and clinical features in children. METHODS: 345 children (M/F: 151/194, mean age: 8.6 +/- 3.7 years; range: 1-18 years) were enrolled, referred for upper gastrointestinal endoscopy (UGI endo) with clinical manifestations of gastritis, i.e., recurrent abd ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHAABOUNI M,BAHLOUL S,BEN ROMDHANE W,BEN SALEH M,BEN HALIMA N,CHOUCHENE C,BEN HMAD A,ZROUD N,KAMMOUN T,KARRAY A,

Titre : [Epidemiological, etiological and evolutionary aspects of children cirrhosis in adeveloping country: experience of the pediatric department of SFAX Universityhospital, Tunisia].

Référence : Tunis Med. 2007 Sep;85(9):738-43.

Résumé :

BACKGROUND: Cirrhosis is rare in pediatrics. The children cirrhosis is particularby the ascendancy of biliairy cirrhosis and cirrhosis due to an innate error ofmetabolism and by the relative frequency of the cases where an etiologicaltreatment is possible. However in developing countries, the children cirrhosisstill put problems of etiological diagnosis and of therapeutic coverage. AIM: Tostudy epidemiological and etiological particularities, therapeutic modalities andoutcome of cirrhosis in the ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : KHEMIRI M,BARSAOUI S,

Titre : [Infancy asthma: diagnostic and therapeutic approach]

Référence : Tunis Med. 2007 Sep;85(9):715-21.

Résumé :

BACKGROUND: Asthma in infants is characterized by recurrence of three episodes of dyspnea and wheezing within two first years of age. Asthma in infancy is a heterogeneous condition with different clinical phenotypes and outcome. So, the diagnostic and therapeutic approach are often difficult. THE AIM of this systematic review was to provide answers to the following questions in the management of recurrent wheeze in infants: is it asthma?, should we treat wheezy infants?, what are the modalities ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,KRID S,BOUSSETTA S,ABROUG S,BEN DHIA N,GHEDIRA I,SFAR MT,ESSOUSSI AS,HARBI A,

Titre : [Lupus nephritis in childhood: clinical and evolutive study of 14 cases]

Référence : Tunis Med. 2007 Aug;85(8):644-50.

Résumé :

BACKGROUND: Renal involvement is one of the most severe and frequent manifestations of the systemic lupus erythematosus (SLE). Aim : In this study, we analyzed clinical and evolutive particularities of 14 paediatric cases of lupus nephritis (LN). METHODS: It's a retrospective study in 14 children with lupus nephritis followed-up in the paediatrics department of Sousse and Mahdia between 1983 and 2004. RESULTS: There were 12 girls and two boys (sex-ratio = 0.16) aged four to 14 years (mean age =1 ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUZIRI A,BEN SLIMA S,HAMDI A,MENIF K,BELHADJ S,KHALDI A,KECHAOU W,KAZDAGHLI K,BEN JABALLAH N,

Titre : [Acute respiratory distress syndrome in infants at term and near term about 23 cases]

Référence : Tunis Med. 2007 Oct;85(10):874-9.

Résumé :

AIM: to precise the incidence of acute respiratory distress syndrome in infants at term and near term and the clinical characteristics of this disease not yet well recognised. METHODS: Retrospective study of the medical records of infants admitted in the paediatric intensive care unit for ARDS along a period of 4 years. Diagnosis of ARDS was based on the following criterias: (1) Gestational age > or =35 weeks of gestation; (2) Severe and immediate respiratory distress requiring mechanical ventil ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MATOUSSI N,FITOURI Z,MAAROUFI N,BERRICHE I,BEN BECHIR S,

Titre : [Epidemiologic profile and management pediatric medical emergencie's consultants of Tunisian child's hospital]

Référence : Tunis Med. 2007 Oct;85(10):843-8.

Résumé :

BACKGROUND: the pediatric medical emergencie's of Tunisian child's hospital service manages all children fifteen years old. It receives 45,000 children in year in average. THE AIMS: Establish an epidemiologic profile of consultants and study the encountred morbidity. METHODS: We made a transversal describing study of the pediatric emergencie's activity during three successive months in 2004 (February, March, April). We described the characteristics of the population consulting this service, stud ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HAMMAMI O,BEN SALEM K,BOUJEMAA Z,CHEBBI Y,AOUN S,MEDDEB I,ABID F,GANDOURA N,

Titre : [Epidemiologic and clinical features of congenital heart diseases in children at the Bizerta Hospital]

Référence : Tunis Med. 2007 Oct;85(10):829-33.

Résumé :

The aim of this study is to establish the epidemiologic profile of congenital heart disease in newborns in a Tunisian department of the north west of Tunisia. METHODS: We report 79 cases of congenital heart defects treated which are followed up in the department of general paediatrics in the University Hospital of Bizerta during 9 years. The informations concerning the patients is taking to a data file. The newborns included had a congenital heart disease suspected clinicly or confirmed by a car ...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Bizerte Habib Bougatfa

____________________________________________________________________________________


Auteurs : MELLOULI F,KSOURI H,TORJMEN L,ABDELKEFI A,LADEB S,BEN OTHMAN T,BEN HASSEN A,BEJAOUI M,

Titre : Transmission of type 1 diabetes by bone marrow transplantation: a case report.

Référence : Pediatr Transplant. 2009 Feb;13(1):119-22. Epub 2008 Jan 16.

Résumé :

T1D after BMT constitutes a human model of autoimmune disease transmission. This case report refers to T1D onset after allogeneic HLA-matched BMT in a six-yr-old recipient affected by aplastic anemia. The donor was his sister who had T1D. The recipient had a complication free course apart from grade 1 acute GVHD, which was resolved spontaneously. With the predictive value and significance of T1D-associated autoantibodies, we tried to consolidate the T1D transfer possibility based on our patient ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : DJEMAL N,BEN AMMAR H,MASMOUDI K,RGUAIEG R,TRIGUI L,BEN HMAD A,KANNOU M,HMIDA N,GARGOURI A,ZOUARI N,REKIK A,

Titre : [Pulmonary function in children after neonatal meconium aspiration syndrome]

Référence : Arch Pediatr. 2008 Feb;15(2):105-10. Epub 2008 Jan 18.

Résumé :

BACKGROUND: Meconium aspiration syndrome is a disease of the newborn mature or post mature. The acute pulmonary consequences can be extremely severe. In the few studies of the long-term pulmonary sequelae, it seems that certain children surviving meconium aspiration syndrome keep an obstructive syndrome. The aim of our study was to assess long term respiratory residual damage from meconium aspiration syndrome. METHODS: During a seven-year period going from 1994 to 2000, we reviewed the files of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : MELLOULI F,BEJAOUI M,

Titre : [The use of hydroxyurea in severe forms of sickle cell disease: study of 47 Tunisian paediatric cases]

Référence : Arch Pediatr. 2008 Jan;15(1):24-8. Epub 2007 Dec 31.

Résumé :

INTRODUCTION: The Sickle Cell Disease (SCD) is a serious illness considering its complications. For the children seriously affected, three therapeutic options are currently validated: transfusion therapy, hydroxyurea and bone-marrow transplantation. OBJECTIVES: To see the contribution of hydroxyurea therapy on severe forms of SCD in affected Tunisian children. MATERIAL AND METHODS: This investigative study lasted over 6 years and 9 months, (September 2000-May 2007), enrolling 47 patients includi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : MATOUSSI N,AMEUR HB,AMOR SB,FITOURI Z,BECHER SB,

Titre : [Cardiotoxicity of n-methyl-glucamine antimoniate (Glucantime). A case report]

Référence : Med Mal Infect. 2007 Dec;37 Suppl 3:S257-9. Epub 2007 Nov 28.

Résumé :

The pentavalent antimonial meglumine (Glucantime) is the drug of choice in treatment of cutaneous leishmaniasis in Tunisia. It may create severe adverse effects. A ten year-old girl was treated by Glucantime for cutaneous leishmaniasis. On the eighth day of treatment, she developed palpitations and precordialgia. The ECG showed T wave inversion prolongation of corrected QT interval. Drug therapy was stopped. Within a few days, she recovered and her elctrocardiographic changes came back to normal ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : FITOURI Z,BEN SLIMA S,MATOUSSI N,ALOUI N,BELLAGHA I,KECHRID A,BEN BECHER S,

Titre : [Currarino syndrome a rare cause of recurrent purulent meningitis]

Référence : Med Mal Infect. 2007 Dec;37 Suppl 3:S264-7. Epub 2007 Nov 26.

Résumé :

The authors report a case of partial Currarino syndrome in a three and a half year old child with a left hemisacrum agenesis and a presacral mature teratoma. The special aspect of the observation was the apparition of repetitive polymicrobial purulent meningitis (Escherichia coli, Streptococcus B, Haemophilus influenzae) treated several times with non-specific antibiotics without normalization of CSF, particularly the CSF glucose, which remained low, justifying the use of an antimycobacterial tr ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BARKAOUI E,CHERIF W,TEBIB N,CHARFEDDINE C,BEN RHOUMA F,AZZOUZ H,BEN CHEHIDA A,MONASTIRI K,CHEMLI J,AMRI F,BEN TURKIA H,ABDELMOULA MS,KAABACHI N,ABDELHAK S,BEN DRIDI MF,

Titre : Mutation spectrum of glycogen storage disease type Ia in Tunisia: implication for molecular diagnosis.

Référence : J Inherit Metab Dis. 2007 Nov;30(6):989. Epub 2007 Nov 19.

Résumé :

Glycogen storage disease type Ia (GSD Ia; OMIM 232200) is an autosomal recessive disorder of glycogen metabolism caused by a deficiency of the microsomal glucose-6-phosphatase (G6Pase). It is characterized by short stature, hepatomegaly, hypoglycaemia, hyperuricaemia, and lactic acidaemia. Various mutations have been reported in the G6Pase gene (G6PC). In order to determine the mutation spectrum in Tunisia, we performed mutation analysis in 22 Tunisian type I glycogen storage disease (GSD I) pat ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BEN JABALLAH N,BOUZIRI A,MNIF K,HAMDI A,KHALDI A,KCHAOU W,

Titre : Epidemiology of hospital-acquired bloodstream infections in a Tunisian pediatric intensive care unit: a 2-year prospective study.

Référence : Am J Infect Control. 2007 Nov;35(9):613-8.

Résumé :

BACKGROUND: There are few data providing rates of nosocomial bloodstream infections (NBI) in pediatric intensive care patients from developing regions of the world. OBJECTIVES: To describe the epidemiology of NBI in a Tunisian pediatric intensive care unit (PICU). METHODS: A prospective surveillance study from January 2004 through December 2005 was performed in the PICU of the Children's Hospital of Tunis. All patients who remained in the PICU for more than 48 hours were included. Centers for Di ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MELLOULI F,TORJMEN L,KSOURI H,ABDELKEFI A,LADAB S,BARBOUCHE R,OTHMAN TB,HASSEN AB,BEJAOUI M,

Titre : Bone marrow transplantation without conditioning regimen in Omenn syndrome: a case report.

Référence : Pediatr Transplant. 2007 Dec;11(8):922-6.

Résumé :

OS is a non-SCID immunodeficiency characterized by a poor outcome even after BMT. We report here a case of BMT without preparative conditioning regimen, and with a successful engraftment in a five-month-old infant with OS. The patient was transplanted with 15 x 10(8) bone marrow mononuclear cells/kg, from his HLA matched brother, without preparative regimen and GVHD prophylaxis. Immunological status was assessed before and after the BMT, and the engraftment was monitored with microchimerism anal ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : DJEMAL N,BEN SALAH M,BEN HLIMA N,BEN RHOMDHANE W,BEN AMMAR H,CHAABOUNI M,CHOUCHANE C,KARRAY A,

Titre : [Devic's neuromyelitis optica in children: a case report and review of the literature]

Référence : Arch Pediatr. 2007 Nov;14(11):1337-40. Epub 2007 Oct 17.

Résumé :

Devic neuromyelitis optica (NMO) or Devic's syndrome is an uncommon clinical syndrome associating unilateral or bilateral optic neuritis and transverse myelitis. Usually reported in adults, childhood cases constitute a distinctive clinical entity. CASE REPORT: We report a case of NMO occurring in a 9-year-old girl, admitted for paraplegia, sphincter troubles as acute installation bladder retention and of a sudden decline of the visual acuity. Magnetic resonance imaging (MRI) revealed abnormaliti ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : ABDELMOULA MS,ABDELMALEK R,CHLEYFA K,BEJAOUI M,TEBIB N,BEN TURKIA H,BEN DRIDI MF,

Titre : [Pulmonary aspergillosis in a child with chronic granulomatous disease]

Référence : Tunis Med. 2003 Oct;81(10):815-20.

Résumé :

The chronic granulomatous disease is characterised by the occurence of multiplebacterial and fungal infections since the early childhood. This susceptibility toinfections must be prevented by a primary prophlylaxis against the opportunisticgerms like pneumocystis and aspergillus. Our case is about a twelve-year-old boywho had a prophylaxis since his fourth month of life. At 10 years he presented apleuro-pneumonia refractory to a large spectrum antibiotherapy. The aspergillaretiology was establis ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : BEN HALIMA N,KRICHEN A,MEKKI MA,BEN ML,CHABCHOUB I,CHAABOUNI M,TRIKI A,KARRAY A,

Titre : [Persistent forms of cow's milk allergy. Report of 6 cases]

Référence : Tunis Med. 2003 Sep;81(9):731-7.

Résumé :

BACKGROUND: Cow's milk allergy is defined as reproducible adverse reaction to a food protein antigen which is immune medieted. About 80 to 90 % become clinically tolerated within the first three year of live. The aim of this study is to evaluate the clinical, immunological and evolutive characteristics of the 10 % to 20 % of persistent form of cow's milk allergy. METHODS: This study included six persistent form of cow's milk allergy (2 boys and 4 girls). The provocation challenge test according ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : KHALDI F,BAHRI R,ZOUARI S,

Titre : [Acute severe asthma in infants. Study of 34 cases]

Référence : Tunis Med. 2003 Sep;81(9):715-20.

Résumé :

Acute severe asthma is the most severe acute complication of infant asthma. The aim of our study was to specify its characteristics in the Tunisian infant and analysis his initial medical care. It is a retrospective study included 34 infants less than 3 year old, admitted during the period from January 1, 1995 to December 31, 2000. The acute severe asthma was induced by a respiratory viral infection in 80 % of cases. The delay hospitalisation was upper than 48 hours in 56 % of the cases. Before ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : GHEDIRA-BESBES L,MALLEK A,GUEDICHE MN,

Titre : [Idiopathic nephrotic syndrome in children: report of 57 cases]

Référence : Tunis Med. 2003 Sep;81(9):702-8.

Résumé :

The aim of this study was to analysis epidemiological, clinical, biochemical and histopathological profile of INS in children and to document their management and their final course. A retrospective study of 57 children with INS hospitalized in the pediatric department of Monastir hospital from the 1st of January 1989 to the 31 th of December 1999 was conducted. The annual rate was of 3,2 cases 1000 admissions, sex ratio was of 1,28 with 32 boys and 25 girls. The mean age at the onset of the aff ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : MRAD SM,BOUKHTHIR S,OUBICH F,GHARSALLAH L,BARSAOUI S,

Titre : [Treatment of upper gastrointestinal bleeding in portal hypertension in children]

Référence : Tunis Med. 2007 Mar;85(3):184-8.

Résumé :

Variceal bleeding is the most common cause of severe gastrointestinal bleeding in chilhood. Biliary atresia and portal venous obstruction are the most common causes. The patients with acute bleeding, pharmacotherapy with octreotide should be used immediately. All of these patients should undergo therapeutic endoscopy with band ligation. All children surviving variceal hemorrage should undergo secondary prophylaxis with band ligation. Transjugular intrahepatic portosystemic shunt creation in chil ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KAMMOUN T,BEN ABDALLAH R,CHABCHOUB I,BAHLOUL S,ALOULOU H,MAHFOUDH A,HACHICHA M,

Titre : [Hepatopulmonary syndrome and portal hypertension]

Référence : Tunis Med. 2007 Feb;85(2):170-3.

Résumé :

BACKGROUND: The hepatopulmonary syndrome is known by the association of chronic hepatopathy and refractory hypoxemia linked to pulmonary vasodilatation. The hepatopathy may be an hepatic cirrhosis, a congenital porto-case shunt, a porte cavernous angioma or a portal high blood pressure. AIM: Report new cases CASE REPORT: We report the observation of a girl followed from the age of 5 years for type I auto-immune hepatitis complicated of portal high blood pressure, in whom the hepatopulmonary synd ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN HARIZ M,BEN FARHAT L,HLIOUI S,CHOUROU O,ESSAFI-KALLEL K,MAHJOUB A,CHAKER E,BEN AMMAR B,MAHERZI A,

Titre : [Imported Schistosoma haematobium infection: report of 9 cases]

Référence : Tunis Med. 2007 Feb;85(2):150-4.

Résumé :

BACKGROUND: Schistosomia haematobium infection has been eradicated from Tunisia since 1980. Only some imported cases are noted each year. AIM: The authors report nine cases of Schistosomia haematobium infection diagnosed. METHODS: The diagnosis was carried out within the framework of a survey carried out by the service of Pediatry of the hospital Mongi Slim of Tunis concerning 20 students of African extraction. RESULTS: Hematuria was found in all cases. Schistosomia haematobium infection is diag ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : BOUKTHIR S,SLIMI A,MAZIGH S,OUBICH F,DEBBABI A,BARSAOUI S,

Titre : [Chronic constipation in childhood. A report of 78 patients]

Référence : Tunis Med. 2007 Feb;85(2):109-15.

Résumé :

AIM: To assess the aetiology and the clinical patterns of chronic constipation in children. METHODS: A total of 78 patients (62% boys, mean age: 4.6 years) were enrolled in this retrospective study. For each patient, we collected these data: clinical features, radiological data, rectal manometry and rectal biopsy results, treatment and follow up. RESULTS: Functional constipation was the most frequent cause of chronic constipation (49 cases, 62.8%) followed by Hirschsprung's disease (19 cases, 24 ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HACHICHA M,KAMMOUN T,BEN ROMDHANE W,BEN ABDALLAH R,MAHFOUDH A,KAMMOUN K,HACHICHA J,TRIKI A,

Titre : [Vasculitis with renal involvement and antineutrophil cytoplasmic antibodies (ANCA) in a child receiving benzylthiouracil]

Référence : Nephrol Ther. 2007 Jul;3(4):147-51. Epub 2007 May 23.

Résumé :

Vasculitis associated to antineutrophil cytoplasmic antibodies (ANCA) is a rare complication of therapy with antithyroid medication. They were mainly described in patients treated with propylthiouracil (PTU), carbimazole, methimazole and rarely by benzylthiouracil (Basden). We report a case of 12-years-old girl treated by benzylthiouracil for Grave's disease who developed after 2 years vasculitis associated with cutaneous involvement (generalized ulcer necrotic purpura) and glomerulonephritis wi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : HALIOUI-LOUHAICHI S,BEN M'BAREK S,BEN HARIZ M,BEN FARHAT L,BRIKI S,HENDAOUI L,MORNET E,MAHERZI A,

Titre : [A novel mutation in infant hypophophatasia: a case report]

Référence : Tunis Med. 2007 May;85(5):433-6.

Résumé :

BACKGROUND: Hypophosphatasia is a rare inherited disorder characterized by defective bone and teeth mineralization and deficiency of serum and bone alkaline phosphatase activity. Several mutations in the TNSALP gene are identified. AIM: The authors describe a Tunisian case having a mutation that has not been described up to now. CASE: It is about an infant, in the antecedents of recurring disease of the lungs in child since the age of seven months, which presents clinical and radiological signs ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : CHEMLI J,ABDENNABI H,ZORGATI M,ABDELHAK S,NABLI N,ABROUG S,SFAR MT,BEN DHIA N,AMRI F,HARBI A,

Titre : [Primary hyperoxaluria in children in central Tunisia]

Référence : Tunis Med. 2007 Jun;85(6):513-8.

Résumé :

AIM: The goal of this work is to analyze clinical and therapeutics particularities of primary hyperoxaluria in children in Tunisian centre. METHODS: We studied retrospectively 15 cases of primary hyperoxaluria enrolled during 9 years period (1994-2002). RESULTS: It is about 2 boys and 13 girls (sex - ratio = 4.5) aged 2 month to 13 years (mean age: 4 years). Six patients presented the infantile form and nine the juvenile form of HP. At the moment of diagnosis, renal function was normal in one pa ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BEN HARIZ M,KALLEL-SELLAMI M,KALLEL L,LAHMER A,HALIOUI S,BOURAOUI S,LAATER A,SLITI A,MAHJOUB A,ZOUARI B,MAKNI S,MAHERZI A,

Titre : Prevalence of celiac disease in Tunisia: mass-screening study in schoolchildren.

Référence : Eur J Gastroenterol Hepatol. 2007 Aug;19(8):687-94.

Résumé :

BACKGROUND: Celiac disease is reported to be common among North Africans, particularly Tunisians. Nevertheless, the prevalence of coeliac disease in the general population has not been previously investigated. OBJECTIVE: This study aimed to determine the prevalence of celiac disease among children in Tunisia and to describe the clinical profile of the screened patients. METHODS: A mass screening study based on drawing lots was carried out on schoolchildren in Ariana, a Tunisian district. A parti ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : KAMMOUN H,JALLOULI M,GOUIAA N,BOUDAUARA TS,MHIRI R,

Titre : Unusual location of a capillary hemangioma: inguinal location.

Référence : Aesthetic Plast Surg. 2007 Sep-Oct;31(5):593-5. Epub 2007 Jun 18.

Résumé :

A 3-month-old girl presented to the Department of Pediatric Surgery because of a strangled inguinal hernia. The exploration using an inguinal approach showed a blue-reddish, moderately firm, circumscribed subcutaneous mass. Pathologic examination of the resected tissue confirmed the diagnosis of capillary hemangioma. To the authors' knowledge, this is the first reported case of a capillary hemangioma occurring in this location. They provide a review of the current literature on capillary hemangi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : CHEMLI J,KETATA S,DALHOUMI A,AJMI H,HASSAYOUN S,FODHA I,BOUJAAFAR N,HARBI A,

Titre : [Opsoclonus-myoclonus syndrome associated with Mycoplasma pneumoniae infection]

Référence : Arch Pediatr. 2007 Aug;14(8):1003-6. Epub 2007 May 31.

Résumé :

Mycoplasma pneumoniae infection is associated with various manifestations involving the central nervous system but it has never been reported as a potential aetiology of opsoclonus-myoclonus syndrome (OMS) in children. OBSERVATION: We report on a case in a 4-year-old girl who presented neurological manifestations compatible with an OMS, after a respiratory tract disease. Aetiological investigations revealed M. pneumoniae infection as specific IgM were present in the serum (Elisa). Evolution afte ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : HAMZAOUI M,GASMI M,SAHLI S,ESSID A,HOUISSA T,

Titre : [Acute cholangitis revealing a primary pancreatic hydatid cyst in a child]

Référence : Gastroenterol Clin Biol. 2007 Apr;31(4):428-30.

Résumé :

Pancreatic hydatid cysts represent 0.1 to 1% of all hydatidoses. A 12 year-old-boy, with a previous history of abdominal pain, was admitted for acute cholangitis. Laboratory investigations showed cholestasis, cytolysis and eosinophilia. Serum amylase levels were normal. Abdominal ultrasound and CT scan revealed a 100 mm hydatid cyst, located in the head of the pancreas. The biliary and pancreatic ducts were markedly dilated. Exploratory laparotomy confirmed the diagnosis. A pancreatic fistula wa ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MATOUSSI N,BEN SLIMA S,FITOURI Z,MARRAKCHI S,BEN BECHER S,

Titre : [Uveitis of children: a report of 18 cases]

Référence : Arch Pediatr. 2007 Jul;14(7):856-60. Epub 2007 Apr 18.

Résumé :

Childhood uveitis is a rare but serious disease that may causes visual loss. Causes are various and an underlying disease is not always found. PURPOSE: To analyse clinical features and prognosis of uveitis in children. PATIENTS AND METHODS: A retrospective, descriptive study of cases observed in a general pediatric unit over a period of 15 years (1990-2005) at Tunis. RESULTS: We gathered 18 cases of uveitis (girls 55.6% ,boys 44.4%). Mean age at the diagnosis was 8+/-3 years. Diagnosis was made ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,BOUKADIDA H,SELMI H,ESSOUSSI S,HARBI A,

Titre : [Henoch Schonlein purpura in children: clinical and evolutive study of 122 cases]

Référence : Tunis Med. 2007 Jan;85(1):54-60.

Résumé :

AIM: Analyze the clinical and evolutive particularities of Henoch Schonlein purpura in children METHODS: We studied retrospectively 122 cases enrolled in the pediatrics department of Sousse during 10 years period (1992-2001). RESULTS: It is about 66 boys and 56 girls (sex - ratio= 1.18) aged 3 to 13 years (mean age: 7 years and half). The diagnosis has been established clinically on the presence of cutaneous syndrome with symmetrical declivitous region purpura in all patients with articular synd ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : MRAD SM,BOUKTHIR S,FETNI I,SFAIHI L,DABBABI A,BARSAOUI S,

Titre : [Severe corrosive oesophagitis : are high doses of methyl prednisolone efficient to prevent oesophageal caustic stricture in children?]

Référence : Tunis Med. 2007 Jan;85(1):15-9.

Résumé :

BACKGROUND: Corrosive oesophagitis stricture is the long term complication of severe corrosive oesophagitis. The aim of our study was to evaluate the effect of a high doses of steroids on incidence and quality of oesophageal stricture. PATIENTS AND METHODS: We reviewed the case histories of 28 children seen at children hospital from 31 December 1991 to 31 december 2001. These children has second and third degree oesophageal burns and they were treated by systemic Methylprednisolone (1000mg/1,73/ ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,OUEDERNI M,BARSAOUI S,

Titre : [A new case of acute transverse myelitis following hepatitis A virus infection]

Référence : Med Mal Infect. 2007 Apr;37(4):237-9. Epub 2007 Mar 1.

Résumé :

Transverse myelitis is a rare manifestation of hepatitis A virus infection. We report the case of an eleven-year-old girl who presented a progressive flabby paraplegia with sphincter incontinence, superficial hypoesthesia, without deep involvement. Medullar MRI was suggestive of myelitis. Despite the absence of jaundice and hepatic cytolysis, the serology yielded a high rate of anti-hepatitis A immunoglobulin M. Neurological disorders disappeared within 15 days, after treating with a high dose o ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MELLOULI F,EL BORGI W,KAABI H,BEN HASSEN E,SASSI R,HMIDA H,CHERIF G,MAAMAR M,ZOUARI B,BOUKEF K,BEJAOUI M,HMIDA S,

Titre : [HFE gene mutations in Tunisian major beta-Thalassemia and iron overload]

Référence : Transfus Clin Biol. 2006 Dec;13(6):353-7. Epub 2007 Feb 15.

Résumé :

OBJECTIVES: In this study we have determined the allele frequency of HFE mutations H63D and C282Y in a group of Tunisian beta-thalassemia major patients. These two mutations are implicated in hereditary hemochromatosis among Caucasians. In this study we wanted to correlate these mutations with the iron status in major beta-thalassemia patients. DESIGN AND METHODS: Fifty Tunisian major beta-thalassemia were screening for the C282Y and H63D by digestion of polymerase chain reaction products (RFLP) ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : CHEMLI J,BARBOUCHE MR,MISSAOUI N,LAKHOUA Y,DELLAGI K,ESSOUSSI AS,HARBI A,

Titre : [Mycobacterial infections in children in Central Tunisia. A study of 31 cases including 7 disseminated BCG-osis]

Référence : Tunis Med. 2006 Dec;84(12):777-81.

Résumé :

In order to analyze the current epidemiological pattern of mycobacterial infection in children in Central Tunisia, we studied retrospectively the clinical feature of 31 children with mycobacterial infection enrolled in the pediatrics department of Sousse during eight years period (1994-2001). Twenty three boys and eight girls aged two months to 13 years (mean age: 4 years and 8 months) were investigated. Among them, 24 patients suffered of tuberculosis (TBC) and 7 of disseminated BCG-osis. Pleur ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUGHAMOURA L,CHAABANE F,TILOUCHE S,CHABCHOUB I,KABACHI N,TLILI K,YACOUB M,ESSOUSSI AS,

Titre : [Canavan disease or N-acetyl aspartic aciduria: a case report]

Référence : Arch Pediatr. 2007 Feb;14(2):173-6. Epub 2006 Dec 28.

Résumé :

Canavan disease or N-acetyl aspartic aciduria, is an autosomal recessive leukodystrophy characterized by spongy degeneration of brain. The disease is an inborn error of metabolism caused by aspartoacylase deficiency resulting from accumulation of N-acetyl aspartic acid in the brain. The authors report a case in a 10-month-old boy who presented with developmental delay and megalencephaly noticeable after 4 months of age. Magnetic resonance imaging of the brain showed diffuse white matter degenera ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : BEDOUI A,BRAHAM M,MAHJOUB B,AYADI A,BEN HOMOUDA H,BOUSSOFFARA R,ALI LACHTAR M,METHLOUTHI J,ABID F,SFAR MT,

Titre : [Severe community acquired pneumonia due to Staphylococcus aureus in children. About two cases]

Référence : Tunis Med. 2006 Oct;84(10):666-9.

Résumé :

The staphylococcal pneumonia is the prerogative of the infant but rare cases were observed in the childhood. We report the observation of two children aged respectively of six years and three years and a half having presented a particular form of severe staphylococcal pneumonia apart from any context of immunodepression. The identification of the particular strains producing toxins Like the Panton and Valentine leukocidin constitutes the first stage of the comprehension of this atypical form of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Tahar Sfar

____________________________________________________________________________________


Auteurs : MATOUSSI N,AISSA K,FITOURI Z,CHEOUR M,BEN BECHER S,

Titre : [Hyperlipidaemia associated to inaugurated diabetic ketoacidosis]

Référence : Tunis Med. 2006 Oct;84(10):658-9.

Résumé :

Severe hyperlipidaemia in presenting diabetic ketoacidosis was rarely reported in child. We report the case of a three-year-old girl with presenting diabetic ketoacidosis. Family history was negative for hyperlipidaemia. Serum was creamy pink in gross appearance. The child has a hyperlipidaemia with serum triglycerides 18.5 mmol/l and serum cholesterol 13.8 mmol/l. The hyperlipidaemia disappeared with insulin therapy within seven days. We study the clinical, laboratory, pathogenic and evolution ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUJEMAA Z,AOUN S,HAMMAMI O,CHEBBI Y,ZAGHBIB A,GANDOURA N,

Titre : [Epidemiologic profile of the newborn of unmarried mother in Bizerta. About 187 cases]

Référence : Tunis Med. 2006 Oct;84(10):636-9.

Résumé :

The aim of this study is to establish the epidemiologic profile of 187 illegitimatepregnancies compared topregnancies from married mothers. PATIENTS AND METHODS: A transversal retrospective study was carried out in Bizerta from 1990 to 2003. The witness group was constitued by women whose gonna delivery at the same period with p < 0.05. RESULTS: Throughout this study, we have found that single mothers with a mean age of 24 years, are younger than married mothers and has a rural origin and primip ...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Hopital Régional de Bizerte Habib Bougatfa

____________________________________________________________________________________


Auteurs : MAZIGH M'RAD S,BOUKTHIR S,AISSA K,FETNI I,BARSAOUI S,

Titre : [Upper gastrointestinal endoscopy in neonates--experience of pediatric gastroenterology unit]

Référence : Tunis Med. 2006 Oct;84(10):607-10.

Résumé :

The aim of our study was to assess the frequency of the different lesions occurring as well as to precise indications of upper gastrointestinal endoscopy in neonates. Method :We have achieved a retrospective study about 128 neonatal gastrointestinal endoscopies. Three groups were constituted according to macroscopic findings: Group I: normal aspect (n=11); Group II: isolated esophagitis (n=19); Group III: esogastritis or gastroduodenitis or esogastroduodenitis (n=92). RESULTS: The neonates under ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : THABET F,TILOUCHE S,TABARKI B,AMRI F,GUEDICHE MN,SFAR MT,HARBI A,YACOUB M,ESSOUSSI AS,

Titre : [Pneumococcal meningitis mortality in children. Prognostic factors in a series of 73 cases]

Référence : Arch Pediatr. 2007 Apr;14(4):334-7. Epub 2006 Dec 21.

Résumé :

OBJECTIVE: Despite advances in antibiotic therapy strategies and pediatric intensive care, prognosis of Streptococcus pneumoniae meningitis remains very poor. To determine the factors associated with hospital mortality of children with pneumococcal meningitis. METHODS: We conducted a retrospective study of 73 cases of childhood pneumococcal meningitis admitted in 4 teaching hospitals in the center of Tunisia during a 8-year period (1995-2002). RESULTS: Hospital mortality was 13.7% (10 of 71 pati ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MAZIGH MRAD S,OUBICH F,BOUSSIF A,DEBBABI A,BARSAOUI S,

Titre : [Colorectal polyps in children. A study of 34 patients]

Référence : Tunis Med. 2006 Aug;84(8):496-9.

Résumé :

AIM: To assess the frequency and the clinical features of polyps of the colon and rectum in children. METHODS: A total of 34 patients (20 boys and 14 girls, mean age: 5.4 years) were enrolled in this 14-years retrospective study. Diagnosis was done for almost all patients by colonoscopy (n=8) or recto-sigmoidoscopy (n= 19). After endoscopic polypectomy, polyp's type is determined by histological examination. RESULTS: Minimal and relapsing rectal bleeding was the most frequent finding of polyps o ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : ZOUARI S,KHALDI F,

Titre : [Sensitization to pollen in the asthmatic child. A study of 86 cases]

Référence : Tunis Med. 2006 Aug;84(8):470-2.

Résumé :

This retrospective study was designed to determine the place of pollen sensibilization in asthmatic child and to assess its epidemiological and clinical characteristics. 86 from 638 asthmatic child were allergic to pollen and included in the study. The mean age was 4 years (extremes : 1-12 years). The mean age of first respiratory manifestations was 1 and half years. The male/female ratio was 1.46. Asthmatic attacks was noted in 77% of cases, chronic cough was the only allergic manifestation in ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,ABROUG M,TLILI K,HARBI A,

Titre : Rhombencephalosynapsis diagnosed in childhood: clinical and MRI findings.

Référence : Eur J Paediatr Neurol. 2007 Jan;11(1):35-8. Epub 2006 Nov 9.

Résumé :

Rhombencephalosynapsis (RES) is a rare cerebellar malformation of unknown etiology characterized by vermal agenesis or hypogenesis, fusion of hemispheres and the dentate nuclei. Clinical presentation and prognosis are extremely variable and generally depends one the associated supratentorial anomalies. We report the first Tunisian case of RES diagnosed by magnetic resonance imaging (MRI) in a 3.5-year-old boy born to consanguineous parents. The child had spastic diplegia, facial dysmorphia, skel ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : HALIOUI-LOUHAICHI S,BEN HARIZ M,FATHALLAH DAHMANI M,BARBOUCH MR,MAHMOUDI J,BEJAOUI M,FISCHER A,DELLAGI K,BEN AMMAR B,MAHERZI A,

Titre : [Deficient expression of leukocyte adhesion proteins. A new Tunisian case]

Référence : Tunis Med. 2006 Jul;84(7):464-6.

Résumé :

Leukocyte adhesion deficiency (LAD) is a rare primary immunodeficiency inherited as an autosomal recessive genetic disorder. LAD was suspected in a four days old girl. She was born from healthy first cousins. A family history of a boy who died from omphalitis and sepsis was reported. Our patient had the severe form, she had delayed umbilical cord separation and suffered recurrent infections. She had a deletion of the G at position 1497. The patient received bone marrow transplantation from her H ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : THABET F,TILOUCHE S,TABARKI B,BOUKADIDA J,YACOUB M,ESSOUSSI AS,

Titre : [Listeria monocytogenes meningitis in an immunocompetent child]

Référence : Arch Pediatr. 2006 Dec;13(12):1553-4. Epub 2006 Oct 9.

Résumé :

...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : pas d'institution définie

____________________________________________________________________________________


Auteurs : BEN JABALLAH N,MNIF K,KHALDI A,BOUZIRI A,BELHADJ S,HAMDI A,

Titre : High-frequency oscillatory ventilation in term and near-term infants with acute respiratory failure: early rescue use.

Référence : Am J Perinatol. 2006 Oct;23(7):403-11. Epub 2006 Sep 25.

Résumé :

This study describes a high-frequency oscillatory ventilation (HFOV) protocol for term and near-term infants with acute respiratory failure (ARF) and reports results of its prospective application. Neonates, with gestational age >or= 34 weeks, were managed with HFOV, if required, on conventional ventilation (CV), a fraction of inspired oxygen (F IO(2)) 0.5, and a mean airway pressure > 10 cm H (2)O to maintain adequate oxygenation or a peak inspiratory pressure > 24 cm H (2)O to maintain tidal v ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,BRAHAM N,BOUGHATTAS S,HARBI A,

Titre : [Basedow's disease and celiac disease in an adolescent with Down syndrome]

Référence : Rev Med Interne. 2006 Oct;27(10):791-3. Epub 2006 Jun 2.

Résumé :

INTRODUCTION: Down syndrome is a favourable land to the emergence of auto-immune disease. CASE RECORD: Graves' disease and celiac disease were diagnosed in a 16 years old adolescent with Down syndrome presenting chronic diarrhoea, important delayed development and signs of hyperthyroidism. DISCUSSION: Celiac disease and thyroid dysfunction would be screening in patient with Down syndrome. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUGHAMOURA L,YACOUB M,ABROUG M,CHABCHOUB I,BOUGUEZZI R,CHARFEDDINE L,AMRI F,ESSOUSSI AS,

Titre : [Gillespie syndrome: 2 familial cases]

Référence : Arch Pediatr. 2006 Oct;13(10):1323-5. Epub 2006 Aug 17.

Résumé :

We report 2 familial cases of Gillespie syndrome in an 8-year-old girl and her brother 16 months old. They had both congenital aniridia, cerebellar ataxia and mental retardation. In the girl, pupillar dilation in the 2 eyes and delay in different milestones development were elicited at 2 years. She was summoned at the birth of her brother that had pronounced floppiness and the same ocular abnormalities. Ophtalmological exam confirmed partial and bilateral aniridia in both sibs. Brain MRI showed ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : BRAHEM M,HLEL K,AYADI A,BEDOUI A,HMILA F,MAHJOUB B,BOUSSOFFARA R,SFAR MT,

Titre : [Cerebral hydatid cysts in children: 4 cases]

Référence : Med Mal Infect. 2006 Aug;36(8):434-7. Epub 2006 Aug 4.

Résumé :

The cerebral localization of the hydatid disease is rare, under 2%, and it primarily affects children. We report 4 cases of children presenting with a cerebral hydatid cyst (2 boys and 2 girls, mean age 9 years). Clinical symptoms were very progressive, the disease was frequently diagnosed several months (1-12 months) after onset of symptoms most often headaches and vomiting. One patient presented with a right tonic-clonic seizure 3 days before hospitalization. The diagnostic was confirmed in al ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Tahar Sfar

____________________________________________________________________________________


Auteurs : CHEMLI J,ABROUG M,FATHALLAH A,ABROUG S,BEN SAID M,HARBI A,

Titre : [Contribution of leukoconcentration in the diagnosis of Kala-azar in Tunisia]

Référence : Med Mal Infect. 2006 Jul;36(7):390-2. Epub 2006 Jul 26.

Résumé :

OBJECTIVE: The authors had for aim to determine the role of leukoconcentration in the diagnosis of visceral leishmaniosis in immunocompetent children. MATERIALS AND METHODS: A study was made on leukoconcentration in blood samples of 84 immunocompetent children presenting with visceral leishmaniosis, hospitalised in the paediatric units of Sousse and Kairouan (Tunisian center) between April 1996 and March 2005. RESULTS: The study group included 34 girls and 50 boys (sex-ratio = 1.47) aged six mon ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BEN JABALLAH N,BOUZIRI A,KCHAOU W,HAMDI A,MNIF K,BELHADJ S,KHALDI A,KAZDAGHLI K,

Titre : [Epidemiology of nosocomial bacterial infections in a neonatal and pediatric Tunisian intensive care unit]

Référence : Med Mal Infect. 2006 Jul;36(7):379-85. Epub 2006 Jul 11.

Résumé :

OBJECTIVE: The authors had for aim to describe the epidemiology of nosocomial bacterial infections in the neonatal and pediatric intensive care unit of the Tunis children's hospital. DESIGN: A prospective surveillance study was made from January 2004 to December 2004. All patients remaining in the intensive care unit for more than 48 h were included. CDC criteria were applied for the diagnosis of nosocomial infections. RESULTS: 340 patients including 249 (73%) neonates were included. 22 patients ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHEMIRI M,RIDANE H,BOU YO,MATOUSSI N,KHALDI F,

Titre : [11 beta hydroxylase deficiency: a clinical study of seven cases]

Référence : Tunis Med. 2006 Feb;84(2):106-13.

Résumé :

11 beta-hydroxylase deficiency is a rare recessive autosomal disorder. The aim of this report was to describe among a retrospective study of seven cases, different clinical pictures, problems in diagnosis and management. Results: the frequency of 11 beta-hydroxylase deficiency was 17.5% of congenital adrenal hypererplasia etiology in our study. Consanguinity was found in all cases. The sex ratio was 5 boys/2 girls. Median age on diagnosis was 4.3 years. Five cases were revealed with precocious p ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MAZIGH MS,ALOUI N,FETNI I,BOUKTHIR S,AISSA K,SELLAMI N,BELLAGHA I,BOUSNINA S,BARSAOUI S,

Titre : [Congenital hepatic fibrosis in children. Report of 9 cases and review of the literature]

Référence : Tunis Med. 2006 Mar;84(3):182-8.

Résumé :

Congenital hepatic fibrosis is a recessive autosomic disease with two major risks: gastrointestinal haemorrhage caused by portal hypertension and cholangitis related to bacterial infection of dilated intrahepatic bile ducts.. The aim of our study is to define epidemiological features, the presenting symptoms, the diagnosis, the evolution and the management of this disease. Between January 1990 and December 2000, we reported the cases of nine children with this disease at children hospital of Tun ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN JABALLAH N,KHALDI A,MNIF K,BOUZIRI A,BELHADJ S,HAMDI A,KCHAOU W,

Titre : High-frequency oscillatory ventilation in pediatric patients with acute respiratory failure.

Référence : Pediatr Crit Care Med. 2006 Jul;7(4):362-7.

Résumé :

OBJECTIVE: To evaluate the effectiveness of high-frequency oscillatory ventilation (HFOV) in pediatric patients with acute respiratory failure, failing conventional ventilation. DESIGN: A prospective, clinical study. SETTING: Tertiary care pediatric intensive care unit. PATIENTS: Twenty pediatric patients (ages 12 days to 5 yrs) with acute respiratory failure (pneumonia, 14; sepsis with acute respiratory distress syndrome, 3; pulmonary edema as a complication of upper airway obstruction, 2; sali ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : THABET F,SGHIRI R,TABARKI B,GHEDIRA I,YACOUB M,ESSOUSSI AS,

Titre : ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil.

Référence : Eur J Pediatr. 2006 Jul;165(7):435-6. Epub 2006 Apr 19.

Résumé :

Benzylthiouracil has been recently observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. We report an 8-year-old girl treated with benzylthiouracil for Graves's disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage. She responded to corticosteroids and discontinuation of benzylthiouracil. This represents the first pediatric case of benzylthiouracil-induced diffuse alveolar hemorrhage. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : HACHICHA M,KAMMOUN T,CHABCHOUB I,BAHLOUL S,TURKI H,DRIRA M,ZAHAF A,TRIKI A,

Titre : [Cowden's disease: a new paediatric observation]

Référence : Arch Pediatr. 2006 May;13(5):459-62. Epub 2006 Mar 29.

Résumé :

We report on a paediatric observation of Cowden's disease in a 6-year-old child. Familial steroid-resistant nephrotic syndrome was associated to papulous and papillomatous lesions of gingiva and oral mucosa, multiple hamartoma of the back and of upper limbs, facial dysmorphism and follicular thyroid cancer. Thyroid cancer evolved favorably after surgical treatment, radioactive iodine and L-thyroxin supplementation. Nephrotic syndrome evolved to chronic renal insufficiency after 11 years. The ear ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : ZOHRA F,NADIA M,NADIA A,KHEDIJA B,MOUNA C,AZZA H,SAIDA BB,

Titre : [Chronic septic granulomatosis in children revealed by invasive pulmonary aspergillosis]

Référence : Tunis Med. 2005 Nov;83(11):717-9.

Résumé :

Chronic granulomatosis disease (GCD) is a hereditary abnormality of phagocytic cells, frequently revealed by invasive pulmonary Aspergillosis. The authors report the case of 8 year old girl investigates for hypotrophia, reccurent lung disease and hemoptysia. She was treated for pulmonary tuberculosis because of biological inflammatory syndrome, right alveolar opacity and positive tuberculin skin test. The course was marked by the developement of a thoracic wall mass. Anti- aspergillus serology w ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : FITOURI Z,FAYECH C,FERCHICHI M,BEN BECHER S,

Titre : [Arabian variant of Kenny syndrome: a familial case in Tunisia]

Référence : Ann Endocrinol (Paris). 2005 Sep;66(4):361-4.

Résumé :

Kenny syndrome is rare. Clinical feature include severe dwarfism, growth retardation macrocephaly, episodic hypocalcemia, internal cortical thickening and medullary stenosis of tubular bones. Genetic and phenotypic polymorphisms are characteristic. We report the observation of a Tunisian girl with the arabic variant of Kenny syndrome. She had chronic hypoparathyroidism, classic dwarfism, short stature with hormone deficiency, mental retardation and low helper/suppressor ratio. Our patient had tw ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : EL ATI J,GAIGI S,BEJI C,HADDAD S,CHERIF S,FARHAT A,FATTOUM S,BEN ABDELADHIM A,

Titre : [Prevalence and causal factors of anemia in children in Tunisia]

Référence : Tunis Med. 2005 Sep;83(9):511-8.

Résumé :

Anemia continue to be prevalent among children under five years despite the improvement of socioeconomic and sanitary indicators. The purpose of the present cross-sectorial study is to assess the etiologic factors responsible for anemia. Knowledge of the relative importance of the different causes should form a basis for intervention strategies to prevent and control anemia. The survey covered 955 children under the age of five years, native of two regions with the highest prevalent of anemia, t ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Institut National de Nutrition et de Technologie Alimentaire

____________________________________________________________________________________


Auteurs : MRAD SM,BOUKTHIR S,FDHILA F,FENDRI C,BARSAOUI S,

Titre : [Children Helicobacter pylori infection: antibiogram results]

Référence : Tunis Med. 2005 Oct;83(10):599-602.

Résumé :

Helicobacter pylori infection is frequent in children. The eradication rate is variable, it is influenced by resistance of the bacteria to the antibiotics used. The aim of this study was to determine the resistance rate of the most commonly used antibiotics among helicobacter pylori (Hp) strains isolated in infected children. PATIENTS AND METHODS: 60 children (26 males, 34 females), with mean age of 8 years 8 months (3 years and 2 month (2.5-13.5 years) underwent an oesogastroscopy. Forty six of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HALIOUI-LOUHAICHI S,BEN HARIZ M,HAMZAOUI A,MESTIRI T,JERBI E,LOUZIR B,BEN KHELIFA S,BEN JABALLAH N,DE BLIC J,BEN AMMAR MS,BOUBAKKER S,BEN AMMAR B,MAHERZI A,

Titre : [Pulmonary alveolar proteinosis in two siblings. A case report]

Référence : Tunis Med. 2005 Aug;83(8):488-91.

Résumé :

Pulmonary alveolar proteinosis (PAP) is a rare disorder in children. This report describes two siblings in whom PAP developed during infancy (three years for the boy and four years two months for the girl). The girl was admitted for chronic respiratory distress. Chest x-ray showed a reticulonodular pattern. Her brother was asymptomatic. The diagnosis of PAP was confirmed by open lung biopsy for the boy and broncho-alveolar lavage for the girl. Therapeutic broncho-alveolar lavages were performed ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : CHEMLI J,KCHAOU H,AMRI F,BELKADHI A,ESSOUSSI AS,GUEDDICHE N,HARBI A,

Titre : [Clinical features and course of Kawasaki disease in central Tunisia: a study about 14 cases collected over a period of three years (2000-2002)]

Référence : Tunis Med. 2005 Aug;83(8):477-83.

Résumé :

OBJECTIVE: To analyze the clinical features and course of Kawasaki disease in central Tunisia. We studied retrospectively 14 cases of children with Kawasaki disease collected in tunisian center during three years (2000-2002). The study is about 11 boys and 3 girls (sex - ratio: 3.6/1) aged from 6 months to 8 years (mean age : 4 years). Twelve patients had at least 5 diagnostic criteria of the illness, the two others had an incomplete form. We noted cardiac complications in seven patients treated ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

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Auteurs : SONIA HL,MOHAMED F,MOHAMED B,RAFIKA A,DEHMANI F,KOSSAY D,AZZA H,

Titre : [Osteopetrosis with carbonic anhydrase II deficiency: report of 24 cases]

Référence : Tunis Med. 2005 Jul;83(7):409-13.

Résumé :

Twenty four patients suffering from osteopetrosis caused by carbonic anhydrase II deficiency are colliged. This pathology seems to be frequent in Tunisia. Mental retardation is present in 52%, 85% of patients have short stature and 25% have optic atrophy. All affected subjects show craniofacial disproportion and dental anomalies. Twenty patients have at least one bone fracture. Metabolic acidosis is constant: it is profound during the first life decade. A severe selective reduction of carbonic a ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : CHOUCHANE S,FEHRI H,CHOUCHANE C,MERCHAOUI Z,SEKET B,HADDAD S,BEN MERIEM C,MONASTIRI K,GUEDICHE MN,

Titre : [Hypernatremic dehydration in children: retrospective study of 105 cases]

Référence : Arch Pediatr. 2005 Dec;12(12):1697-702. Epub 2005 Oct 10.

Résumé :

The hypernatremic dehydration defined by a serum sodium concentration> or = to 150 mmol/l, is a particular form of acute dehydration and constitutes a medical emergency requiring a prompt and adequate diagnosis and management. PURPOSE: To precise the epidemiological profile, course, causes and therapeutic particularities of hypernatremic dehydration in children. POPULATION AND METHODS: Retrospective review of 105 children admitted in the general Paediatrics department of the Fattouma Bourguiba u ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : JALEL C,FETHI D,RIDHA BH,ABDELAZIZ H,

Titre : [Indications and outcomes of surgical treatment of gastro-duodenal ulcer in child and adolescent. About 45 cases]

Référence : Tunis Med. 2005 Jun;83(6):331-4.

Résumé :

The goal of this study was to determine the indications and assess the results of surgery in the treatment of gastro-duodenal ulcers in children and adolescents. This is a retrospective study of 45 patients operated for duodenal ulcer in Sahloul Teaching Hospital (Susa, Tunisia) over period of 14 years (1988 - 2001). The study is about 41 boys and 4 girls aged between 8 and 18 years (mean age: 15 1/2 years). Surgery was undertaker in cases of bleeding ulcer (9 cases), perforation (26 cases), ste ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : BOUSSETTA K,PONVERT C,KARILA C,BOURGEOIS ML,BLIC J,SCHEINMANN P,

Titre : Hypersensitivity reactions to paracetamol in children: a study of 25 cases.

Référence : Allergy. 2005 Sep;60(9):1174-7.

Résumé :

BACKGROUND: Allergic-like reactions to paracetamol (acetaminophen) are rare. Paracetamol allergic and nonallergic hypersensitivity (HS) has been diagnosed in a few patients with skin and/or respiratory symptoms, immediate and accelerated urticaria, and angioedema especially. Most patients with HS to paracetamol were also hypersensitive to anti-inflammatory drugs (i.e. acetylsalicylic acid, ASA), suggesting that their reactions resulted from a nonallergic HS. However, anaphylactic reactions, and ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHALDI F,FAKHFAKH R,MATTOUSSI N,BEN ALI B,ZOUARI S,KHEMIRI M,

Titre : Prevalence and severity of asthma, allergic rhinoconjunctivitis and atopic eczema in 'Grand Tunis' schoolchildren: ISAAC.

Référence : Tunis Med. 2005 May;83(5):269-73.

Résumé :

The aim of this study was to assess the prevalence and severity of asthma, allergic rhinoconjunctivitis and atopic eczema in 13-14 year old children living in 'Grand Tunis'. Using the international study of asthma and allergies in childhood (ISAAC) questionnaire, 3350 schoolchildren aged 13-14 years, from the Grand Tunis (Ariana, Ben Arous, Manouba, Tunis) were studied. Our results showed that in the past year 13.2% of children had wheezed, 1.4% had more than 12 attacks and 4.3% had experienced ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HACHICHA M,KAMMOUN T,MAHFOUDH A,ALOULOU H,SFAIHI L,HAMMAMI Y,ZAGHDEN N,HACHICHA J,TRIKI A,

Titre : [The cortico-resistent idiopathic nephrotic syndrome of child. Study of 14 observations]

Référence : Tunis Med. 2005 Apr;83(4):187-93.

Résumé :

Cortico-resistent nephrosis represent 10% of idiopathic nephrosis in nephrosis in children and progresses in almost half of the cases to end-stage renal failure. 14 cases of cortico-resistant idiopathic nephrotic syndrome, collected over a period of 13 years (1990 - 2002), are reported. This study involved 10 boys and 4 girls, aged 8 years on average. A history of allergy was present in two cases. Two other children had a family history of cortico-resistant nephrosis (CRN). Consanguinity was fou ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : HALIOUI-LOUHAICHI S,AZZABI O,NEFZI L,BEN HARIZ M,BEN MRAD N,BEN AMMAR B,MAHERZI A,

Titre : [Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome]

Référence : Arch Pediatr. 2005 Jul;12(7):1120-3.

Résumé :

Cushing's syndrome reveals McCune-Albright syndrome in a minority of patients. Bilateral adrenalectomy is performed on the majority of cases. CASE REPORT: We present a case of McCune-Albright syndrome revealed by a Cushing's syndrome treated by metyrapone. Results were good, after a 4-year follow up. CONCLUSION: Treatment with metyrapone could be recommended, for some patients, in McCune-Albright syndrome with Cushing's syndrome before chirurgical treatment. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : HALIOUI-LOUHAICHI S,BEN JMAA W,BRIKI S,BEN FARHAT L,BAHRI F,BEN MRAD N,BEN HARIZ M,HENDAOUI L,MAHERZI A,

Titre : [Acute leukoencephalitis in infant treated by high-dose corticosteroid. A case report]

Référence : Tunis Med. 2005 Mar;83(3):172-5.

Résumé :

The authors report a case of acute post infectious leukoencephalitis observed in a tow-years and a half children admitted to our hospital for fiver with suddent condition deterioration, obnibulation, coma and paralysis of the 6th and 7th cranial nerve. Cerebrospinal fluid study showed lymphocytosis with negative culture. Head magnetic resonance imaging demonstrated diffuse high signals over the white matter on T2 weighted images so the diagnosis was confirmed. High dose corticosteroid therapy wa ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : BOUSSETTA K,SIALA N,BRINI I,ALOUI N,SAMMOUD A,HAMMOU A,CHAOUACHI B,BOUSNINA S,

Titre : [The hydatid cyst of the lung in children: 54 cases]

Référence : Tunis Med. 2005 Jan;83(1):24-7.

Résumé :

The purpose of this retrospective study is to clarify the clinical, radiological and evolutionary aspects of the hydatid cyst of the lung. Over a period of 9 years (January, 1983 - December, 2001), we brought together in the pediatric service B of Children's hospital of Tunis, 54 cases of hydatid cyst of the lung. The average age is of 7 years 3 months (extremes 2 and 14 years), and the sex- ratio of 1,16. 61% of the children are of rural origin. Bronchpulmonary infection is the most frequent ci ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TEJ DELLAGI R,TAGORTI R,MASSOUDI B,BEN SALAH F,BEN BADER M,DOGGUI N,BQUSSETTA K,CHAMEKH S,ZOUARI F,AMARA F,

Titre : [Children bronchiolitis: multicentric study in Tunis]

Référence : Tunis Med. 2004 Nov;82(11):1012-8.

Résumé :

This study is made in the general framework of the basic health cares program set up by Tunis regional service to fight child serious respiratory infections. It has an objective to measure bronchiolitis winter frequency for patients aged from 1 to 36 months, serious cases frequency, changing profile, the therapeutic behavior and environmental risk factors. This is a multicentric transversal study in grappa, it has taken place in Tunis between January and march 1999 with a sample size of 1340 pat ...

Specialité : Pédiatrie

Zone : Zones non Universitaires

Institution : Direction regionale des Soins de Sante de Base de Tunis

____________________________________________________________________________________


Auteurs : MAZIGH MRAD S,BOUKTHIR S,SFAIHI L,FETNI I,DABBABI A,ZOUARI B,BARSAOUI S,

Titre : [Therapeutic management and clinical course of severe caustic oesophageal burns in children treated with methyl-prednisolone. Experience at a digestive endoscopic unit]

Référence : Tunis Med. 2004 Oct;82(10):951-7.

Résumé :

We reviewed the case histories of 28 children seen at children hospital from 31 December 1991 to 31 December 2001. These children has second and third degree oesophageal burns and they were treated by systemic Methylprednisolone (1000mg/1, 73/m2 SC). We divided the 26 children in four groups according to the time we began the steroids (before or beyond the 24th hours of the accident and according the number of steroids's bolus (less or more than 21 bolus). We analysed the number and the treatmen ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MAZIGH S,FENDRI C,KALACH N,BARSAOUI S,

Titre : [Evaluation of a non-invasive test for detection of Helicobacter pylori antigenin stool from children]

Référence : Arch Pediatr. 2005 Jan;12(1):85-7.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MRAD SM,BECHER SB,KHALDI F,BARSAOUI S,

Titre : Abdominal tuberculosis in children. Report of 10 cases.

Référence : Acta Gastroenterol Belg. 2004 Jul-Sep;67(3):245-9.

Résumé :

BACKGROUND: Abdominal tuberculosis is a rare location of this infection with a lot of diagnostic difficulties. The aim of this study was to review our experience of pediatric abdominal tuberculosis with that of the literature data. PATIENTS AND METHODS: A retrospective study was conducted over a 7-year period; 10 cases of abdominal tuberculosis in children were reviewed (6 girls and 4 boys, mean age: 11 years, extremes 4-14). Eight patients enrolled in this study satisfied the following criteria ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHOUCHANE S,CHOUCHANE CH,BEN MERIEM CH,SEKET B,HAMMAMI S,NOURI S,MONASTIRI K,GUEDICHE MN,

Titre : [Prolonged fever in children. Retrospective study of 67 cases.]

Référence : Arch Pediatr. 2004 Nov;11(11):1319-25.

Résumé :

BACKGROUND: The first problem to face in prolonged fever is its etiologic diagnosis. Its incidence varies between 0,5 to 3% of all paediatric hospital-stay. Precise diagnosis need an extensive questionnary, complete physical examination and an algorithm of complementary exams. PURPOSE: To precise the epidemiologic profile and causes of prolonged fever in a children. POPULATION AND METHODS: Retrospective review of 67 children between two and 15 years old admitted in the general paediatrics depart ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : CHAABOUNI M,KRICHEN A,BEN HALIMA N,ALOULOU H,MAHFOUDH A,HACHICHA M,MESSOUD T,FATTOUM S,TRIKI A,KARRAY A,

Titre : [Cystic fibrosis of the child]

Référence : Tunis Med. 2004 Jun;82(6):516-25.

Résumé :

Cystic fibrosis was regarded a long time as exceptional in the Nord Africaine population and in particular in Tunisia what was at the origin of the ignorance of its various diagnostic and therapeutic aspects in our country. Nevertheless, with the development of the means of the diagnosis, several cases of cystic fibrosis were diagnosed these last years what will pose true problems of assumption of responsibility of these children like illustrates it well our experiment in the pediatric departmen ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN JABALLAH N,MNIF K,BOUZIRI A,KAZDAGHLI K,BELHADJ S,ZOUARI B,

Titre : High-frequency oscillatory ventilation in paediatric patients with acute respiratory distress syndrome--early rescue use.

Référence : Eur J Pediatr. 2005 Jan;164(1):17-21. Epub 2004 Oct 7.

Résumé :

In order to determine the response to high-frequency oscillatory ventilation (HFOV), used as an 'early rescue' therapy, in a cohort of paediatric patients with acute respiratory distress syndrome (ARDS), a prospective clinical study was performed in a tertiary care paediatric intensive care unit. Ten consecutive patients, aged 12 days to 5 years with ARDS and hypoxaemic respiratory failure on conventional ventilation (CV), using a lung protective strategy, were managed with HFOV early in the cou ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : CHEMLI J,ZOUARI N,BELKADHI A,ABROUG S,HARBI A,

Titre : [Hepatitis A infection and Henoch-Schonlein purpura: a rare association]

Référence : Arch Pediatr. 2004 Oct;11(10):1202-4.

Résumé :

OBSERVATION: A 10-year-old boy presented cholestatic hepatitis A virus infection confirmed by IGM anti-HAV antibody. Three days after admission, he presented a palpable purpuric rash on the declivous regions, arthralgia and abdominal pain. He met all criteria set by the American College of Rheumatology (ACR) for Henoch Schonlein purpura. The evolution was gradually favorable with no renal involvement (recoil of 3 years and half). CONCLUSION: Henoch Schonlein purpura is an exceptional extra-hepat ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : CHEMLI J,BOUGUILA J,HARBI A,ESSOUSSI AS,HIMIDA RB,BOUZOUITA H,

Titre : [Accidental caustic ingestion in Tunisian child. Study of 330 cases]

Référence : Tunis Med. 2004 May;82(5):411-9.

Résumé :

We studied retrospectively 330 cases of caustic product ingestion at the child collected in the pediatric department of Sousse (CHU Sahloul and CHU Farhat Hached) during eight years (1993-2000). It is about 194 boys and 136 girls (sex-ratio to 1.42/1) aged of 4 months at 14 years (middle age at 3 years and 5 months). Concerned products are dominated by the water of bleach (55.7%) dilute essentially (49%), caustic soda (27.9%), diluent of painting (8.5%), potash (2.7%) and the acidic products (2. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : GHEDIRA BESBES L,MESSAOUDI A,BEN MERIEM C,GUEDICHE MN,

Titre : [Profile of antimicrobial resistance of agents causing urinary tract infections in children]

Référence : Tunis Med. 2004 Mar;82(3):299-305.

Résumé :

OBJECTIVE: The management of urinary tract infection in children faces the problem of the emergence of resistant strains to antibiotics. The aim of this study is to precise the frequency of the different germs and their susceptibility to antibiotics. METHODS: We report a retrospective study concerning 200 cases of urinary tract infection hospitalised in the paediatric department of Monastir between January 1995 and December 2000. There were 58 boys and 142 girls aged between two months and 14 ye ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : CHEMLI J,ABROUG S,HARBI A,

Titre : [Henoch-Schonlein purpura and renal tuberculosis]

Référence : Presse Med. 2004 Apr 10;33(7):456-7.

Résumé :

INTRODUCTION: Henoch-Schonlein purpura (HSP) is a small vessel leucocytoclastic vasculitis with IGA deposit. Its little known underlying pathogenic mechanism probably involves an auto-immune reaction triggered-off by various antigens and notably bacterial or viral infectious agents. OBSERVATION: An HSP associated with renal tuberculosis was observed in a 12 year-old girl. Renal tuberculosis, suspected because of lumbago with aseptic leukocyturia, was confirmed by the presence of Mycobacterium tu ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : THABET F,BELLARA I,TABARKI B,KCHAOU H,SELMI H,YACOUB M,ESSOUSSI AS,

Titre : [Ischemic colitis and hemophagocytosis complicating Kawasaki disease]

Référence : Arch Pediatr. 2004 Mar;11(3):226-8.

Résumé :

Gastrointestinal manifestations of Kawasaki disease are usually limited to stomatitis, paralytic ileus, and hydrops of the gallbladder. We report a case of Kawasaki disease complicated with hemophagocytosis and ischemic colitis. CASE REPORT: A 5-year-old girl with Kawasaki disease presented with hemophagocytosis that responded to gamma-globulin therapy. On day 4 she had abdominal pain and diarrhea. CT scan showed features suggesting ischemic colitis. Symptoms resolved on total parenteral nutriti ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : CHEMLI J,YACOUBI T,GUEDIRA I,JEDDI M,KORBI S,HARBI A,

Titre : [Mixed connective tissue disease revealed by chronic lymphocytic meningitis in an infant]

Référence : Arch Pediatr. 2004 Feb;11(2):126-9.

Résumé :

Mixed connective tissue disease (MTCD) is a systemic inflammatory disorder individualised by Sharp et al. in 1972. This entity is rare in children. CASE REPORT: We report an exceptional case of MTCD revealed by lymphocytic meningitis in a two-month-and-a-half-old infant. The disease was diagnosed at the age of nine months when clinical symptomatology was completed by common signs of the illness (Raynaud's phenomenon, swollen hands), systemic lupus erythematosus-like symptoms (lymphadenopathy, sq ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : CHAABOUNI M,AOULOU H,TEBIB N,HACHICHA M,BEN BECHER S,MONASTIRI K,YACOUB M,SFAR T,ELLOUMI M,CHAKROUN N,MILED M,BEN DRIDI MF,

Titre : [Gaucher's disease in Tunisia (multicenter study)]

Référence : Rev Med Interne. 2004 Feb;25(2):104-10.

Résumé :

Gaucher's disease is one of the rare lysosomial disease that could receive substitutive enzymatic treatment which may improve considerably the prognosis of certain forms. The purpose of this work is to study the epidemiology of the disease in Tunisia, to highlight the diagnostic and therapeutic difficulties and also to precise our subsequent needs for substitutive medication. PATIENTS AND METHODS: We have conducted a retrospective survey of the hospital wards that were susceptible to take care o ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BOUKTHIR S,FETNI I,MRAD SM,MONGALGI MA,DEBBABI A,BARSAOUI S,

Titre : [High doses of steroids in the management of caustic esophageal burns in children]

Référence : Arch Pediatr. 2004 Jan;11(1):13-7.

Résumé :

Esophageal burns are frequent in some countries. Esophageal stricture is a severe complication after caustic ingestion. Its frequency is estimated to 5% and reaches 47% in severe esophagitis. AIM OF THE STUDY: To study the influence of management of severe esophageal burns with high doses of steroids in the occurrence of esophageal stricture through the experience of an endoscopic unit. PATIENTS AND METHODS: Twenty-six children with a mean age of 3.5 years (15 months-8 years) with a second b- (N ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUKTHIR S,MEJRI A,M'RAD S,BARSAOUI S,

Titre : Visceral leshmaniasis diagnosed on duodenal biopsy in a child.

Référence : Acta Gastroenterol Belg. 2003 Jul-Sep;66(3):258-9.

Résumé :

Visceral leishmaniasis is usually easy to recognize when clinical presentation is complete: splenomegaly, fever and palor associated to pancytopenia, hypoalbuminaemia and hypergamma globulinemia. Bone marrow smears, culture and serology confirm the diagnosis. We report the case of an infant in whom clinical and biological findings are suggestive of leishmaniasis and the diagnosis confirmed only by duodenal biopsy. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HAMZAOUI M,ESSID A,SAHLI S,BEN SALAH M,BOUSSEN H,BEN ATTIA M,HOUISSA T,

Titre : [Nasal angiocentric T cell-natural killer cell lymphoma with pancreatic localisation in a child]

Référence : Arch Pediatr. 2003 Nov;10(11):979-82.

Résumé :

The nasal angiocentric T-cell-natural killer cell lymphoma is an aggressive tumor, exceptional in Tunisia, which is observed especially in Asia, Mexico and South America. We report the case of an 11-year-old boy, presenting with an exuberant and ulcerative tumor of the right nasal pit. Radiological investigation evidenced a right ethmoido-frontal tumor. Evolution was characterized by the installation of abdominal pain and fever, the evidenciation of a mass within the head of the pancreas that co ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : ABDELMOULA MS,M'HAMDI Z,AMRI F,TEBIB N,BEN TURKIA H,BEN DRIDI MF,

Titre : [Visceral leishmaniasis in children: prognostic factors]

Référence : Tunis Med. 2003 Aug;81(8):535-9.

Résumé :

The morbidity and death rate of visceral leishmaniasis (VL) is important. The aim of our study is to find prognosis factors of VL. Two hundred and thirty two children with VL were retrospectively studied. These children were followed in Rabta and Kairouan hospitals between 1985 and 1998. We identify 7 prognosis factors, at the hospital admission, visit delayed more than 56 days, fever during more than 21 days, normal or low temperature, haemorrhagic syndrome hemoglobin rate < 5.5 g/dl, sedimenta ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire La Rabta

____________________________________________________________________________________


Auteurs : MEKKI M,LANDOLSI A,BELGHITH M,KRICHENE I,CHELLY S,ZAKHAMA A,JOUINI R,GOLLI M,GAHBICHE M,NOURI A,

Titre : [Malignant renal tumors before one year of age. Experience of a North African pediatric surgery service]

Référence : Ann Urol (Paris). 2003 Oct;37(5):239-43.

Résumé :

The malignant tumours of the kidney are not very frequent during the first year of life and pose diagnostic and therapeutic problems. The aim of this work is to make an analysis of the epidemiologic, clinical and anatomo-pathological characteristics of these tumours during the first year of life and a development on the therapeutic methods and their results. MATERIAL [corrected] AND METHODS: This is a retrospective study of 8 observations of malignant tumours of the kidney whose first symptomato ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : CHEMLI J,KRID S,TFEFHA A,ABROUG S,HARBI A,

Titre : [Systemic infantile mastocytosis: about a case with respiratory and digestive involvement]

Référence : Arch Pediatr. 2003 Oct;10(10):898-902.

Résumé :

Systemic mastocytosis is rare in children and is characterized by an abnormal proliferation and infiltration of mast cells in different tissues. CASE REPORT: We report a case of systemic mastocytosis presenting cutaneous symptoms during the neonatal period. Later evolution was characterized by systemic manifestations consisting of recurrent respiratory infections with wheezing and a digestive involvement that included abdominal pain, hepatosplenomegaly and a nodular, hemorrhagic infiltrate in a ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : HAMZAOUI M,ESSID A,GASMI M,BEN ATTIA M,HOUISSA T,

Titre : [Congenital mesoblastic nephroma with multiple cysts]

Référence : Prog Urol. 2003 Jun;13(3):466-9.

Résumé :

Mesoblastic nephroma is a rare, benign congenital disease with a clinical presentation similar to that of Wilms tumour. It was described for the first time by BOLANDE in 1967. The authors report the case of a 6-month-old infant admitted for investigation of an abdominal mass. The radiological assessment (ultrasonography. CT) concluded on a right intrarenal retroperitoneal tumour occupying almost all of the abdominal cavity, predominantly cystic suggesting a diagnosis of non-metastatic Wilms tumo ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : YACOUB M,MISSAOUI N,TABARLI B,GHORBEL M,TLILI K,SELMI H,ESSOUSSI A,

Titre : [Aicardi syndrome with favorable outcome]

Référence : Arch Pediatr. 2003 Jun;10(6):530-2.

Résumé :

BACKGROUND: Aicardi syndrome is usually associated with a very poor outcome. CASE REPORT: We report a particular case of Aicardi syndrome characterised by a partial agenesis of the corpus callosum associated with an arachnoidal interhemispheric cystic formation, and by a complete control of epilepsy and a favorable outcome regarding visual and psychomotor performances. CONCLUSION: A better prognosis could be expected in Aicardi syndrome when spasms occur lately and are not preceded by partial se ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : OMRANE LB,VERHAEGEN F,CHAHED N,MTIMET S,

Titre : An investigation of entrance surface dose calculations for diagnostic radiology using Monte Carlo simulations and radiotherapy dosimetry formalisms.

Référence : Phys Med Biol. 2003 Jun 21;48(12):1809-24.

Résumé :

Our aim in this work was to investigate the methodology used in the determination of the entrance surface dose (ESD) in diagnostic radiology. In kV x-rays for low-energy photons (tube potential up to 160 kV, HVL: 1-8 mm Al), the ESD is based on the use of the ratio of mass-energy absorption coefficients and backscatter factors. A full simulation of the photon and electron transport in a kilovoltage x-ray unit, using the Monte Carlo code BEAM/EGS4, was performed to obtain an accurate beam phase s ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BEN HALIMA N,KARRAY A,KRICHEN A,FEKI H,BEN SALAH M,CHABCHOUB I,HACHICHA M,MAHFOUDH A,TRIKI A,

Titre : [Inhaled corticosteroids in idiopathic pulmonary hemosiderosis: 2 cases]

Référence : Tunis Med. 2003 Apr;81(4):283-7.

Résumé :

Idiopathic pulmonary hemosiderosis, a rare clinical entity, is characterized by bleeding into the alveoli and progressive pulmonary fibrosis. It is usually treated with systemic corticosteriod during acute bleeding episodes and with prolonged courses of oral corticosteroids and/or other immunosuppressant drugs for maintenance therapy. Because prolonged treatment with these agents is frequently associated with significant side effects, favorable response to inhaled corticosteroids would be ideal ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : MELLOULI F,ARROUJI Z,DEBRE M,BEJAOUI M,

Titre : [Successful treatment of Echovirus 27 meningoencephalitis in agammaglobulinaemia with intraventricular injection of gammaglobulin. A case report]

Référence : Arch Pediatr. 2003 Feb;10(2):130-3.

Résumé :

BACKGROUND: Meningoencephalitis due to enteroviruses is particularly serious when occurring in patients with agammaglobulinaemia. This disease is associated with a high mortality and a significant risk for neurological sequelae in such circumstances. We report here a new case treated with intraventricular immunoglobulin, whose evolution was favourable. CASE REPORT: A three-year-old boy with agammaglobulinaemia, while he was treated with gammaglobulin with an IgG residual concentration of 10 g/l, ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : MAHERZI A,BOUAZIZ ABED A,FENDRI C,OUBICH F,KOUBAA C,FAUCHERE JL,BOUSNINA S,

Titre : [Helicobacter pylori infection: prospective study for asymptomatic Tunisian children]

Référence : Arch Pediatr. 2003 Mar;10(3):204-7.

Résumé :

The aim of this study was to specify epidemiologic particularities of Helicobacter pylori infection among asymptomatic Tunisian children. POPULATION AND METHODS: A sample of 191 Tunisian healthy children studied for a two-month-period of time in protection center for mothers and children in a Tunis area. The children had benefited of an oriented questionnaire and a serological study of Helicobacter pylori. RESULTS: The prevalence of Helicobacter pylori infection was 30.4% (58 of 191). This preva ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital Universitaire Mongi Slim

____________________________________________________________________________________


Auteurs : MRAD SM,ALOUI N,BEN JEDDOU A,FETNI I,OUBICH F,BOUKTHIR S,HAMMOU A,BARSAOUI S,

Titre : [Heterotopic gray matter. Report of four pediatric cases]

Référence : Arch Pediatr. 2003 Jan;10(1):34-7.

Résumé :

Severe infant epilepsy is included within difficult etiologic diagnosis. Gray matter heterotopias are an uncommon cause. The authors report four observations of gray matter heteropias concerning three-, six-, seven- and nine-year-old girls, presenting no particular antecedents. No consanguinity was noted. The first occurrence of epilepsy ranged from the age of nine months to the age of four years. A mild mental retardation was found in three cases, and mental regression in one case. A status epi ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BOUSSOFFARA R,MECHRI A,KNANI J,SLAMA R,BEN SALEM N,TABKA Z,BEN SALEM K,SFAR H,SFAR MT,

Titre : [Involved factors in stability of children's asthma. A study of 150 children in Mahdia]

Référence : Tunis Med. 2003 Mar;81(3):190-4.

Résumé :

In order to reduce the mortality and morbidity by asthma in perpetual increasing, taking in charge of asthmatic child must be general (therapeutic and educative) with the intention to stabilize il cause of the lack of curing ait. The aim of our work was to determinate the factors in stability of asthma. Our study was retrospective, inducing 150 asthmatic children regularly observed since at least 6 months and more than 4 years old: 77 of them was judged stable and 73 unstable. Stable asthma conc ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Tahar Sfar

____________________________________________________________________________________


Auteurs : BEJAOUI M,MELLOULI F,CHOUANINE R,DELLAGI K,BARBOUCHE MR,

Titre : [The hyper-IgM syndrome: 13 observations]

Référence : Presse Med. 2003 Mar 29;32(12):544-9.

Résumé :

INTRODUCTION: The hyper-IgM syndrome (HIGM) is a rare hereditary immune deficiency, characterised by a low or nil level of IgG and IgA and a normal or increased level of IgM, predominately affecting boys. Its clinical manifestations are dominated by recurrent infection, notably of the digestive tube, the ears nose and throat and the lungs. METHODS: We conducted a retrospective study of the medical files of 13 patients with 10 boys and 3 girls from 12 different families. In all the patients, the ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Centre National de Greffe de la Moelle Osseuse

____________________________________________________________________________________


Auteurs : TABARKI B,YACOUB M,TLILI K,TRABELSI A,DOGUI M,ESSOUSSI AS,

Titre : Familial spastic paraplegia as the presenting manifestation in patients with purine nucleoside phosphorylase deficiency.

Référence : J Child Neurol. 2003 Feb;18(2):140-1.

Résumé :

We report two siblings with purine nucleoside phosphorylase deficiency revealed by isolated spastic paraplegia, whereas symptoms of immune deficiency did not become apparent until 3 years of age. As the concurrence of immunodeficiency and neurologic problems strongly suggests the diagnosis of purine nucleoside phosphorylase deficiency, special attention should be paid to counts of lymphocytes in any infant with spastic paraplegia. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : HACHICHA M,MAHFOUDH A,LOULOU F,BEN AMAR H,KOLSI S,BEN SLIMEN M,REKIK S,TRIKI A,

Titre : [Hypothyroidism in children. 82 cases]

Référence : Tunis Med. 2002 Nov;80(11):663-9.

Résumé :

The hypothyroidism is a frequent endocrinopathos. The authors report a retrospective study of 67 cases gathered at pediatric department of Sfax, during 23 years. 40 boys and 42 girls aged from 1 to 164 months, with an average of 55 months old children. The most clinical symptoms have been the dysmorphic syndrome (81.17%), Huge tongue (59.75%), the T3 is low in 30.48%, the FT4 or the T4 is low in 79% and the TSH is high in 84.14%. All the patients have benefitted a treatment based on thyroidian e ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : BEN HALIMA N,CHAABOUNI M,KARRAY A,KRICHEN A,MASMOUDI H,JLIDI R,TRIKI A,

Titre : [Cyclosporine A in the treatment of autoimmune hepatitis in the child: a case report]

Référence : Tunis Med. 2002 Sep;80(9):565-9.

Résumé :

The current immunosuppressive treatment of patients with autoimmune hepatitis consists of prednisone and azathioprine. High doses of prednisone used to obtain the remission of the disease are associated with serious adverse effects. To avoid harmful consequences of prednisone, we proposed to treat patients with oral cyclosporine to obtain the remission of the inflammatory process. CONCLUSION: This case and review of the cases in the literature show that cyclosporine can induce remission of liver ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : MAZIGH MRAD S,FETNI I,RABEH O,OUBICH F,BOUKTHIR S,BARSAOUI S,

Titre : [Contribution of clinical, biological and radiological parameters in the diagnosis of urinary infection localization]

Référence : Tunis Med. 2002 Oct;80(10):628-32.

Résumé :

Urinary infection was a problem in pediatrics. Currently the diagnosis is easy but it is hard to diagnosis the localisation of the infection. We have to go fast and precisely to treat correctly this infection and diminich the possibility of developing renal scars. Dimercaptosuccinic acid (DMSA) scintigraphy is a reference exam for detection acute renal lesions. We have realised a prospective study in 29 children presenting urinary tract infection. In whom a DMSA scintigraphy is realised between ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : HACHICHA M,KAMMOUN T,KOLSI S,MAHFOUDH A,JARDAK N,ALOULOU H,BOUAZIZ N,TRIKI A,

Titre : [Delayed growth due to growth hormone deficiency (study of 16 cases)]

Référence : Tunis Med. 2002 Jun;80(6):317-23.

Résumé :

Growth hormone deficiency is one of the scarce statural backward causes. It is difficult to make a diagnosis. The purpose of growth hormone treatment is to reach a final normal height and to avoid hypoglycemia after-effects. We give a retrospective account of 16 children (11 boys and 5 girls) who have a growth-delay due to a total growth hormone deficiency confirmed by the stimulation tests and who have also been given benefit of a biosynthetic growth hormone from 1990 to 1999. The statural back ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : HAMZAOUI M,ESSID A,LAABIDI B,BEN ATTIA M,HOUISSA T,

Titre : [Neonatal congenital mega urethra]

Référence : Prog Urol. 2002 Sep;12(4):680-3.

Résumé :

Congenital megaurethra is a rare mesenchymal anomaly of the male urethra, characterized by severe dilatation of the penile urethra. The authors review the embryogenesis and management of this abnormality in the light of a case of scaphoid megaurethra observed in a new-born infant with no associated congenital anomalies who was treated successfully. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TABARKI B,KHALIFA M,YACOUB M,TLILI K,ESSOUSSI AS,

Titre : Cerebellar symptoms heralding bilirubin encephalopathy in Crigler-Najjar syndrome.

Référence : Pediatr Neurol. 2002 Sep;27(3):234-6.

Résumé :

Children with Crigler-Najjar syndrome type I are at increased risk for neurologic deficits. Cerebellar symptoms are not prominent and appear in adolescent or adult patients with this syndrome. We report a 2-year-old female with Crigler-Najjar syndrome type I who presented severe cerebellar symptoms revealing bilirubin encephalopathy. The patient improved slowly with the duration of phototherapy. Cerebellar symptoms can be the initial manifestation of kernicterus in children with Crigler-Najjar s ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : MEKKI M,BELGHITH M,KRICHENE I,ZAKHAMA A,LANDOLSI A,CHELLY S,NOURI A,

Titre : [Fetal rhabomyomatous nephroblastoma. Report of 2 cases and review of the literature]

Référence : Ann Urol (Paris). 2002 Jul;36(4):245-9.

Résumé :

OBJECTIVE: Fetal rhabdomyomatous nephroblastoma is a particular and very rare histologic variety of nephroblastoma. The aim of this work is to study the principal clinic, therapeutic and evolutive characteristics of the fetal rhabdomyomatous nephroblastoma through two personal cases and a review of the literature. PATIENTS AND METHODS: This is a retrospective study of two observations of fetal rhabdomyomatous nephroblastoma treated in the pediatric surgery departement of Monastir (Tunisia) among ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : TABARKI B,MAHDHAOUI A,YACOUB M,SELMI H,MAHDHAOUI N,BOURAOUI H,ERNEZ S,JRIDI G,AMMAR H,ESSOUSSI AS,

Titre : [Familial hypertrophic cardiomyopathy associated with Wolff-Parkinson-White syndrome revealing type II glycogenosis]

Référence : Arch Pediatr. 2002 Jul;9(7):697-700.

Résumé :

Symptoms of the late infantile form of type II glycogen storage disease are mainly due to functional impairment of skeletal muscle. Cardiac muscle can be involved in the late stage of the disease. CASE REPORT: We report the cases of two siblings seven and 12 years old with type II glycogen storage disease. The initial symptoms were hypertrophic cardiomyopathy with Wolf-Parkinson-White syndrome. CONCLUSION: Hypertrophic cardiomyopathy may be the form of presentation of the late infantile form of ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : BOUKTHIR S,FETNI I,M'RAD S,BENNOUR F,BARSAOUI S,

Titre : [Esophagogastroduodenitis in the newborn. Report of 90 cases]

Référence : Tunis Med. 2002 Jan;80(1):18-20.

Résumé :

Oesophagogastroduodenitis (OGD) is a frequent situation in the newborn and run a benign course. Ninety cases of OGD were studied. Diagnosis was established by endoscopy. Presenting symptoms are dominated by gastrointestinal bleeding (70 percent of cases). Oesophagitis and/or gastritis were observed in all cases, associated with duodenitis in 34.5 percent of cases. Evolution was good with complete recovery of the symptoms and healing of mucosal lesions in 74.4 percent of controlled patients. Path ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : KHALDI F,BOUYAHIA O,

Titre : Epidemiology of asthma in Maghrebian countries.

Référence : Pediatr Pulmonol. 2001;Suppl 23:30-1.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MONASTIRI K,SELMI H,TABARKI B,YACOUB M,MAHJOUB T,ESSOUSSI AS,

Titre : Primary antiphospholipid syndrome presenting as complicated Henoch-Schonleinpurpura.

Référence : Arch Dis Child. 2002 Feb;86(2):132-3.

Résumé :

A child showing signs of Henoch-Schonlein purpura developed a right tibiofibularvascular thrombosis. Antiphospholipid antibody tests were positive for both lupusanticoagulant and anticardiolipin antibodies. This suggests that anantiphospholipid syndrome should be considered in cases of Henoch-Schonleinpurpura and antiphospholipid antibodies should be measured to determine whetherprophylactic antithrombotic measures are needed to prevent thromboticmanifestations. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : BOUSSETTA K,JAZIRI F,BOUSNINA D,ALOUI N,MAHERZI A,KILANI T,KAMMOUN SELLAMI N,BOUSNINA S,

Titre : [Apropos of a mediastinal teratoma invading the lung]

Référence : Arch Pediatr. 2001 Dec;8(12):1344-7.

Résumé :

Mediastinal mature teratomas are rare in children. Diagnosis is often made in the presence of a complication. We report a case of a mature mediastinal teratoma, complicated by its opening in the lung. The patient was a four-year-eight-month-old girl. She was admitted for fever, cough and dyspnea. The chest radiography showed a large mediastinal mass with calcifications. The CT scans and MRI aided in establishing the diagnosis. Biological tests (alpha-foetoproteins and beta-HCG) confirmed the ben ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : BARSAOUI S,OUBICH F,KECHRID A,ZIDI F,ARROUJI Z,BEN REJAB S,

Titre : [Clinical aspects and etiology of lower respiratory tract infections in hospitalized children]

Référence : Tunis Med. 2001 Jun-Jul;79(6-7):361-5.

Résumé :

The authors report a prospective study conducted in one of the general pediatrics unit. One hundred one children, aged 20 days to 12 years, admitted with acute lower respiratory tract infections have been studied on clinical paraclinicals and etiology grounds. All children had a chest Ray roentgenogram, a total blood cell count and C-reactive protein. The detection of a viral agent in nasopharyngeal aspirate by immunofluorescent technic were performed. 85% of patients have bronchiolitis, the che ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : TABARKI B,MAHDHAOUI A,SELMI H,YACOUB M,ESSOUSSI AS,

Titre : Kawasaki disease with predominant central nervous system involvement.

Référence : Pediatr Neurol. 2001 Sep;25(3):239-41.

Résumé :

A 4-year-old female was hospitalized with clinical and electroencephalographic evidence of acute encephalopathy. Five days later the classic signs of Kawasaki disease appeared. The neurologic outcome in this female was poor despite early treatment with immunoglobulin. Like many other vasculitidies, Kawasaki disease can have predominant neurologic symptoms as the initial presentation and during the subsequent evolution of the condition. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : CHAABOUNI M,BEN SLIMEN M,BOUDAWARA M,BEN AMAR H,MAHFOUDH A,AYADI F,BEN HALIMA N,HACHICHA M,KARAAY A,TRIKI A,

Titre : [Mucopolysaccharidoses in children. Experience of a general pediatric service. 11 cases]

Référence : Tunis Med. 2001 Apr;79(4):222-30.

Résumé :

The mucopolysaccharidosis are hereditary diseases. The neurological attack constitutes the principal factor of gravity of these affections. We conducted a retrospective study over a period of 12 years (1988-1999) in the pediatric department of Sfax University Hospital. This study allowed us to observe 11 cases of mucopolysaccharidosis confirmed by an enzymatic proportioning, with 3 cases of Hurler disease (IH), 3 cases of the disease of sanfilippo, (two II A and one III B), 3 cases of the diseas ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sfax

Institution : Hopital Universitaire Hedi Chaker

____________________________________________________________________________________


Auteurs : TABARKI B,YACOUB M,SELMI H,OUBICH F,BARSAOUI S,ESSOUSSI AS,

Titre : Infantile status epilepticus in Tunisia. Clinical, etiological and prognostic aspects.

Référence : Seizure. 2001 Jul;10(5):365-9.

Résumé :

This retrospective study includes 139 infants (74 girls and 65 boys) treated for status epilepticus at two University hospitals in Tunisia between 1990 and 1997. Their mean age was 11 months. The majority of seizures were generalized (74%) and lasted between 30 minutes and 1 hour (70%). The cause of status epilepticus was classified as acute symptomatic in 56, febrile in 57, remote symptomatic in nine, progressive neurologic in 10 and idiopathic in seven. Overall mortality was 15.8% and neurolog ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : TABARKI B,OTHMANI K,OUBICH F,YACOUB M,SELMI H,ABROUG S,ATTIA L,BARSAOUI S,HARBI A,ESSOUSSI AS,

Titre : [Guillain-Barre syndrome in children. Report of 39 cases]

Référence : Tunis Med. 2001 Mar;79(3):183-7.

Résumé :

The authors report a retrospective study of 39 cases of Guillain-Barre syndrome in children. Including 23 boys and 16 girls. The mean age was 4 years (14 months to 10 years). A history of infection preceded the polyradiculoneuritis in 75% of cases. The mean duration of extensive phase and of the maximum paralysis was 10 days. A severe respiratory involvement was observed in 9 children and cranial nerve paralysis in 8 children. An early raised cerebrospinal fluid protein concentration was found i ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : THABET F,MRAD S,ABROUG S,HATTAB N,HARBI A,

Titre : [Medullary arteriovenous malformations in children]

Référence : Arch Pediatr. 2001 May;8(5):508-11.

Résumé :

Spinal arteriovenous malformations are rare lesions in children but may produce serious functional disorders and residual handicaps. CASE REPORT: We report the case of a 10-year-old patient who had weakness in his left leg with intermittent urinary incontinence. Neurological examination showed a spastic paraparesis of both legs, more obvious in the left leg. MRI led to the diagnosis of a spinal vascular malformation, which was confirmed by angiography. The patient underwent a session of emboliza ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Sahloul

____________________________________________________________________________________


Auteurs : MEKKI M,SAID M,BELGHITH M,KRICHENE I,CHELLY S,JOUINI R,NOURI A,GANNOUNI A,

Titre : [Pneumatic dilatation of caustic esophageal stenosis in children. Report of five cases]

Référence : Arch Pediatr. 2001 May;8(5):489-92.

Résumé :

The ingestion of caustic substances is a frequent accident in the child. The treatment of caustic strictures of the esophagus, which constitute the most frightening complication, varies from conservative treatment to esophageal replacement. We report the preliminary results of a prospective work established since July 1998 and aimed at evaluating the role of pneumatic dilatation in the treatment of these injuries. STUDIED POPULATION: The series included five boys with an average age of six years ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : OULD KHALIFA I,SELMI H,TABAEKI B,OULD BEDDI M,SIDI MOHAMED AO,YACOUB M,SAHLOUL ESSOUSSI A,

Titre : [Cerebromeningeal tuberculosis: 15 pediatric cases]

Référence : Tunis Med. 2001 Jan;79(1):20-5.

Résumé :

Fifteen patients (9 girls and 6 boys) with different forms of cerebromeningeal tuberculosis (meningitis: 13 cases, tuberculoma: 2 cases) was reported. Their mean age was 6 years (4 months to 14 years). The initial diagnosis was difficult. Half patients had meningism, abnormal mental state and defects signs. The cerebrospinal fluid (CSF) leukocyte count was > 20/mm3, protein > 1 g/l (66%) and glucose < 2.2 mmol/l (80%). BK was isolated in 7 patients. Five patients (33%) died. Major neurological s ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : MEKKI M,BELGHITH M,KRICHENE I,CHELLY S,GOLLI M,ZAKHAMA A,GANNOUNI A,NOURI A,

Titre : [Esophageal duplication in children. Report of 7 cases]

Référence : Arch Pediatr. 2001 Jan;8(1):55-61.

Résumé :

Esophageal duplications represent 10 to 20% of esophageal malformations and 15 to 20% of digestive duplications. METHODS: The authors report a series of seven cases observed between 1985 and 1999. RESULTS: The sex ratio was 2.5. The diagnosis was made before the age of six months in five cases. The clinical presentation included respiratory signs in six cases and digestive signs in five cases. The diagnosis was made on the association of a mediastinal mass behind vertebral malformation in five c ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Fattouma Bourguiba

____________________________________________________________________________________


Auteurs : TABARKI B,THABET F,SELMI H,YACOUB M,MOKNI M,KORBI S,ESSOUSSI AS,

Titre : [Acute rhabdomyolysis disclosing polymyositis in children]

Référence : Arch Pediatr. 2001 Jan;8(1):51-4.

Résumé :

Traumatic and non-traumatic rhabdomyolysis have been mostly reported in adults. Polymyositis rarely leads to rhabdomyolysis. CASE REPORT: We report the case of a 13-year-old girl with rhabdomyolysis. Full recovery was observed after symptomatic treatment. Nine months later she developed polymyositis. CONCLUSION: Long-term follow-up is necessary for rhabdomyolysis, even in those cases with an isolated occurrence caused by viral infection. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Sousse

Institution : Hopital Universitaire Farhat Hached

____________________________________________________________________________________


Auteurs : KHALDI F,BOUGUERRA F,

Titre : Feeding practices, growth, and morbidity in Tunisia.

Référence : Pediatrics. 2000 Nov;106(5):1275-6.

Résumé :

...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

____________________________________________________________________________________


Auteurs : MAZIGH M'RAD S,SGHAIER K,BOUKTHIR S,BARBOUCH R,BARSAOUI S,

Titre : [Chronic septic granulomatosis in a young girl manifesting as invasive pulmonaryaspergillosis and flaccid paraplegia].

Référence : Tunis Med. 2000 Mar;78(3):210-5.

Résumé :

The invasive Pulmonary Aspergillosis (IPA) is the principal cause of death inpatients with chronic granulomatosis disease (CGD). It can happen before age ofone and can reveal the (CGD). Usually, the transmission of GSD is linked to x in65% of cases. We report, the case of a girl aged 3 years issued from consanguinemarriage referred to hospital for hemoptysia. We note that at 40 days shepresents an suppurate adenitis. She is hypotrophic at--3DS without respiratoryproblem, she have a splenomegaly. ...

Specialité : Pédiatrie

Zone : UniversitÚ de Tunis

Institution : Hopital d'Enfants

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Auteurs : AYADI A,MAHJOUB B,BEN HAMMOUDA H,BRAHAM M,SOUA H,HAMZA H,SFAR MT,NOURI A,ESSABAH M,

Titre : [Primary vesicoureteral reflux: report of 100 pediatric observations]

Référence : Ann Urol (Paris). 2000 Jun;34(3):165-70.

Résumé :

In this study, the authors have reported 100 cases of primary vesico-ureteral reflux (VUR) which occurred over a 7-year period. Patient age at presentation ranged from 1 month to 13 years, with a mean age of 3 years and 5 months. Overall, a higher rate of reflux was observed in the female population (63%) which was particularly evident after the age of 3 years, but with a male predominance during the first 12 months of life. In the majority of cases, the diagnosis of VUR was made following diagn ...

Specialité : Pédiatrie

Zone : UniversitÚ de Monastir

Institution : Hopital Universitaire Tahar Sfar

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